About: Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes

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About: Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes Goto Sponge NotDistinct Permalink

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scholarly article by Theresia Kraft published in April 2013

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована у квітні 2013 (uk) article scientifique publié en 2013 (fr) im April 2013 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Theresia Kraft published in April 2013 (en)
publication date	wds:Q58087516-EC288789-930B-4BE1-A214-C2D7B78D53F8
publication date	2013-04-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q58087516-03C45C23-4C07-46A6-9548-5F968D9E5DE1 wds:Q58087516-05FFF902-CBA2-47A7-95A1-FF4A01D1476D wds:Q58087516-07B8FDE6-61D0-4D2E-BE23-339C246712B4 wds:Q58087516-160F7DF0-CBAA-46B4-A53E-89ADEF358E1E wds:Q58087516-16238EE1-7399-440F-B4AB-D89268A9D943 wds:Q58087516-16A834C5-D7E8-4169-832D-193BA2DD14F4 wds:Q58087516-17311670-C831-4AD0-BAED-2D0A0DF319DF wds:Q58087516-18750B4C-5A99-4141-9F98-0A1B4D60B6F9 wds:Q58087516-2D9513CC-B864-4B82-B8E7-B75778EF9FF5 wds:Q58087516-40A85CD0-B53B-4667-A9E2-8CE03B9F89AD wds:Q58087516-575F9AD6-B6E0-4C04-98A5-A7D6AB2DAA60 wds:Q58087516-724E5730-9ECC-467A-819C-C5D516BA9B3D wds:Q58087516-7CFAAA39-BD20-4F9A-8B15-6A1BFFDEB2C2 wds:Q58087516-7D792C55-9F83-4A4F-86AC-FFD6400F31E0 wds:Q58087516-800D5F80-52E3-43E0-B280-9EC6F17C4956 wds:Q58087516-8887D8F3-E33D-4A36-A1D0-72F3E574AE8F wds:Q58087516-8AA181C7-927D-42F4-A405-E9027C428545 wds:Q58087516-909E0E5E-35C1-467E-ACE7-6D66A7140032 wds:Q58087516-A2561D63-9A2C-435F-A176-C9CADF272EC4 wds:Q58087516-AF299B71-D6AC-43BA-88A3-94AAA8725344 wds:Q58087516-B0A01117-4865-4C71-A06B-C2E83144D53F wds:Q58087516-B11A7F77-5F8F-46C3-B1B6-113AA4E8C2F1 wds:Q58087516-C73AB650-CB7B-4717-84C2-7FD64FBA3A99 wds:Q58087516-CC432E55-8622-42AE-BE72-63114335B1E7 wds:Q58087516-CF6820A0-E1FE-417E-A179-7C73EC89EF51 wds:Q58087516-D10128C1-7656-4BEB-873C-6E9DF492F6CB wds:Q58087516-DCB9208F-7633-40BC-BA08-0A61CC4F3D82 wds:Q58087516-E4ADBAC5-67DB-4A00-89C8-FB5A08E2DEFE wds:Q58087516-ED2FA2F8-2EB9-4CCC-A6EE-0C4FDE1601B6 wds:Q58087516-F8B558E8-F30D-4E06-B7CC-9B16D37E86D5 wds:Q58087516-FE50C4C1-A836-4CE3-AE95-44777521D0BE wds:Q58087516-FFA8B6EF-5A60-4ECC-AA21-4244100B38A3
cites work	Cardiomyopathy mutations reveal variable region of myosin converter as major element of cross-bridge compliance. Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments. The familial hypertrophic cardiomyopathy-associated myosin mutation R403Q accelerates tension generation and relaxation of human cardiac myofibrils Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure American College of Cardiology/European Society of Cardiology Clinical Expert Consensus Document on Hypertrophic Cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the Europ Effect of Ca2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implications for regulation of muscle contraction Rate of force generation in muscle: correlation with actomyosin ATPase activity in solution Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function Protein kinase A phosphorylates titin's cardiac-specific N2B domain and reduces passive tension in rat cardiac myocytes Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium. Myocardial Structure and Function Differ in Systolic and Diastolic Heart Failure Skeletal muscle expression and abnormal function of beta-myosin in hypertrophic cardiomyopathy Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary Artery Risk Development in (Young) Adults Unequal allelic expression of wild-type and mutated β-myosin in familial hypertrophic cardiomyopathy. Effects of calcium, inorganic phosphate, and pH on isometric force in single skinned cardiomyocytes from donor and failing human hearts Molecular diversity of myofibrillar proteins: gene regulation and functional significance Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy The effect of myosin light chain 2 dephosphorylation on Ca2+ -sensitivity of force is enhanced in failing human hearts Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy The in vitro motility activity of beta-cardiac myosin depends on the nature of the beta-myosin heavy chain gene mutation in hypertrophic cardiomyopathy Troponin I phosphorylation in the normal and failing adult human heart Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease. Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies Increased Ca2+-sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins Point mutations in human beta cardiac myosin heavy chain have differential effects on sarcomeric structure and assembly: an ATP binding site change disrupts both thick and thin filaments, whereas hypertrophic cardiomyopathy mutations display normal Microarchitecture is severely compromised but motor protein function is preserved in dystrophic mdx skeletal muscle The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy Mutation of the myosin converter domain alters cross-bridge elasticity Hypertrophic cardiomyopathy-related beta-myosin mutations cause highly variable calcium sensitivity with functional imbalances among individual muscle cells Malignant hypertrophic cardiomyopathy caused by the Arg723Gly mutation in beta-myosin heavy chain gene Quantification of mutant versus wild-type myosin in human muscle biopsies using nano-LC/ESI-MS
author name string	wds:Q58087516-00F34015-5BAF-4F88-9FD3-0BDF0F96A0EB wds:Q58087516-0DBEFE1B-2230-42FB-BCD7-92FAC08D8CE5 wds:Q58087516-425C99FE-6938-4A90-9D11-F68A00FBA50F wds:Q58087516-4A130D7B-524F-429F-A8A4-6F21013DE62F wds:Q58087516-91287225-4089-49BB-A541-3EEAEEF18716 wds:Q58087516-964AF8FC-1440-4C34-B07C-DC54B0689569
author name string	Bernhard Brenner Almuth Brandis Antonio Francino Snigdha Tripathi Francisco Navarro-Lopez Julie L. Hodgkinson
rdfs:label	Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes (en) Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes (nl)
skos:prefLabel	Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes (en) Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes (nl)
name	Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes (en) Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes (nl)
author	wds:Q58087516-25645319-5908-415A-9506-ACE33931E9C4 wds:Q58087516-25B29F13-A3F8-4775-B2C4-4E2BE455B094 wds:Q58087516-32D8752B-D6AD-46A8-BB30-1F25672E1325 wds:Q58087516-4B17A0A9-596A-4C0B-AED2-5ED2090D242D wds:Q58087516-C2655719-745F-44D2-ABFF-CB48DB086C54 wds:Q58087516-F0AEEE79-DB85-40C9-8008-55216F09FAEC
author	Jolanda van der Velden E. Rosalie Witjas-Paalberends Ger Stienen Nicky M. Boontje

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