About: Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation

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About: Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation Goto Sponge NotDistinct Permalink

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scientific article published in Journal of Biological Chemistry

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2006 (uk) article publié dans la revue scientifique Journal of Biological Chemistry (fr) im August 2006 veröffentlichter wissenschaftlicher Artikel (de) scientific article published in Journal of Biological Chemistry (en)
publication date	wds:Q61771856-B741E701-629E-46D3-AFDA-C37D5F2A17E3
publication date	2006-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q61771856-44BA1051-C16C-47C2-8A57-8B3F288FC593
language of work or name	English
author name string	wds:Q61771856-BD4C82C2-FA55-476D-A5BD-A39951AD919C
author name string	Andrée Labelle
rdfs:label	Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation (en) Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation (nl)
skos:prefLabel	Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation (en) Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation (nl)
name	Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation (en) Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation (nl)
author	wds:Q61771856-076C263A-55C0-4E58-9906-6BB5C69AA6C9 wds:Q61771856-A099D410-D1DD-4587-A50E-5F35F71F969F wds:Q61771856-C387162D-FCEC-4D75-9FEE-C1D42F6375B6 wds:Q61771856-E21BC317-6930-4C5B-B3B5-D54CFF8B9244 wds:Q61771856-EC5E5EAC-F9D1-4A6A-8933-27793FEC25CD
author	Renato V. Iozzo Marie-Josée Hébert Jun-Ichi Abe Patrick Laplante Marc-André Raymond
title	wds:Q61771856-C4CCAE76-2991-4504-AC93-C6182937C1D4
title	Perlecan proteolysis induces an alpha2beta1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation (en)
page(s)	wds:Q61771856-3D9C1807-B26B-433C-AF12-D6F02A718A76
page(s)	30383-30392
instance of	wds:Q61771856-085A80DB-C74D-4BD5-AF35-09A4A5F7977B
instance of	scholarly article
main subject	wds:Q61771856-5672F6DB-BBEB-4783-8BEB-7F9F79781C78 wds:Q61771856-DE6EA175-E0BF-4D46-9541-6F9722CF2E38
main subject	proteolysis apoptotic process
PubMed ID	wds:Q61771856-498E2175-6AC4-4F60-9C21-51BEBC0D4F77
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16882656
PubMed ID	16882656
published in	wds:Q61771856-2A93BA45-7C3A-42C9-91BC-825F1D769655
published in	Journal of Biological Chemistry
issue	wds:Q61771856-F2DC872D-678B-4A2B-ABF7-BA3DDA174079
volume	wds:Q61771856-685FAE0B-64CC-4020-9F7F-513C1C4AB0BF
issue	41
volume	281
DOI	wds:Q61771856-CF050ECB-68E4-43C0-A5A6-0D5C188CE586
DOI	http://dx.doi.org/10.1074/JBC.M606412200
DOI	10.1074/JBC.M606412200
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q61771856
is cites work of	Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy Endorepellin evokes autophagy in endothelial cells Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor Proteomic profiling of endorepellin angiostatic activity on human endothelial cells Diverse cell signaling events modulated by perlecan. Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis. Mast cells produce novel shorter forms of perlecan that contain functional endorepellin: a role in angiogenesis and wound healing. A novel peptide sequence in perlecan domain IV supports cell adhesion, spreading and FAK activation Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact Proteoglycans in cancer biology, tumour microenvironment and angiogenesis Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines Novel insights into the function and dynamics of extracellular matrix in liver fibrosis Proteoglycan form and function: A comprehensive nomenclature of proteoglycans Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis The bone morphogenetic protein 1/Tolloid-like metalloproteinases Caspase-3-mediated secretion of connective tissue growth factor by apoptotic endothelial cells promotes fibrosis Caspase-3-dependent export of TCTP: a novel pathway for antiapoptotic intercellular communication Oxygen-glucose deprivation and interleukin-1α trigger the release of perlecan LG3 by cells of neurovascular unit Caspase activation regulates the extracellular export of autophagic vacuoles Targeting SRC in glioblastoma tumors and brain metastases: rationale and preclinical studies Proteolytically Derived Endogenous Angioinhibitors Originating from the Extracellular Matrix Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF. Oxygen-glucose deprivation (OGD) and interleukin-1 (IL-1) differentially modulate cathepsin B/L mediated generation of neuroprotective perlecan LG3 by neurons Impact of ischemia-reperfusion on extracellular matrix processing and structure of the basement membrane of the heart Antitumor effects of immunotoxins are enhanced by lowering HCK or treatment with SRC kinase inhibitors SRC family kinase (SFK) inhibition reduces rhabdomyosarcoma cell growth in vitro and in vivo and triggers p38 MAP kinase-mediated differentiation The apoptotic program promotes tissue remodeling and fibrosis
is cites work of	wds:Q26800258-C10F0DA4-1628-4E4A-9DC4-40B0FB6FF161 wds:Q36229334-2313D44A-301E-4D81-835E-5C38E6CD371F wds:Q36187777-F01AF48B-2331-4455-8A9B-F03592733A85 wds:Q35804438-53017309-03E6-45E4-8BD3-0AF9E7B4B2DC wds:Q40053261-BAE7E88A-A696-46AC-B6CA-F4C2495C2B4B wds:Q24312922-BAE497E2-AFF4-4CBA-9076-CFE5B7142D85 wds:Q35622533-37A5058E-EC7B-4FE7-BD76-188BC1A60463 wds:Q37494563-3FDE2EF9-1457-4ED0-97AE-5ED2BCA23162 wds:Q36787608-BCC89C9C-BE51-47A1-A814-4D1F8EC79D17 wds:Q36512309-C0B77F3A-83A8-4971-AF1D-153286F0EAC9 wds:Q35539318-97FA50C5-CC84-42D5-B2AE-E9FA8E1B4D95 wds:Q35828593-06E849D8-D91B-42DD-BA06-9CF5806F5682 wds:Q39227219-5ED50699-6919-41AE-8BDF-088A29C45A0A wds:Q84513948-59CA820C-81EA-4704-ACA1-9D30EF530F75 wds:Q42790812-F2F37B3C-4967-43FA-B552-ACD1FE424335 wds:Q38772075-0854E8E8-4FF3-4C86-88CB-2428DF582279 wds:Q37020797-045BB0DA-CA9B-4A3B-B409-E033B5931E72 wds:Q37625758-59BDD309-82E5-44FF-A89C-1CA9AB85237D wds:Q36509450-AC82E442-55A0-4CD5-9C83-6FCC3112DF88

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