About: Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats

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scholarly article by Zhengyi He published in December 2018

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 2018 (uk) article scientifique publié en 2018 (fr) im Dezember 2018 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Zhengyi He published in December 2018 (en)
publication date	wds:Q59329042-09484385-EC9A-468E-8FFB-BD5DCDDB1AFA
publication date	2018-12-21 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q59329042-BBF732DF-E0E6-43A8-90B3-49E84D7E04A5
language of work or name	English
cites work	wds:Q59329042-13D43B74-F387-434D-8D1B-765BE38AA02B wds:Q59329042-2A396FD7-B687-414F-AB18-41DD16DBCDAC wds:Q59329042-417286A4-26AB-4C6F-90D3-627F238CD937 wds:Q59329042-43075B0D-AEB4-4AEA-B6D4-624209F69613 wds:Q59329042-43A06C8D-1F38-4C22-884C-F34B376E0553 wds:Q59329042-4B3F9625-D764-4341-8058-4114BC6C94D2 wds:Q59329042-50ED45D8-A7EA-45C6-B382-31D903767F5C wds:Q59329042-6C55C749-5369-46CE-B573-83EAE078D57F wds:Q59329042-772E34C9-3467-418B-B85A-7570230A1A20 wds:Q59329042-858D0AF5-EF86-4ADA-BCFA-73559C031ED4 wds:Q59329042-A062A076-6289-415E-B727-D37092C84F91 wds:Q59329042-B909B59F-80A8-4904-92CE-E7D9ECB3C841 wds:Q59329042-C418E771-4590-4657-9A39-875FA824A740 wds:Q59329042-C594C817-FC24-4997-897C-FF264F7BC502 wds:Q59329042-C88F29BB-033C-4A3D-B099-2467EEE01CEA wds:Q59329042-DD44686C-B09F-48A9-970D-50CED6672C8C wds:Q59329042-E750BF25-A0C7-4D3E-99F6-662BA94A803F wds:Q59329042-EABD1B74-6958-4D22-8F50-9099C09820D8 wds:Q59329042-F2459D3F-B08D-49B4-9123-AD02A2B2C9DF
cites work	Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids. Myostatin: a novel insight into its role in metabolism, signal pathways, and expression regulation High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects. Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways Development and applications of CRISPR-Cas9 for genome engineering Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing. Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors. Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle Genetic screens in human cells using the CRISPR-Cas9 system In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9 A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs Efficient Generation of Myostatin Gene Mutated Rabbit by CRISPR/Cas9. Inhibition of myostatin in adult mice increases skeletal muscle mass and strength Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system. Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice Creatine supplementation in the aging population: effects on skeletal muscle, bone and brain PROTEIN UTILIZATION IN RUMINANTS. I. BLOOD UREA NITROGEN AS AFFECTED BY PROTEIN INTAKE Role of myostatin in metabolism
author name string	wds:Q59329042-249AFCCC-87EC-4896-8DB8-5F4A95C0BD24 wds:Q59329042-27686672-561A-4236-9D9E-5C3376A12C28 wds:Q59329042-48D08756-6714-4EB3-9651-2E61D5B57DBE wds:Q59329042-B3596C3B-D74C-44FA-80AC-20A8BA03206E wds:Q59329042-BBEA0B58-0385-4925-8E40-3CED17F10833 wds:Q59329042-D32089BF-00AB-428B-83E6-7136509DD8A0 wds:Q59329042-D76A42F0-3CB4-4D01-9D3A-98762E47D919
author name string	Lei Jiang Ting Zhang Yong Cheng Daijin Wu Minya Zhou Zhengyi He Junyan Mei
rdfs:label	Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats (en) Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats (nl)
skos:prefLabel	Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats (en) Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats (nl)
name	Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats (en) Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats (nl)
title	wds:Q59329042-D14780EE-FE7E-4C48-AEED-CF6741A7A045
title	Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats (en)
page(s)	wds:Q59329042-6931DE7B-80CF-4067-B62C-EED37DD7B043
page(s)	BSR20180742
instance of	wds:Q59329042-D9C97CA7-A90B-4D0C-B126-E0DB94343E49
instance of	scholarly article
main subject	wds:Q59329042-1A5052B4-569C-439E-824D-DE5A618EB410 wds:Q59329042-336D1F43-2F09-4492-8458-F681084012FE wds:Q59329042-3417B1E2-C08C-467A-B71E-49CB7BB8A68A wds:Q59329042-3AAB7176-DA61-4AD1-9009-733CDA13E35C wds:Q59329042-C026A2BA-21F7-47D0-ABA4-EF7A214405E4 wds:Q59329042-C5DA99F9-B775-4D50-AD8B-525E972F4F3F
main subject	zygote CRISPR phenotype biophysics molecular biology Cas9
PubMed ID	wds:Q59329042-52D378C9-5084-4EFE-90D8-F9F7736DF446
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30201688
PubMed ID	30201688
published in	wds:Q59329042-7DEFDC23-51E2-4812-AAE7-24FF78C7E2AC
published in	Bioscience Reports
issue	wds:Q59329042-3F1E60C1-0970-49FC-B6B2-9715FB90CA2A
volume	wds:Q59329042-69CBAC4F-22FB-42EB-9C30-FF023CFD8E22
issue	6
volume	38
DOI	wds:Q59329042-B5F3F95E-5137-4D91-95FA-F8650D29FBF2
DOI	http://dx.doi.org/10.1042/BSR20180742
DOI	10.1042/BSR20180742
copyright license	wds:Q59329042-b055a1b7-160f-4f04-bd7a-f5b9d53d1721
copyright status	wds:Q59329042-05629718-02c2-4eb7-ae1d-cf93d7096f8c

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