About: Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

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scientific article published on 26 December 2004

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2004 (fr) наукова стаття, опублікована в грудні 2004 (uk) im Dezember 2004 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 2004 (ast) scientific article published on 26 December 2004 (en)
publication date	wds:Q58862256-C4C15B3D-56F0-4F2D-8A74-C207E3709363
publication date	2004-12-26 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q58862256-85E1B005-890F-42EF-BFDB-CF5C05AD4D5C
language of work or name	English
exact match	wds:Q58862256-8CBAB6F5-7AB5-419C-B4ED-124DE3297BB4
exact match	https://scigraph.springernature.com/pub.10.1038/nm1160
cites work	wds:Q58862256-0C8D2962-A493-49E7-BA4A-8D6CBC340740 wds:Q58862256-0FF38287-00FB-48BF-9D46-D03E87E5C704 wds:Q58862256-135E1DB8-6028-4AF4-BB62-DF8FE38EA667 wds:Q58862256-14DA4888-5024-406B-AC87-EF71160DD5B4 wds:Q58862256-1C20F553-8C55-4C30-A661-12276FC3D193 wds:Q58862256-2E998688-3061-432A-847A-66AF148E93B5 wds:Q58862256-3431E970-9229-4AEF-B562-77CDC935C325 wds:Q58862256-3635A040-E36A-4F4E-B5D1-5659823F125C wds:Q58862256-3F799098-E734-4969-8808-7868008AC81E wds:Q58862256-4B5FA78B-061C-4998-8998-E59D99795742 wds:Q58862256-6E1D3EDE-4FD1-435A-BBA0-A74FB16B7269 wds:Q58862256-6F5E4DA7-A74F-4A62-B315-1D44E6368D4C wds:Q58862256-7760F667-4E3F-4FC2-8F01-9F5F30CC07CC wds:Q58862256-7CCE230F-447D-40CC-9BD4-5EBC0790D332 wds:Q58862256-8E41F354-9FC1-4EF3-839D-E0DC3A5B9696 wds:Q58862256-95981754-33DD-41CD-BF88-8EF5EA7B2DF1 wds:Q58862256-9E9B42D2-03B1-4AA7-BFD9-63EB091CC635 wds:Q58862256-A155E1EA-84E9-4D28-9CBB-11D3AD7F2271 wds:Q58862256-B387B355-218B-4DF8-BDC3-0B37EBFDEB4B wds:Q58862256-CE73541E-1730-4D99-91D9-52383CFCAC06 wds:Q58862256-D148FB9D-21BD-4022-AC28-A029EDF1C586 wds:Q58862256-D47DCB71-7966-4E42-B3B8-CB4B5E92FEE9
cites work	AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia RNA interference targeting Fas protects mice from fulminant hepatitis Impairment of p53 acetylation, stability and function by an oncogenic transcription factor Histone deacetylases and cancer: causes and therapies Histone deacetylase inhibitors: from target to clinical trials Apoptosis: a link between cancer genetics and chemotherapy Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems Targeting death and decoy receptors of the tumour-necrosis factor superfamily Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation. The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest. Histone-deacetylase inhibitors: novel drugs for the treatment of cancer Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells Histone deacetylase inhibitors in cancer therapy: is transcription the primary target? Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling. Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers. Apo2L/TRAIL and its death and decoy receptors PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitors High-penetrance mouse model of acute promyelocytic leukemia with very low levels of PML-RARα expression
author name string	wds:Q58862256-0D0BDCB2-4EAE-431A-A689-FC03D168FCDC wds:Q58862256-0E4D7DFA-6083-4457-8DDD-3B55D23FE2C9 wds:Q58862256-11866FDC-2F07-42A4-A0B1-F3E39FFD08C4 wds:Q58862256-3779E996-23D1-484D-B6F0-50D87579F341 wds:Q58862256-5369D300-2928-4B68-8775-D857A5BB9AFE wds:Q58862256-54B9636B-2CF8-4881-BA03-C216B063BBDA wds:Q58862256-83474E4D-502E-4CA4-B9E1-02D9729E4344
author name string	Pier Giuseppe Pelicci Francesco Marchesi Alessandra Insinga Silvia Monestiroli Simona Ronzoni Andrea Viale Vania Gelmetti
rdfs:label	Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway (en) Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway (nl)
skos:prefLabel	Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway (en) Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway (nl)
name	Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway (en) Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway (nl)
author	wds:Q58862256-52E04234-88A9-48EF-A6BF-475DC7901794 wds:Q58862256-65DD3A01-61CB-45B9-A48A-B709735B8E56 wds:Q58862256-7F218F4B-7135-48C7-997E-EF70E8040584
author	Saverio Minucci Lucia Altucci Clara Nervi
title	wds:Q58862256-31441340-AD9A-4951-8A43-44568547CD1B
title	Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway (en)
page(s)	wds:Q58862256-5E88FAC5-699D-462E-A2D0-A28CCE5615D9
page(s)	71-76
instance of	wds:Q58862256-B5C7C04D-18C6-4BBD-821E-553207F2C8CD
instance of	scholarly article
main subject	wds:Q58862256-3DCBD437-7874-4100-8AE6-A7C42F313A6B
main subject	apoptotic process
PubMed ID	wds:Q58862256-B5FCF8C3-DD46-4C96-989C-EFB9FC7E3A9B
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15619634
PubMed ID	15619634
published in	wds:Q58862256-DB065AE6-731E-459D-AE5B-095313FFD0C9
published in	Nature Medicine
issue	wds:Q58862256-48593557-C80F-45CD-B17A-67BC4CB28DD3
volume	wds:Q58862256-6CBC83DE-F191-4F55-B7AF-FAAB77241DC9
issue	1
volume	11

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