About: p38α suppresses normal and cancer cell proliferation by antagonizing the JNK

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About: p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway Goto Sponge NotDistinct Permalink

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article by Lijian Hui et al published 29 April 2007 in Nature Genetics

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована у квітні 2007 (uk) article scientifique publié en 2007 (fr) im April 2007 veröffentlichter wissenschaftlicher Artikel (de) article by Lijian Hui et al published 29 April 2007 in Nature Genetics (en)
publication date	wds:Q58326859-4BF2F939-58AC-4498-9EBC-017B118F1A91
publication date	2007-04-29 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q58326859-A620608F-7053-40CF-8ADD-5BC280916F91
language of work or name	English
exact match	wds:Q58326859-48C8ABA7-09BE-42D5-BACC-E25FBB8A7A4E
exact match	https://scigraph.springernature.com/pub.10.1038/ng2033
cites work	wds:Q58326859-00EE23C6-AE4A-464F-93F1-581A345F7AFA wds:Q58326859-0748A1AE-D49D-49DB-B665-49930A93DD5C wds:Q58326859-112C83E5-E1D5-4E5D-BC01-1CA23E770929 wds:Q58326859-1A377E27-8969-47C4-B083-1C321A5A1226 wds:Q58326859-1CE82B3A-2B73-4747-881B-933A0FC8B605 wds:Q58326859-27A215C4-9B61-4E48-823B-E6497D7A7BB7 wds:Q58326859-27B42A7C-1B3D-487B-B0B0-DCD3635C00AA wds:Q58326859-2ED52ADB-F263-41D1-8809-04D473EFD427 wds:Q58326859-2F55FAC0-EB82-49C8-B6EF-6B13A52D890D wds:Q58326859-2FCCA2BF-F569-4A7C-B4A5-CE8B4ECC45F6 wds:Q58326859-336A82BB-973D-4465-B330-5E31D33210E0 wds:Q58326859-34FA6D2B-41F5-42EE-8915-F3A8F32976CE wds:Q58326859-387DE5FB-92C6-4724-BA4A-85EC553FC4D1 wds:Q58326859-3A5BEA0F-6311-455C-8F05-97D1B67FEF59 wds:Q58326859-47E7B461-07E1-4994-8E69-BA4C5A62C834 wds:Q58326859-5C805F2D-AAC3-49C7-A112-CAA3766A358F wds:Q58326859-6495DD9D-1451-4DFD-8EF5-789A80287674 wds:Q58326859-679F58BF-D004-4CC8-A2BD-366021F822E2 wds:Q58326859-6CA0B2C0-F51E-4E0D-A9D6-30E6E97BA13E wds:Q58326859-77C90CE0-F6A6-4801-84DC-6B7CCDB88249 wds:Q58326859-78FA8BF4-D132-42FF-B784-E50DCB72CBCB wds:Q58326859-7CE332CA-1D83-4EC0-8A57-CCDF1ADBE637 wds:Q58326859-8B3B2CF5-9C54-4DF7-83EF-723CA54D981D wds:Q58326859-8D97C2B5-1945-4865-8684-E24B5E199BA3 wds:Q58326859-8DC43169-DD5C-4996-B21F-28CEE8E3CB53 wds:Q58326859-8F6E736A-CA0F-441B-AAA8-985970B0C998 wds:Q58326859-90F7A2E1-C7A1-48C8-887B-AF592105BA96 wds:Q58326859-975EFBFC-493A-4D87-A9E0-8ED83BF123C7 wds:Q58326859-AD212100-B911-4D18-BE8C-323D4E953300 wds:Q58326859-AE88F9EC-3284-4BA8-A72A-872C22C872AC wds:Q58326859-B1AE0685-84E8-4D87-B8DA-B7B72C8399EA wds:Q58326859-B84737E7-47A8-46E3-8B36-34B61FC02DA1 wds:Q58326859-BBA9012E-AE85-4278-92F7-49EDDA967F18 wds:Q58326859-C4A12C72-8276-4ADA-BCC1-D47600EEBD7D wds:Q58326859-C61FB946-DD1E-46F6-B800-6E6ACB141E85 wds:Q58326859-C9BE639C-0F33-4E1C-9C1A-0E4016518C3C wds:Q58326859-CE7E28C3-291C-4F61-BB61-F1D3B1ED1602 wds:Q58326859-DA61F57F-7195-4D7E-BEBF-9FCC0C147EBB wds:Q58326859-DD27E8DC-8DFE-48DC-A7A0-4C2C23D62DF4 wds:Q58326859-DDB28AB5-E556-460C-ACFC-4053FF35DAB6 wds:Q58326859-E4018315-FAA0-483D-8D93-EC0EE568F885 wds:Q58326859-FD7CEF21-118C-4449-B138-32F29690F7B3
cites work	Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis Mechanism of p38 MAP kinase activation in vivo. c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells. Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53 The challenges of translating knockout phenotypes into gene function Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation Control of cell cycle progression by c-Jun is p53 dependent c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway Leukemic transformation of normal murine erythroid progenitors: v- and c-ErbB act through signaling pathways activated by the EpoR and c-Kit in stress erythropoiesis IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence. Mammalian MAP kinase signalling cascades Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis PRAK is essential for ras-induced senescence and tumor suppression Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis p38 MAP kinase's emerging role as a tumor suppressor Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway. Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development Inducible gene targeting in mice Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2 Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation JNK2 is a positive regulator of the cJun transcription factor Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases Mouse ATF-2 null mutants display features of a severe type of meconium aspiration syndrome Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation c-Jun NH2-terminal kinase/c-Jun signaling promotes survival and metastasis of B lymphocytes transformed by Theileria Hepatocyte-specific expression of Cre recombinase Green fluorescent protein tagging of extracellular signal-regulated kinase and p38 pathways reveals novel dynamics of pathway activation during primary and metastatic growth Involvement of the p38 mitogen-activated protein kinase cascade in hepatocellular carcinoma
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