About: Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

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scientific article published in Nature

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rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) article publié dans la revue scientifique Nature (fr) scientific article published in Nature (en) im Februar 1989 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в Nature в лютому 1989 (uk)
publication date	wds:Q59098044-43DDF653-AA92-450D-B055-E4D56EC465F0
publication date	1989-02-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q59098044-9687D56D-F66F-4075-9D43-30AD92F4781E
language of work or name	English
exact match	wds:Q59098044-82EEA95D-0080-470A-BC2F-C2A8D772AA0A
exact match	https://scigraph.springernature.com/pub.10.1038/337562a0
cites work	wds:Q59098044-03704A18-C000-44DE-8B33-E4A88602783D wds:Q59098044-33E5B523-293D-4A86-855D-96259C28D0B4 wds:Q59098044-342D5067-ED02-4F88-886D-95AD0A61AE89 wds:Q59098044-345D8308-28F9-4FD6-AA4C-6055484AFCA4 wds:Q59098044-444A0831-6615-4498-95DF-9F1505D98FE2 wds:Q59098044-509382F2-48A8-425C-9016-DF285B82EFE4 wds:Q59098044-57699369-D3C5-44B5-92EE-DA95D5D8D1C5 wds:Q59098044-6A6A6165-3B75-454A-9003-60AB0EF6434A wds:Q59098044-76C54D5B-8F0B-4174-A769-44BC81DE43A5 wds:Q59098044-7AD5EA77-F2EE-42B2-AE25-0B909F6EEFA4 wds:Q59098044-82538659-6019-4C1C-B0C5-B6E557564274 wds:Q59098044-954C95C0-C0A9-4DF2-BFA2-AEBCAD6D6B92 wds:Q59098044-95D39A3A-E7B6-4306-B0E8-7BE40C7C8095 wds:Q59098044-A707E2CC-3BDB-42EA-B0DA-15E2DE5ABBD0 wds:Q59098044-BFD7586A-D5F5-49CE-B668-F146E40DF27C wds:Q59098044-DB846647-DD62-40E4-9B1C-51A46D73EC15 wds:Q59098044-DFCE6790-B9BB-4EC4-ABDD-8160ECA0A4E5 wds:Q59098044-F6086E80-925D-4DC1-A59A-D0173FD15D08
cites work	Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively A natural model of immunologic tolerance. Tolerance to murine C5 is mediated by T cells, and antigen is required to maintain unresponsiveness T cell tolerance by clonal elimination in the thymus 5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes The autoantigen-binding B cell repertoires of normal and of chronically graft-versus-host-diseased mice Spleen cells from animals tolerant to a thymus-dependent antigen can be activated by lipopolysaccharide to synthesize antibodies against the tolerogen Induction of tolerance in athymic mice with an antigen which is highly immunogenic in euthymic mice Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs Analysis of an evolutionarily conserved antigenic site on mammalian cytochrome c using synthetic peptides Receptor-mediated inactivation of early B lymphocytes Tolerance as an active process Transgenic mice with immunoglobulin genes Kinetic Differences in Unresponsiveness of Thymus and Bone Marrow Cells Relative sensitivity of fetal and newborn mice to induction of hapten-specific B cell tolerance Quantitative evidence against inactivation of self-reactive B-cell clones
author name string	wds:Q59098044-15045F43-8A04-42EA-92A2-F73B61033B7D
author name string	Bürki K
rdfs:label	Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes (en) Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes (nl)
skos:prefLabel	Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes (en) Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes (nl)
name	Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes (en) Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes (nl)
author	wds:Q59098044-A28CB54C-F651-4ADE-950C-92BFDD04FF51
author	David Nemazee
title	wds:Q59098044-DB226F0B-F962-44A5-8266-E0F423DFB07E
title	Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes (en)
page(s)	wds:Q59098044-08382460-CF69-4663-B706-391F9E90E93F
page(s)	562-566
instance of	wds:Q59098044-DAFD52EC-361E-4B8E-A443-C33C79176C3A
instance of	scholarly article
main subject	wds:Q59098044-E2AF4ED6-5C92-41B7-A688-80AC30ECDCD6
main subject	antibody
PubMed ID	wds:Q59098044-F8D064B2-44E4-4224-B8D8-C83853EA1E2E
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2783762
PubMed ID	2783762
published in	wds:Q59098044-32AA6E97-88BE-48BA-B642-2E6C1F051126
published in	Nature
issue	wds:Q59098044-7F8606C3-2C01-487F-BB47-9192AC51FCF5
volume	wds:Q59098044-9ABCAF9D-07F7-40AE-A637-DF0E962734A3
issue	6207
volume	337
DOI	wds:Q59098044-ED6EC023-28D5-4444-991F-32A8C4F2BCB5
DOI	http://dx.doi.org/10.1038/337562A0
DOI	10.1038/337562A0
Dimensions Publication ID	wds:Q59098044-13A1E1FE-631E-4EB8-95D4-55E1F3AB129B
Dimensions Publication ID	1034366827
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q59098044
is cites work of	Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate Receptor editing is the main mechanism of B cell tolerance toward membrane antigens Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive. MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells Editing anti-DNA B cells by Vlambdax Defective B cell tolerance checkpoints in systemic lupus erythematosus Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Maintenance of tolerance by regulation of anti-myeloperoxidase B cells. The central and multiple roles of B cells in lupus pathogenesis CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity Virus-like particles: flexible platforms for vaccine development Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A Requirement for Rictor in homeostasis and function of mature B lymphoid cells.

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