About: mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in

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About: mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in Goto Sponge NotDistinct Permalink

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description	article (en) wetenschappelijk artikel (nl) наукова стаття, опублікована у вересні 2018 (uk) article scientifique publié en 2018 (fr) im März 2018 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q58776999-ACDC1638-1028-4A48-BB97-2585BE273081
publication date	2018-03-29 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q58776999-5188A272-1902-4B4A-A843-9C012695AD24
language of work or name	English
cites work	wds:Q58776999-161C14F8-08DE-4307-BDE2-313D46E18ACB wds:Q58776999-25DE0570-624D-4AB4-A46B-B4380A64BC13 wds:Q58776999-3921137E-EE30-44BB-8A6D-88B4CC2E6BD2 wds:Q58776999-46995BC4-A3C8-4B2F-9729-403D4B4EBE8B wds:Q58776999-4903DB90-2BC8-4D28-8085-0E9D9B818FF3 wds:Q58776999-5C90EE35-2F62-4A40-9976-3FF0BE05CE04 wds:Q58776999-6B549771-70A8-49AC-9893-B7BC756C62F3 wds:Q58776999-86BD29C2-B332-4D5A-AD78-4777C872179A wds:Q58776999-D8DB0EFB-24E2-479C-9E73-FFD496C8EE62 wds:Q58776999-DCC56815-84FD-4C76-82E7-A3A185A29A23 wds:Q58776999-DEA44672-0230-4F14-B639-245D5108EED8 wds:Q58776999-EA2CB8FB-9A80-46C9-928F-9271743B0E58 wds:Q58776999-EAB89653-C1D8-4E38-9CAC-D2936418EA41 wds:Q58776999-EDC620AB-EBA1-4BF1-9CC6-79CE7DB0A483 wds:Q58776999-F33A2561-515A-4B9C-ACE5-9660A4F01C31
cites work	Genome wide SNP array identified multiple mechanisms of genetic changes in Waldenstrom macroglobulinemia. MYD88 Mutations and Response to Ibrutinib in Waldenström's Macroglobulinemia Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding protein Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins Clinicopathological definition of Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia The cellular origin and malignant transformation of Waldenström macroglobulinemia. The genomic landscape of Waldenstrom macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis The WHIM-like CXCR4(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia. Phase I First-in-Human Study of Venetoclax in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma A new era for Waldenstrom macroglobulinemia: MYD88 L265P. MYD88 wild-type Waldenstrom Macroglobulinaemia: differential diagnosis, risk of histological transformation, and overall survival. Clonal architecture of CXCR4 WHIM-like mutations in Waldenström Macroglobulinaemia Transcriptome sequencing reveals a profile that corresponds to genomic variants in Waldenström macroglobulinemia. MYD88 (L265P) mutation is an independent risk factor for progression in patients with IgM monoclonal gammopathy of undetermined significance. Genome-wide repression of NF-κB target genes by transcription factor MIBP1 and its modulation by O-linked β-N-acetylglucosamine (O-GlcNAc) transferase
author name string	wds:Q58776999-1783C1D5-58EB-44FF-878C-22ACCBD56520 wds:Q58776999-2CCB2F8F-E4A9-443D-903F-AF4E46907A7F wds:Q58776999-2E111BB5-31D3-47F2-B379-39E17922BA37 wds:Q58776999-3A365322-3431-4417-949C-DD94D763D649 wds:Q58776999-3F69AB42-43A2-4F6B-B2E5-DCF03AA506DD wds:Q58776999-449B22E8-1343-46FE-90A2-8EF7A13FEC53 wds:Q58776999-49437638-80EA-487F-9F95-7E6B08D6883F wds:Q58776999-5028697F-1FFD-43B3-B274-0D7A6A1A6119 wds:Q58776999-5AE70824-AAAF-4272-BF7A-4A2DA915DFAF wds:Q58776999-74D5D564-235D-4CF2-990D-5FF5A5544D93 wds:Q58776999-768EE39B-E264-437E-8E4E-08A370CB3879 wds:Q58776999-7B9738FD-7353-41BF-AEC7-4633046C44F7 wds:Q58776999-83D5E147-6B7A-4B0F-B7BA-E040ACB3BF0F wds:Q58776999-9BB57E2B-E072-4B9B-A5FB-710C107FAF70 wds:Q58776999-D556DBA1-631D-4E1B-B6DA-D664B492FEA4 wds:Q58776999-D623D572-4CF1-499A-895E-C38C550C443A wds:Q58776999-E9531F73-8EFC-463C-AF19-E7D3DF24F9E6 wds:Q58776999-F00932EC-7C43-4979-807B-59FFACD28C59
author name string	Mario Cazzola Xia Liu Guang Yang Lian Xu Steven P Treon Jorge J Castillo Ruben D Carrasco Joshua Gustine Toni Dubeau Christopher J Patterson Robert J Manning Nickolas Tsakmaklis Amanda Kofides Manit Munshi Maria Luisa Guerrera Maria Demos Gloria G Chan Jiaji G Chen
rdfs:label	mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in (en) mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in (nl)
skos:prefLabel	mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in (en) mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in (nl)
name	mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in (en) mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in (nl)
author	wds:Q58776999-B7B9603B-1CFC-4263-9876-AFA209CF5AE1 wds:Q58776999-D5EF42D4-4F26-475B-8685-7C85A7565926 wds:Q58776999-DEFB9736-9AD4-4D38-A17D-92D991C3023B
author	Marzia Varettoni Luca Arcaini Zachary Hunter
title	wds:Q58776999-A81F7B67-23C1-4F3C-9E3C-11D7D43CDC10
title	MYD88 mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in CXCR4 (en)
page(s)	wds:Q58776999-1EB7DF8A-2342-477D-9E86-99335D286E9E
page(s)	e408-e411
instance of	wds:Q58776999-0D31664B-E271-4450-AD5A-FA56F7BFBC51
instance of	scholarly article
main subject	wds:Q58776999-45088000-0BA4-4556-B5D1-0724B6A959E9 wds:Q58776999-6412ACFB-B781-4FE4-B2F7-6BF200F882D4
main subject	hematology Waldenström macroglobulinemia
PubMed ID	wds:Q58776999-F160A950-0B4A-49D9-B2E5-7BB4ADF3B4AB
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/29599202

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