About: Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle

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About: Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle Goto Sponge NotDistinct Permalink

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scientific article published on 01 June 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в червні 2000 (uk) article scientifique publié en 2000 (fr) im Juni 2000 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xunu de 2000 (ast) scientific article published on 01 June 2000 (en)
publication date	wds:Q60200108-5996A40C-1F7A-43AD-8A19-359A40B631D5
publication date	2000-06-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q60200108-4B6E53F7-A32B-49E8-B992-CA02E6AF1DC9
language of work or name	English
exact match	wds:Q60200108-68D13442-DF2B-4DDF-B4B0-188B9B650BE7
exact match	https://scigraph.springernature.com/pub.10.1038/sj.onc.1203579
cites work	wds:Q60200108-05253268-37FA-4629-80A2-F7B414DB793E wds:Q60200108-081286E3-3422-498E-8700-26B04294A272 wds:Q60200108-0ABEF7ED-6278-45FE-A229-03506031C651 wds:Q60200108-115DE058-A7B5-4668-B8C2-D3659C7761B7 wds:Q60200108-117BE475-8290-4D42-85E7-982A49F7FD9B wds:Q60200108-16B564DC-01A8-49A6-A25A-6F3FCDCDB43E wds:Q60200108-18EE8486-F828-4ADA-A5A2-4B15F885584C wds:Q60200108-329B26E1-9777-4FC0-B3C5-C55371527A35 wds:Q60200108-355ABC62-6814-433F-8934-AE3493ED0607 wds:Q60200108-40471DDB-BDEF-4B71-8833-0FF6CB1CCF00 wds:Q60200108-439DFD0C-C46C-419F-82CD-18C5BD3F9FB3 wds:Q60200108-471C58A3-C9EA-46F0-A0BF-FCDC7DF18DDA wds:Q60200108-4B0F8056-8AED-4BEB-BD12-C75DE40C55E9 wds:Q60200108-4DE05245-9001-4C0F-B6F9-F3048C0D4160 wds:Q60200108-547371F9-27AE-4DE3-9672-BDE2D6746BE4 wds:Q60200108-56C06FC2-685B-4CFE-BA57-24E4BE785B59 wds:Q60200108-5FD6AF6E-9B82-42EB-B6A3-F416EAEAC728 wds:Q60200108-6D786C35-C68E-42FE-B3BC-8C3712AD7D3B wds:Q60200108-74B83CED-9D5F-49D3-A8D5-25C64D11F367 wds:Q60200108-79569229-038C-409C-A70B-BA3C9EA39BC3 wds:Q60200108-7A277E8E-2E64-4065-B3C4-832EC22C0AC5 wds:Q60200108-868E6DE5-8EE5-4F16-BA48-4E7D043DCF9E wds:Q60200108-8767FD57-25DA-4273-A82E-ADC82FC73E07 wds:Q60200108-8F4002AC-1A87-4859-B0EE-B9795EA47E46 wds:Q60200108-9104BFCF-CAA1-4E51-9CDA-D10BA033104B wds:Q60200108-A6905D50-DB21-428E-BC60-DA8A586CADC4 wds:Q60200108-A7796CFE-68DA-42EE-B923-5B278661DE61 wds:Q60200108-A8D2425B-4F18-4222-8D52-231B275A9ABD wds:Q60200108-AAFB2750-FC6B-4587-BD3A-B1DC08A26556 wds:Q60200108-B8296BBF-5C2A-4085-8445-B6CAA7829F96 wds:Q60200108-BBF098CE-FE09-4AA3-885E-3569BACEB18D wds:Q60200108-C1FEB005-A8B8-4C13-BDC1-3C25EAC68885 wds:Q60200108-C2AC5DCF-5362-4E49-B1D1-34F6DB90A4C4 wds:Q60200108-C7495CBE-7275-4331-B6EA-D1110CABC43D wds:Q60200108-DE099B7D-4BDE-44A3-93D9-4F4597522EDA wds:Q60200108-EABD89F7-BF6A-4D62-8FD4-7BDC852E96E4 wds:Q60200108-F1663055-0A92-41E9-AC59-37D5692F4CF0 wds:Q60200108-F5C47287-78EB-4AE3-824C-4ED5988DB0CC wds:Q60200108-F9A989B9-1971-4245-8E92-46D200797F6E
cites work	Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6 Cancer cell cycles Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4 Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity. Distinct roles for cyclin-dependent kinases in cell cycle control p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase) The ubiquitin-proteasome pathway: on protein death and cell life Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 The tumor suppressor protein p16INK4a. Cyclin E-induced S phase without activation of the pRb/E2F pathway. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a The p16INK4a/CDKN2A tumor suppressor and its relatives. Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. CDK inhibitors: positive and negative regulators of G1-phase progression Monoclonal antibody probes for p21WAF1/CIP1 and the INK4 family of cyclin-dependent kinase inhibitors Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation Cyclin dependent kinase regulation Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16 Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes Cyclin D3: requirement for G1/S transition and high abundance in quiescent tissues suggest a dual role in proliferation and differentiation Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins. Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression The retinoblastoma protein pathway and the restriction point The INK4 family of cell cycle inhibitors in cancer Growth suppression by p16ink4 requires functional retinoblastoma protein p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesis. Mutual requirement of CDK4 and Myc in malignant transformation: evidence for cyclin D1/CDK4 and p16INK4A as upstream regulators of Myc. Immunohistochemical analysis of the D-type cyclin-dependent kinases Cdk4 and Cdk6, using a series of monoclonal antibodies Kip1 meets SKP2: new links in cell-cycle control INK4 cell cycle inhibitors direct transcriptional inactivation of NF-kappaB
author name string	wds:Q60200108-0C59441A-825B-459D-83C2-6A9E4550976E wds:Q60200108-762C8296-93D5-4099-9F1C-6B3282C346A7
author name string	Bartek J Thullberg M
rdfs:label	Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle (en) Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle (nl)
skos:prefLabel	Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle (en) Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle (nl)
name	Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle (en)

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