About: Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy

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About: Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy Goto Sponge NotDistinct Permalink

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scholarly article by Fan Yang et al published 24 September 2018 in Cell Death and Disease

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description	wetenschappelijk artikel (nl) наукова стаття, опублікована у вересні 2018 (uk) article scientifique publié en 2018 (fr) im September 2018 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Fan Yang et al published 24 September 2018 in Cell Death and Disease (en)
publication date	wds:Q58700479-AD88BABE-19C8-4BFE-B65E-95FEEA2FFF7B
publication date	2018-09-24 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q58700479-957BE88A-25D3-4102-9C88-97E64094DC8E
language of work or name	English
cites work	wds:Q58700479-09879CEA-68F8-4620-9B28-EB7B6F7ADC38 wds:Q58700479-0BE51619-165A-4959-B4DF-4631D4730544 wds:Q58700479-0CD0943B-2867-45D1-9E49-0FCF5CB0887A wds:Q58700479-23304D82-1A1F-44F2-B57B-AE8CDC897C7A wds:Q58700479-2CD46A36-029E-4555-9E29-E1CB0957CE80 wds:Q58700479-3DF11B02-ED26-44BD-9329-2137DCF5894F wds:Q58700479-472B344D-2B5A-4D19-9408-DE14A78588CB wds:Q58700479-5C2A4C05-A5EB-4E8B-B1D5-18680DD3A7D0 wds:Q58700479-66F3A5D1-7E0C-4C1B-A71D-C1EEC1A58248 wds:Q58700479-6DC81668-2636-4EB2-8613-3B3ABC7E5735 wds:Q58700479-712F5E41-DF58-475B-AD2B-7222484A7D0B wds:Q58700479-7385E98B-F39C-4CF4-B44F-3703EA866F18 wds:Q58700479-73AFD3E2-625A-45AD-8937-D8174ED49537 wds:Q58700479-75FB9073-13EB-4060-9360-86B06367AD1E wds:Q58700479-77A78496-EBE1-48B0-A828-61B6C6341487 wds:Q58700479-7E219312-BE39-4B4C-B967-17D69C6BD22D wds:Q58700479-84081C3B-FD3D-48D2-8D93-AF02D4089749 wds:Q58700479-845EDCDE-1BE2-4E64-91EA-35E6FBEA4C5A wds:Q58700479-88875A17-A47B-4AD6-872C-ECB189098C74 wds:Q58700479-906C03C2-9BBA-4886-AD36-32DF9604BAC2 wds:Q58700479-9B70B73B-E84C-4709-970E-DB87AC144191 wds:Q58700479-9FFD36D1-E964-4F0B-9701-03376A7A7D57 wds:Q58700479-A0545411-5D24-4A8E-A284-82CCCAE946A7 wds:Q58700479-A5354359-8D68-447B-8604-487A6C36664E wds:Q58700479-A858C080-2D6D-48AD-937E-C4191176C843 wds:Q58700479-A921ACBE-25A2-47BE-BEF1-016FE54511AB wds:Q58700479-AFFFDD6F-AB2C-479E-A948-077D838BF070 wds:Q58700479-B1E6F5E7-F60A-4E03-B90F-520746A9D6CF wds:Q58700479-BA4073FA-02D5-4297-8065-B5FEC341EAF6 wds:Q58700479-C4E17629-70E2-417A-BE40-A4339D18175C wds:Q58700479-CBFB9468-8CDF-424F-97C3-DC20501D3999 wds:Q58700479-E0877934-2A57-43F1-9CB2-C0AD71B6C4DF wds:Q58700479-EAF740A5-C3F0-4974-9F80-E0B7234E58BB wds:Q58700479-F272A3BD-DD92-4021-9BA1-8B1178424B1A
cites work	Modulation of fibroblast functions by interleukin 1: increased steady-state accumulation of type I procollagen messenger RNAs and stimulation of other functions but not chemotaxis by human recombinant interleukin 1 alpha and beta Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c Evolution and functions of long noncoding RNAs Genome regulation by long noncoding RNAs. Diabetic cardiomyopathy, causes and effects MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy Rosuvastatin alleviates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome and MAPK pathways in a type 2 diabetes rat model The NLRP3 inflammasome: a sensor for metabolic danger? Molecular mechanisms of long noncoding RNAs Pyroptosis: host cell death and inflammation Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. Long noncoding RNAs: functional surprises from the RNA world Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model Pirfenidone attenuates cardiac fibrosis in a mouse model of TAC-induced left ventricular remodeling by suppressing NLRP3 inflammasome formation. Microarray analysis of differentially expressed microRNAs in non-regressed and regressed bovine corpus luteum tissue; microRNA-378 may suppress luteal cell apoptosis by targeting the interferon gamma receptor 1 gene. GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death Inflammatory cytokines induce the transformation of human dermal microvascular endothelial cells into myofibroblasts: a potential role in skin fibrogenesis. The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling MicroRNA-9 inhibits hyperglycemia-induced pyroptosis in human ventricular cardiomyocytes by targeting ELAVL1. Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways Down-regulation of lncRNA KCNQ1OT1 protects against myocardial ischemia/reperfusion injury following acute myocardial infarction. Long Non-Coding RNA KCNQ1OT1 Promotes Cataractogenesis via miR-214 and Activation of the Caspase-1 Pathway Knockdown of long non-coding RNA KCNQ1OT1 depressed chemoresistance to paclitaxel in lung adenocarcinoma. The Role of the NLRP3 Inflammasome in Fibrosis KCNQ1OT1 promotes melanoma growth and metastasis. LncRNA KCNQ1OT1 ameliorates particle-induced osteolysis through inducing macrophage polarization by inhibiting miR-21a-5p. Downregulation of Long Non-Coding RNA Kcnq1ot1: An Important Mechanism of Arsenic Trioxide-Induced Long QT Syndrome. Differential methylation of lncRNA KCNQ1OT1 promoter polymorphism was associated with symptomatic cardiac long QT. Interleukin-1 increases fibronectin production by cultured rat cardiac fibroblasts Apigenin alleviates STZ-induced diabetic cardiomyopathy HMGB1 attenuates TGF-β-induced epithelial-mesenchymal transition of FaDu hypopharyngeal carcinoma cells through regulation of RAGE expression
author name string	wds:Q58700479-12CDCCE3-E68D-4877-B3FA-CF883D2324EC wds:Q58700479-5620640C-D015-4932-9785-0AC4DA2EEEDF wds:Q58700479-63FC445D-4D35-4C85-A948-1A2E6214082C wds:Q58700479-746C9C19-A845-47C6-BC71-87528E57A188 wds:Q58700479-76EDC745-9FBB-427D-B304-6FE9A4A531F9 wds:Q58700479-7E81E0BA-2762-432A-A256-57DA1B00B6AC wds:Q58700479-8E752521-1069-4343-A548-1FAC7320C517 wds:Q58700479-921731E2-A3DE-49FC-9B26-1ED4E3D27D67 wds:Q58700479-B64466F6-9B19-4E93-97BE-4F7573F1AF3E wds:Q58700479-CA8FF6B3-E8CB-497E-9971-FDDAE645CFE7 wds:Q58700479-DD83D365-26C9-4155-A0C7-D961FBFED2DC wds:Q58700479-EB026754-9DDF-48D3-974F-185CB332E416 wds:Q58700479-F04DFA72-7073-467D-88A9-164BDEE67AD0 wds:Q58700479-FBE0BA5F-C5E3-47C6-9A4D-3531BEAFD4A2
author name string	Yang Li Fan Yang Jie Lv Ying Qin Xi Chen Lihong Wang Xi Sun Yueqiu Wang

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