About: Human γ-globin genes silenced independently of other genes in the β-globin locus

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scientific article published in Nature

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) article publié dans la revue scientifique Nature (fr) scientific article published in Nature (en) im März 1991 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в Nature в березні 1991 (uk)
publication date	wds:Q59064800-7945A2B9-3AF8-4D88-AF5E-9F47B655B64C
publication date	1991-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q59064800-DE050B6C-3D17-40A8-965E-6CB3C3F8AD06
language of work or name	English
exact match	wds:Q59064800-5366F369-9BFE-4A2E-AD6D-F059AE0B3312
exact match	https://scigraph.springernature.com/pub.10.1038/350252a0
cites work	wds:Q59064800-094CC644-2C50-4C05-A30C-B6478B325A5E wds:Q59064800-3BEA3182-86E7-4624-900B-D2281453B1B1 wds:Q59064800-42483C8F-44C2-494C-A5C1-9AF1E24C3C0C wds:Q59064800-501E7BEC-6C77-475F-9365-5358B5EAC8C9 wds:Q59064800-7AB71971-EF4B-4A11-9A1F-E8AB30DFD5C7 wds:Q59064800-7C9FDC81-FDE7-4E7E-8E69-17DC5277BAD2 wds:Q59064800-935744EE-3E5B-4B8A-B12B-79FB4EF53D70 wds:Q59064800-99B3E390-99D6-49B9-84FC-191D06190169 wds:Q59064800-A64F5DE0-0EC1-4775-893A-9AD99F77CC41 wds:Q59064800-A6E96D80-F700-435F-AED0-147874C9E95D wds:Q59064800-B63A4997-9503-45AD-B142-993316C9E22B wds:Q59064800-FA3593F0-5DAA-4F32-B74B-6DD2F61B11CA
cites work	An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice. Human gamma- to beta-globin gene switching in transgenic mice. Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse Detailed analysis of the site 3 region of the human beta-globin dominant control region Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice Position-independent, high-level expression of the human beta-globin gene in transgenic mice Human globin locus activation region (LAR): role in temporal control Molecular analysis of the human beta-globin locus activation region Developmentally regulated and erythroid-specific expression of the human embryonic beta-globin gene in transgenic mice An in vitro globin gene switching model based on differentiated embryonic stem cells
author name string	wds:Q59064800-F6D55085-A5B0-4702-93E9-EF0A06758078 wds:Q59064800-F9785FF5-730D-41A1-AA9A-487F0224DA26
author name string	Grosveld F Dillon N
rdfs:label	Human γ-globin genes silenced independently of other genes in the β-globin locus (en) Human γ-globin genes silenced independently of other genes in the β-globin locus (nl)
skos:prefLabel	Human γ-globin genes silenced independently of other genes in the β-globin locus (en) Human γ-globin genes silenced independently of other genes in the β-globin locus (nl)
name	Human γ-globin genes silenced independently of other genes in the β-globin locus (en) Human γ-globin genes silenced independently of other genes in the β-globin locus (nl)
title	wds:Q59064800-919ACD10-CFB3-448E-9625-F576F9C98338
title	Human gamma-globin genes silenced independently of other genes in the beta-globin locus (en)
page(s)	wds:Q59064800-AA9D956E-3614-4651-9095-A4D5DC6BC327
page(s)	252-254
instance of	wds:Q59064800-4E5FDA5C-5D2E-4BEB-8CAD-B89C697700C4
instance of	scholarly article
PubMed ID	wds:Q59064800-94194F80-171A-4B0E-93FC-526BA622EE22
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/1706482
PubMed ID	1706482
published in	wds:Q59064800-7E0734EF-C269-449E-ABAC-98BBEE700523
published in	Nature
issue	wds:Q59064800-FD54B24F-0FD7-4938-B910-C23D63A70F0E
volume	wds:Q59064800-F99A4953-AF90-4336-BF0A-A01620DDFDB9
issue	6315
volume	350
DOI	wds:Q59064800-8165447D-524D-42FB-86B6-AEA14494FF59
DOI	http://dx.doi.org/10.1038/350252A0
DOI	10.1038/350252A0
Dimensions Publication ID	wds:Q59064800-54DDE041-252A-41B2-9666-0EE945338D04
Dimensions Publication ID	1026007026
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q59064800
is cites work of	The erythroid Krüppel-like factor transactivation domain is a critical component for cell-specific inducibility of a beta-globin promoter Developmentally programmed rearrangement of T cell receptor Vgamma genes is controlled by sequences immediately upstream of the Vgamma genes Chromatin interaction mechanism of transcriptional control in vivo Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression Transcription complex stability and chromatin dynamics in vivo. Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants Neurons differentially control expression of a herpes simplex virus type 1 immediate-early promoter in transgenic mice. Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes Beta-globin regulation and long-range interactions Mutation of gene-proximal regulatory elements disrupts human epsilon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic mice Regulation of globin gene expression in erythroid cells. Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3. Phylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human gamma and epsilon globin genes Repression of human gamma-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter The role of p22 NF-E4 in human globin gene switching Factors and forces controlling V(D)J recombination Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights Methylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression Induction of Fetal Hemoglobin In Vivo Mediated by a Synthetic γ-Globin Zinc Finger Activator Activation of the beta-globin locus control region precedes commitment to the erythroid lineage A DNA-binding factor in adult hematopoietic cells interacts with a pyrimidine-rich domain upstream from the human delta-globin gene Erythropoiesis: development and differentiation A dominant chromatin-opening activity in 5' hypersensitive site 3 of the human beta-globin locus control region Negative regulation of transcription in eukaryotes Recombinant human hemoglobins designed for gene therapy of sickle cell disease An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer T to C substitution at -175 or -173 of the gamma-globin promoter affects GATA-1 and Oct-1 binding in vitro differently but can independently reproduce the hereditary persistence of fetal hemoglobin phenotype in transgenic mice Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site. Differential binding of the NFE3 and CP1/NFY transcription factors to the human gamma- and epsilon-globin CCAAT boxes. Transcriptional control of globin gene switching during vertebrate development Altered regulation of beta-like globin genes by a redesigned erythroid transcription factor Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

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