About: GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells

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scientific article published in Nature

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) article publié dans la revue scientifique Nature (fr) scientific article published in Nature (en) im Juni 2018 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в Nature в червні 2018 (uk)
publication date	wds:Q59080964-2EA21636-57A7-48A9-95C6-EA2D123144BA
publication date	2018-06-06 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q59080964-FB510EB5-38F0-4306-97F6-9343AC529A1D
language of work or name	English
exact match	wds:Q59080964-465A184D-ECCC-4168-A5CD-B6FA4EDC4FE8
exact match	https://scigraph.springernature.com/pub.10.1038/s41586-018-0190-3
cites work	wds:Q59080964-0156BA64-8054-44A1-94D6-230085105C90 wds:Q59080964-0A1B9FAE-3225-4F9A-B887-227C231701F7 wds:Q59080964-18BF6522-CCFE-401C-B98D-39749C72601E wds:Q59080964-216DBE55-E14F-41D8-8626-26315863418D wds:Q59080964-25150CCD-302B-40ED-B7D3-FCCE9E2A4B6A wds:Q59080964-28FDBAE5-D4FD-4C8E-A280-1B5D1C4998D9 wds:Q59080964-3331E568-BC64-40F2-8284-A8255218693F wds:Q59080964-3663F4E6-6E07-4325-91A6-32FEDF0131C0 wds:Q59080964-366F2730-EBD8-43C9-B3ED-A286029C9DE0 wds:Q59080964-459CDBE4-68AF-42C7-9F9F-702D62353D15 wds:Q59080964-4D1896CA-6B97-4D3F-B62C-239527223626 wds:Q59080964-5025FAFB-0FA2-42BA-A73B-EE10AD866D53 wds:Q59080964-50DCB347-C78C-43C9-8C5C-7F4A45068749 wds:Q59080964-55B22E44-5D25-44C2-B576-3C8E089E5AF6 wds:Q59080964-5DE98AC2-7A3E-4E5E-8B9B-3198197EBAB4 wds:Q59080964-6B4724E4-5D6C-479D-A4B0-D1282FB9850D wds:Q59080964-7D867FB3-1D09-43F7-93D3-7B33AB3AF81F wds:Q59080964-7E66C00B-31DB-4DDF-AAA9-A78C703ECF29 wds:Q59080964-80FBC179-F25A-4C56-8B0A-0458F971BB5D wds:Q59080964-871AA266-1B1F-4E97-BC7A-D6D049A09F93 wds:Q59080964-A12E506E-59F2-40B9-8F79-9EAFE4F79CF0 wds:Q59080964-B128B2C6-0A1C-4B42-8400-B6429DC8685D wds:Q59080964-BEB98C1C-56D8-4634-884B-FAEB9FBFC1FF wds:Q59080964-BFA6D05D-5185-4BE0-B64A-2A37C0AEA416 wds:Q59080964-C1B784C9-242E-47D4-AB70-AE8510E4E697 wds:Q59080964-C5701CB9-4F2A-41F8-A9A0-8DE51D6699EF wds:Q59080964-CAD98F05-9BCF-41B0-A562-A2C283754201 wds:Q59080964-D893235E-6095-4FEE-A81E-113214AB4D73 wds:Q59080964-EBEFB4B8-A428-4A1D-A190-FD9846CC8358
cites work	Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells. Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis. Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning Primary mouse small intestinal epithelial cell cultures Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells A robust and high-throughput Cre reporting and characterization system for the whole mouse brain Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis. Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1). Tissue-specific and inducible Cre-mediated recombination in the gut epithelium Evolutionary Divergence of Platelet-Derived Growth Factor Alpha Receptor Signaling Mechanisms The stem-cell niche as an entity of action Identification of stem cells in small intestine and colon by marker gene Lgr5 Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow. Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells. Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease Foxl1-expressing mesenchymal cells constitute the intestinal stem cell niche Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts Visualization of a short-range Wnt gradient in the intestinal stem-cell niche. Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury. Wnt Ligands as a Part of the Stem Cell Niche in the Intestine and the Liver.
author name string	wds:Q59080964-05A778C6-16B7-4D83-B13E-58BC5A27FF92 wds:Q59080964-55B3EF30-12A4-4B4C-9852-8A9A3EA35FA9 wds:Q59080964-D957645C-229A-4459-B3DA-1778ED48C92C
author name string	George Hausmann Slavica Dimitrieva Bahar Degirmenci
rdfs:label	GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells (en) GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells (nl)
skos:prefLabel	GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells (en) GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells (nl)
name	GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells (en) GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells (nl)
author	wds:Q59080964-421C6D10-B4EE-4BEF-89DA-CB0251B02503 wds:Q59080964-A29E2010-7A28-4DC3-940C-6E289096444F
author	Konrad Basler Tomas Valenta
title	wds:Q59080964-CF5009F1-2D09-430C-ACB9-C97063699D6E
title	GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells (en)
page(s)	wds:Q59080964-E5F4244C-A895-45FD-907A-A42BC8BCF70C
page(s)	449-453
instance of	wds:Q59080964-07530298-951F-473C-90EC-67723D4EF035
instance of	scholarly article
PubMed ID	wds:Q59080964-D0072D90-C894-41B5-A93F-0DF7913C73CE
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/29875413
PubMed ID	29875413
published in	wds:Q59080964-1C470703-EEC9-484F-A74B-B87E346E8E7A
published in	Nature
issue	wds:Q59080964-FBA952F6-9A66-4232-BBE5-EF0F03F52B19
volume	wds:Q59080964-E6AABC0C-20B4-4EAF-A43F-BC5605709BE8

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