About: Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

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About: Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b Goto Sponge NotDistinct Permalink

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scientific article published in Nature

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im Johr 2000 veröffentlicht worden isch (gsw) article publié dans la revue scientifique Nature (fr) im Jahr 2000 veröffentlichter wissenschaftlicher Artikel (de) scientific article published in Nature (en) наукова стаття, опублікована в Nature в січні 2000 (uk)
publication date	wds:Q59058408-054DCFE4-0C93-4B57-8059-A7AD18DF82AC
publication date	2000-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q59058408-2195D1D0-C777-4F20-9AEF-C701CFCC8610
language of work or name	English
exact match	wds:Q59058408-71DC6113-5B61-4D67-BAA1-0A60F7C69735
exact match	https://scigraph.springernature.com/pub.10.1038/35003228
cites work	wds:Q59058408-18834B9B-8195-4542-8622-5EE7AE229CD4 wds:Q59058408-22672AAC-F4CE-46F2-BC14-26BDD6DB2182 wds:Q59058408-3576E77F-BBA8-4EDA-9F89-74839EE5CF99 wds:Q59058408-586D3DFE-9152-461C-8CA9-AFF2CA235832 wds:Q59058408-5BC82382-5A17-4990-B509-F480274DE736 wds:Q59058408-62B3B7BF-0413-447F-85E3-AADC18660C15 wds:Q59058408-6E4FEB70-B145-4E64-8975-CF6C5489D195 wds:Q59058408-719541CA-7363-45BC-821B-11A61052B8E4 wds:Q59058408-74AB73DF-4C59-4E1B-9250-76547CBAFB67 wds:Q59058408-76A38D63-B623-4994-89FB-06CA1FAF60A7 wds:Q59058408-787B13CF-99DF-4D0E-B8A4-636E23FA2112 wds:Q59058408-88BB6764-F4E0-4EA5-8B12-D6628B2801DD wds:Q59058408-8A835AF0-41FD-4597-ABB2-44CDE939EBFA wds:Q59058408-A839D8A0-384D-4BFD-91D3-72B304A69A7F wds:Q59058408-B2182713-8EFF-4170-922C-D3B88F1364E0 wds:Q59058408-BB48C90A-453E-4F14-9F23-CF7E2DEEB8CB wds:Q59058408-BC64994F-A1AE-4C9A-A90B-289EDE571F45 wds:Q59058408-CDA2E82C-81AD-4D93-8AA0-2BCA71581D65 wds:Q59058408-DA70B24E-CAA2-4931-8ABE-8E1B4F94035A wds:Q59058408-E15D21E5-934B-4F3A-890D-0B2C19600888
cites work	Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation Positive versus negative signaling by lymphocyte antigen receptors B lymphocytes express and lose syndecan at specific stages of differentiation Altered thymic positive selection and intracellular signals in Cbl-deficient mice Functional management of an antiviral cytotoxic T-cell response Chronic inflammation caused by lymphotoxin is lymphoid neogenesis Cbl-b regulates the CD28 dependence of T-cell activation. Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation. Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells Adaptors and molecular scaffolds in immune cell signaling The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase Primate evolution--in and out of Africa CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones Differential T cell costimulatory requirements in CD28-deficient mice Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice. Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance Binding of T cell receptor to major histocompatibility complex class II-peptide complexes at the single-cell level results in the induction of antigen unresponsiveness (anergy)
author name string	wds:Q59058408-0D1FBA94-4848-4244-8E01-2C9E482C6CE5 wds:Q59058408-250C8841-59CE-47E4-A4BB-155D8F42FF72 wds:Q59058408-3309DADF-E231-4815-BAD3-A92D46867A22 wds:Q59058408-4462B250-BE53-42C0-85BC-FBD764499932 wds:Q59058408-4658CC4E-25B4-4B16-B933-B429712199BC wds:Q59058408-4D9030D1-1D9F-4241-AB96-D0C431B5F535 wds:Q59058408-54415006-FE3B-4C01-AF3A-2C0CA5E2E658 wds:Q59058408-799BC4EA-8C1D-4B0D-B747-A09538F13641 wds:Q59058408-AE724B5B-6A53-4516-AFF1-B3003BE929C6 wds:Q59058408-D320EB43-3CAC-40EE-9565-6E8F0471DF0C wds:Q59058408-D7B19891-F5A9-4DE3-828A-452A8EBCCD9D wds:Q59058408-D7BD149F-CF44-4BDF-BDB2-4BB2D6D740FB wds:Q59058408-E1A607F1-9C65-4FD0-98CD-811DE7810560 wds:Q59058408-EF773A4B-A16A-4BF3-A071-FDAC8BE5BB85 wds:Q59058408-F5ABBD29-1AD2-487B-ADC2-0DE3E6E24AF4
author name string	Y Y Kong T Sasaki J Le A Wakeham J M Penninger I Sarosi H Nishina D Bouchard K Bachmaier S Lipkowitz C Krawczyk S Mariathasan I Kozieradzki A Itie A Oliveira-dos-Santos
rdfs:label	Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b (en) Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b (nl)
skos:prefLabel	Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b (en) Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b (nl)
name	Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b (en) Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b (nl)
author	wds:Q59058408-7370D88D-F831-4FB0-A41E-A612D62A2BFE
author	Pamela Ohashi
title	wds:Q59058408-2D463C0B-EED2-485C-B810-118982BFB32A
title	Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b (en)
page(s)	wds:Q59058408-6EF7768E-6AC4-4AFC-B8AD-019A32890829
page(s)	211-216
instance of	wds:Q59058408-1B90B6C6-D859-4BA4-8D00-204B9AF3030B
instance of	scholarly article
PubMed ID	wds:Q59058408-FF00CD61-749B-4CCE-983D-85C12C36A88A
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10646608

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