About: Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA

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scientific article published in Nature

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) article publié dans la revue scientifique Nature (fr) scientific article published in Nature (en) im Mai 1994 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в Nature в травні 1994 (uk)
publication date	wds:Q59095509-00648BD3-9BA9-474B-AC42-ACF8A5C25896
publication date	1994-05-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q59095509-C9877DB2-AC28-4954-992A-8085C711E93C
language of work or name	English
exact match	wds:Q59095509-502FDFEB-0532-4C6A-B204-0FC83749EA38
exact match	https://scigraph.springernature.com/pub.10.1038/369239a0
cites work	wds:Q59095509-1211FC03-7CC1-41D4-968E-B4D6B5AF3AFE wds:Q59095509-1275C7B4-0D21-448D-862A-26AB1B715EE0 wds:Q59095509-1D06B410-86C3-4955-A4BA-7265E2E5E82E wds:Q59095509-1DA939E9-F832-4189-91FB-3497955EFCE6 wds:Q59095509-24CFC630-06C9-4556-8865-195C2EEAB819 wds:Q59095509-3562F21E-5E53-4E54-BBAF-31563D5EAC77 wds:Q59095509-386CADDF-83B1-4B00-A9E6-F367E77271EB wds:Q59095509-3A57ED3B-BDDF-4FF4-B132-6CD6594109FF wds:Q59095509-3AEB8083-D2DF-49FC-B6C9-E378F0DD8DE6 wds:Q59095509-3F8DC220-EB08-4E41-90FB-9F5966192C7E wds:Q59095509-6649EF17-11F8-4F27-BD6D-6B4B329D6E3C wds:Q59095509-6A121B45-B5D8-4688-9324-DD1162ACB04E wds:Q59095509-7999D0AE-1DCC-48EE-BB25-DAA470C17F4B wds:Q59095509-9DC1956D-02FE-4A66-94D8-BB9C1E564222 wds:Q59095509-A0F5FBA5-8D85-4C32-ABEE-57A850F8DFC6 wds:Q59095509-A13EC188-452E-4F17-A0A6-85BE7353C426 wds:Q59095509-A5472747-2134-4175-91B8-6E4AB1D7F8A0 wds:Q59095509-AFEB4754-0C30-41BC-A8D9-E340A0AD136D wds:Q59095509-CBDF1C93-2082-4B93-8DDF-FBFEF0EF576E wds:Q59095509-D4702FD9-D1D6-4650-A6FB-1612F824AD80 wds:Q59095509-E9B85D7C-2433-49A4-921D-E8A219280E80 wds:Q59095509-FB7480C6-E99D-479A-9D52-998CD827F96C wds:Q59095509-FF4F4D3A-7420-43B7-BAD9-6DB861C0A857
cites work	The mechanism of action of cyclosporin A and FK506 Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction FK506 and cyclosporin, molecular probes for studying intracellular signal transduction Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activation Cloning and nucleotide sequence of the murine interleukin-3 gene Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells Hygromycin B Phosphotransferase as a Selectable Marker for DNA Transfer Experiments with Higher Eucaryotic Cells The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin cDNA cloning of murine interleukin-HP1: homology with human interleukin 6. Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor. Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription Regulation of interleukin 3 mRNA expression in mast cells occurs at the posttranscriptional level and is mediated by calcium ions Tumor suppression involves down-regulation of interleukin 3 expression in hybrids between autocrine mastocytoma and interleukin 3-dependent parental mast cells Suppressible and nonsuppressible autocrine mast cell tumors are distinguished by insertion of an endogenous retroviral element (IAP) into the interleukin 3 gene A v-H-ras-dependent hemopoietic tumor model involving progression from a clonal stage of transformation competence to autocrine interleukin 3 production Spontaneous, in vitro, malignant transformation of a basophil/mast cell line Differential inhibition by cyclosporin A reveals two pathways for activation of lymphokine synthesis in T cells
author name string	wds:Q59095509-20EE8FF3-B4B2-4022-A09A-AF9F86040C45 wds:Q59095509-4D4C3BF2-8498-4DEB-849E-6856C4F1463A wds:Q59095509-4DC420F6-FCEA-4BEF-894B-E1F231C877CE wds:Q59095509-638008FD-F042-493E-AC3E-9F581A0EAE9D wds:Q59095509-DB863821-BDA6-45FA-B118-AEB975E2ADF4
author name string	Hahn S Moroni C Hirsch HH Nair AP Banholzer R
rdfs:label	Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA (en) Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA (nl)
skos:prefLabel	Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA (en) Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA (nl)
name	Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA (en) Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA (nl)
title	wds:Q59095509-4255A9C2-D2F7-4EA7-A030-F6DB6E00D726
title	Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA (en)
page(s)	wds:Q59095509-3B022347-6392-4AA8-ADB5-DE1C4D9ACE2C
page(s)	239-242
instance of	wds:Q59095509-C4849167-A877-449A-8D9E-14537DBDC05E
instance of	scholarly article
main subject	wds:Q59095509-4DED5C69-54F4-4860-ACC0-3F9C82E35DFD wds:Q59095509-7bca4398-b951-42c7-8a2d-d5bf9a7167da
main subject	interleukins cyclosporine
PubMed ID	wds:Q59095509-5E2EBD43-4820-4953-A699-CAF9AA9B20BF
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8183344
PubMed ID	8183344
published in	wds:Q59095509-3E02BD58-9145-47CC-9A72-2A68F42B96C8
published in	Nature
issue	wds:Q59095509-4E2CE35A-6CFF-4008-B375-83B098430406
volume	wds:Q59095509-C4159F2E-1A75-4AD0-BD9B-58564E5EF4C2
issue	6477
volume	369
DOI	wds:Q59095509-E6515D6B-5297-4798-9526-6E9E2911FBD8
DOI	http://dx.doi.org/10.1038/369239A0
DOI	10.1038/369239A0
Dimensions Publication ID	wds:Q59095509-CAB84B90-88F1-46B6-86F6-EA5AB6E9411E
Dimensions Publication ID	1011253819
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q59095509

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