About: Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart

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About: Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart Goto Sponge NotDistinct Permalink

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scientific article published on 01 October 2012

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в жовтні 2012 (uk) im Oktober 2012 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'ochobre de 2012 (ast) scientific article published on 01 October 2012 (en)
publication date	wds:Q60636832-6ECD91FA-A814-4CA4-93FD-506C4791AEF7
publication date	2012-10-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q60636832-0A5F0D10-B420-47F0-880E-B79F579B57BB wds:Q60636832-0B770E92-6C95-4CDA-AC01-6F860EAC2DA3 wds:Q60636832-0D0AAC6D-5AFC-4D2A-AA1C-951E83A02BB0 wds:Q60636832-0F1BB442-FA48-464A-899E-1049FEDCC74E wds:Q60636832-1419F840-03FE-4859-8A6C-292F4D298B9E wds:Q60636832-2111FEBA-591E-4C7E-965D-8C8D1F733074 wds:Q60636832-38FBF6AE-8773-476F-B487-4F8B4AA1829A wds:Q60636832-39325C9C-D987-48DF-8005-8F94EB8DE408 wds:Q60636832-4302BBE3-4EE5-4058-83C3-B5AB37566906 wds:Q60636832-45362592-C7B8-4AA0-A2C1-3FCDC07AC7A0 wds:Q60636832-49C9D2F2-5A52-4EE8-960F-01D6F990A7C0 wds:Q60636832-4C42F622-0A3C-4185-B33A-37A5C8B70F98 wds:Q60636832-4CB87275-EDC4-4FEA-A43E-CB310B1B1730 wds:Q60636832-4D34266F-6B05-4CB7-949E-176BAED7A770 wds:Q60636832-630F637F-A8CE-4FD1-8284-86C40D92705F wds:Q60636832-6A07E0F0-2706-4E6B-9994-BF1CEB86D364 wds:Q60636832-76ABDA5D-A852-47CC-A554-EADE0F983073 wds:Q60636832-7963784B-D10A-482A-AB4F-20CF4D552737 wds:Q60636832-8292BC06-71A4-41EE-BAAF-621D62EA3CAB wds:Q60636832-940EE1FE-BDBB-4480-B78D-D363F8CFA34A wds:Q60636832-9BDC39FE-745F-4F84-9E5F-DAC19F6EA826 wds:Q60636832-A89853AE-065B-4234-AC6B-D22F103B6EF3 wds:Q60636832-AD1E8E32-F01E-42A3-AE11-9CECE0715F8F wds:Q60636832-B0A48D80-28F1-471F-B1F2-04327EACD404 wds:Q60636832-B4E5CA5C-BD11-40AB-8E0C-EEAFE640DDFB wds:Q60636832-C6B03A64-A3AF-42AC-9473-747127564D52 wds:Q60636832-CCBFB147-3987-45BB-94ED-7533CC960F92 wds:Q60636832-CDF9253F-721A-4E0D-A685-4E073AF4D1A3 wds:Q60636832-CDFCF138-A7C2-4D47-A114-301893FCE024 wds:Q60636832-D63AAF60-0EB0-48AF-8E72-541D87AE3D51 wds:Q60636832-DB6076B3-939F-47BB-8905-64399F551B13 wds:Q60636832-E6D6962B-5676-43C3-BE73-E960C4B016B9 wds:Q60636832-EE452603-9B2F-4E2C-8CAA-B56D64843018 wds:Q60636832-F86FD5D7-7E94-4004-808D-BDB957413981
cites work	SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1 A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes Mitochondrial diseases in man and mouse Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy Metabolic control through the PGC-1 family of transcription coactivators The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy Sirt1 regulates aging and resistance to oxidative stress in the heart Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes Elevated circulating levels of tumor necrosis factor in severe chronic heart failure Sirt1 acts in association with PPAR to protect the heart from hypertrophy, metabolic dysregulation, and inflammation Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1 Myocyte Enhancer Factors 2A and 2C Induce Dilated Cardiomyopathy in Transgenic Mice Dilated cardiomyopathy Inherited cardiomyopathies Transcriptional targets of sirtuins in the coordination of mammalian physiology The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation Regulation of mitochondrial proliferation in the heart: power-plant failure contributes to cardiac failure in hypertrophy Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+-dependent pathway and a reduced mitochondrial protein import MEF2: a central regulator of diverse developmental programs SirT1 regulates energy metabolism and response to caloric restriction in mice SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD. p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts SirT1 in muscle physiology and disease: lessons from mouse models. Alterations in energy metabolism in cardiomyopathies Understanding the impact of mitochondrial defects in cardiovascular disease: a review p300/cAMP-response-element-binding-protein ('CREB')-binding protein (CBP) modulates co-operation between myocyte enhancer factor 2A (MEF2A) and thyroid hormone receptor-retinoid X receptor
author name string	wds:Q60636832-4DD6ED76-5EE9-42E1-918B-FC2C1BB7D001 wds:Q60636832-CC8919FF-E36D-4D65-8F65-DD3FCA5FB2FC wds:Q60636832-D0DCF258-43FC-46A2-90C8-E9B74CB7A6DA wds:Q60636832-E273402A-6B8B-4E00-AD8E-1276978C8AFE
author name string	Iglesias R Ruberte J Dominguez E Planavila A
rdfs:label	Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart (en) Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart (nl)
skos:prefLabel	Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart (en) Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart (nl)
name	Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart (en) Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart (nl)
author	wds:Q60636832-47B556D6-C388-4DEC-B8AD-1D87A4E6D070 wds:Q60636832-818467D0-57B2-4E01-ACEC-74A8AA0CC1DF wds:Q60636832-AE18048E-F70D-456C-B579-13F1437F3817 wds:Q60636832-B216B6F8-DC25-40AA-8FA0-FB943106A1D6 wds:Q60636832-C5B1DA32-9BFB-428F-8D4E-2A3685D74B80
author	Francesc Villarroya Marc Navarro Manlio Vinciguerra Silvia Lope-Piedrafita Marta Giralt

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