About: Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours

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About: Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours Goto Sponge NotDistinct Permalink

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scientific article published on 01 June 1999

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в червні 1999 (uk) article scientifique publié en 1999 (fr) im Juni 1999 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xunu de 1999 (ast) scientific article published on 01 June 1999 (en)
publication date	wds:Q59689071-0FCD96B5-B300-4A08-9483-463E949BDFC8 wds:Q59689071-A63FB9FB-8AB0-486A-A5D8-834A5D5C3A2A
publication date	1999-06-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q59689071-01DA1BBE-DCDB-482A-900D-C7200D0ACB56 wds:Q59689071-02BF1213-6607-4A3C-A650-EDEFE6255B2F wds:Q59689071-17D98F8A-D7E1-4904-8FE0-4D6C30BC3B08 wds:Q59689071-44D52E0A-D9CD-47C4-9B20-9B1E8BE892E1 wds:Q59689071-4E3F78C6-B4E2-4ACB-A4D5-2BFABA9E78CA wds:Q59689071-6651AE91-7D97-44ED-A5E1-772D736DE07D wds:Q59689071-86DAA28B-E409-4F98-A5BC-C273C1CCE34C wds:Q59689071-B2EE3A09-46EF-4914-8E3C-6913A293C6C2
author name string	B A Ponder Ami Fishman Bruce A.J. Ponder Lori S. Friedman Patricia A. Harrington Marco Altaras Damon S. Finnigan Lynda G. Bobrow
rdfs:label	Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours (en) Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours (nl)
skos:prefLabel	Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours (en) Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours (nl)
name	Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours (en) Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours (nl)
author	wds:Q59689071-13FCAD5F-10CA-4EE4-9E3A-F8059B355E26 wds:Q59689071-8B391563-5F23-4D55-B600-C1CF75924879 wds:Q59689071-A878BE90-BC96-472F-B022-40A47CDCB935
author	Paul D P Pharoah Susan J. Ramus Simon A Gayther
title	wds:Q59689071-9D65EB18-28CD-42B2-AA5D-66226B9F4004 wds:Q59689071-BFC8EE4B-A2B7-48C2-83A5-BC62B797F029
title	Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours (en) Increased frequency of TP53 mutations in BRCA1 and BRCA2 ovarian tumours (en)
page(s)	wds:Q59689071-7D319741-0B56-4BF1-AD50-29CC83645347
page(s)	91-96
instance of	wds:Q59689071-EB945D04-159A-4ABF-B0D3-CF9A75ADFA3B
instance of	scholarly article
PubMed ID	wds:Q59689071-8F1E26FE-398E-483C-8B4B-A5103A688673
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10337991
PubMed ID	10337991
published in	wds:Q59689071-B9FBECBF-335B-4623-89E7-766B90F87625
published in	Genes, Chromosomes and Cancer
issue	wds:Q59689071-C5BDFAE0-28D4-4140-93E1-2C43F58885B5
volume	wds:Q59689071-5760CA0C-6F45-4E33-9149-EBC4D6617EAC
issue	2
volume	25
DOI	wds:Q59689071-8F493E2D-CD1E-4BDC-AED8-78A7B04E6F2A
DOI	http://dx.doi.org/10.1002/(SICI)1098-2264(199906)25:2%3C91::AID-GCC3%3E3.0.CO;2-5
DOI	10.1002/(SICI)1098-2264(199906)25:2<91::AID-GCC3>3.0.CO;2-5
skos:altLabel	Increased frequency of TP53 mutations in BRCA1 and BRCA2 ovarian tumours (en) Increased frequency of TP53 mutations in BRCA1 and BRCA2 ovarian tumours (nl)
is owl:sameAs of	Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q59689071
is cites work of	Improved survival in women with BRCA-associated ovarian carcinoma Insights into the functions of BRCA1 and BRCA2. Tumor suppressor p53 is required to modulate BRCA1 expression Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma BRCA1 and BRCA2: different roles in a common pathway of genome protection Mutational analysis of TP53 and p21 in familial and sporadic ovarian cancer in Japan. Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas TP53 mutations in familial breast cancer: functional aspects Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes. Recent Advancements in Prognostic Factors of Epithelial Ovarian Carcinoma TP53 and ovarian cancer Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. The mammalian ovary from genesis to revelation A mouse model for the molecular characterization of brca1-associated ovarian carcinoma BRCA1, BRCA2, TP53, and CDKN2A germline mutations in patients with breast cancer and cutaneous melanoma A review of p53 expression and mutation in human benign, low malignant potential, and invasive epithelial ovarian tumors BRCA1 and implications for response to chemotherapy in ovarian cancer Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53. DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2. The role of BRCA1 in homologous recombination repair in response to replication stress: significance in tumorigenesis and cancer therapy Brca2 deficiency leads to T cell loss and immune dysfunction p53 inactivation is a rare event in familial breast tumors negative for BRCA1 and BRCA2 mutations. Comparative genomic hybridization in inherited and sporadic ovarian tumors in Israel BRCA mutations in the manifestation and treatment of ovarian cancer. Therapy-related myeloid neoplasms: when genetics and environment collide Analysis of mutation, selection, and epistasis: an informed approach to cancer clinical trials. Skin cancer risk in BRCA1/2 mutation carriers Homologous Recombination and Replication Fork Protection: BRCA2 and More! Selective loss of chromosome 11 in pheochromocytomas associated with the VHL syndrome Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers Killing the umpire: cooperative defects in mitotic checkpoint and BRCA2 genes on the road to transformation Genetic factors in ovarian carcinoma BRCA2 and TP53 collaborate in tumorigenesis in zebrafish Conditional knockout of brca1/2 and p53 in mouse ovarian surface epithelium: do they play a role in ovarian carcinogenesis? Clinicopathological significance of GADD45 gene alterations in human familial breast carcinoma

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