About: Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation

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scientific article published on 01 August 2008

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2008 (uk) im August 2008 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'agostu de 2008 (ast) scientific article published on 01 August 2008 (en)
publication date	wds:Q58779353-3CC81274-34BB-4621-89B4-8C721888F399
publication date	2008-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q58779353-3137F254-44F8-44EC-9242-853D6DEDAC85
language of work or name	English
cites work	wds:Q58779353-026A4CE2-8921-4073-A1CB-1E54E70BC335 wds:Q58779353-049650A7-61DB-4BC6-AB58-18C85688E4E9 wds:Q58779353-116D1BC1-657F-48B0-A4B0-2E527DC879DC wds:Q58779353-247D84A0-14DA-43B6-80E9-6849F6F3B7E0 wds:Q58779353-24ED1277-681D-4EDA-9A45-07BAD46F9274 wds:Q58779353-30FF3EDB-8AFF-400C-B97B-8E651010726C wds:Q58779353-378F6F93-6341-43DA-A7BE-93AD2E745199 wds:Q58779353-37E613F0-703E-4835-935F-888028017CAC wds:Q58779353-3AE90BF1-AD5F-497A-A38A-1EA1ECDEC3F0 wds:Q58779353-409CC205-D31D-4418-B507-EAC1EA914EFA wds:Q58779353-46108312-69A3-4614-99EE-F9B6E70C62B7 wds:Q58779353-4A8A3E51-102A-4F41-889D-8855072E6D09 wds:Q58779353-4ABE666C-8314-47D6-BFF9-E5BB9CA56FBC wds:Q58779353-4E85DC40-5FBD-4571-A25F-351512FF23B0 wds:Q58779353-587E62E9-8780-4FD5-9056-12112D3F19B3 wds:Q58779353-5E1B2C03-75BE-470B-908E-503FDFD7397A wds:Q58779353-72F482A3-3A1E-4D82-8CE1-C8158EAE6710 wds:Q58779353-73F70DCC-E271-412A-844E-293DAE670294 wds:Q58779353-7AD75566-4B7D-4366-95C5-16CB76F9617B wds:Q58779353-7C634EE3-A5B9-45EF-922D-4E98A179898B wds:Q58779353-8CBF80A5-DC6B-4EF3-85BE-61B3630CDEE1 wds:Q58779353-92B46A92-F613-4284-BD23-36B34CF0C8D8 wds:Q58779353-9DECB1C1-606C-46DF-8279-9D2AA3F57C19 wds:Q58779353-9E248D9B-B13B-435D-9936-680C231BAC5C wds:Q58779353-A75F0AF2-199B-4E31-8BA4-FA8C987B2E9F wds:Q58779353-B0B5C7DB-CD06-41A2-B617-F85AC79D1082 wds:Q58779353-B5D56653-2662-4344-B4F6-E35F0113B990 wds:Q58779353-CD1E8F4E-D4C3-4772-9B3F-6B42F73BB87F wds:Q58779353-DA237BB1-7F1B-44F3-8ECB-6EF451E1A1D6 wds:Q58779353-E656EEFD-63D7-461D-98F8-0F9C0B8913D1 wds:Q58779353-E8586E21-FF1C-4935-8712-0147BC048154 wds:Q58779353-F5491806-5091-401C-B201-CBBAA912FB79 wds:Q58779353-FC9C8454-6FC7-4B24-8448-98B3D83217C1 wds:Q58779353-FFC1340D-143D-483F-98E9-37CC20260AD7
cites work	Dendritic cell (DC)-based protection against an intracellular pathogen is dependent upon DC-derived IL-12 and can be induced by molecularly defined antigens Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice Glycoconjugates in Leishmania infectivity Early parasite containment is decisive for resistance to Leishmania major infection. Natural killer cells in antiviral defense: function and regulation by innate cytokines Innate immune responses to infection The regulatory role of natural killer cells in multiple sclerosis. Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor. Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis. Live Leishmania promastigotes can directly activate primary human natural killer cells to produce interferon-gamma. Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells Human natural killer cell activating receptors. Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset Extracellular release of the glycosylphosphatidylinositol (GPI)-linked Leishmania surface metalloprotease, gp63, is independent of GPI phospholipolysis: implications for parasite virulence The macrophage-attachment glycoprotein gp63 is the predominant C3-acceptor site on Leishmania mexicana promastigotes A small region of the natural killer cell receptor, Siglec-7, is responsible for its preferred binding to alpha 2,8-disialyl and branched alpha 2,6-sialyl residues. A comparison with Siglec-9. Genomic and proteomic expression analysis of Leishmania promastigote and amastigote life stages: the Leishmania genome is constitutively expressed. Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice The paradox of matrix metalloproteinases in infectious disease Indications of the protective role of natural killer cells in human cutaneous leishmaniasis in an area of endemicity Cells from healthy non-exposed individuals produce cytokines to selected fractions of Leishmania promastigotes Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major Cytokine Gene Expression in Healing and Non-Healing Cases of Cutaneous Leishmaniasis in Response to In vitro Stimulation with Recombinant gp63 Using Semi-Quantitative RT-PCR NK cells in HIV infection: paradigm for protection or targets for ambush Targeted gene deletion of Leishmania major genes encoding developmental stage-specific leishmanolysin (GP63). Human natural killer cells: Molecular mechanisms controlling NK cell activation and tumor cell lysis Separation of leukocytes from blood and bone marrow. Introduction NK cell regulation of T cell-mediated responses. Involvement of a metalloprotease in spontaneous and phorbol ester-induced release of natural killer cell-associated Fc gamma RIII (CD16-II) NK cells, MHC class I molecules and the missing self Leishmania major: production of recombinant gp63, its antigenicity and immunogenicity in mice Vaccination of humans against cutaneous leishmaniasis: cellular and humoral immune responses Interleukin-2-activated natural killer cells may have a direct role in the control of Leishmania (Leishmania) amazonensis promastigote and macrophage infection Leishmania infection: surfaces and immunity.
author name string	wds:Q58779353-0C960127-6D5F-40BF-A1A8-B96DC36C8720 wds:Q58779353-40437C2C-05A3-4BC1-88F9-69C2F23EC184 wds:Q58779353-75861A0B-46D2-4CDE-99E9-D71740FDFDD5 wds:Q58779353-E6A5B060-1E01-4BB4-8B26-8A7D7E3F9F75
author name string	W R McMaster A Khamesipour A M Mohammadi T Lieke
rdfs:label	Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation (en) Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation (nl)
skos:prefLabel	Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation (en) Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation (nl)
name	Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation (en) Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation (nl)
author	wds:Q58779353-108CA7E5-6582-49C7-979D-6B823A92F966 wds:Q58779353-1D91A1E1-4E24-46A2-AA39-6CCF6E183D74 wds:Q58779353-593D934D-B68D-48C7-9443-E1DDEDC689EB wds:Q58779353-EB7483A7-87A9-4EFB-9C1D-CD8100341859
author	Susanne Nylén Hannah Akuffo Louise Berg Liv Eidsmo

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