About: Follicle-Stimulating Hormone (FSH) Stimulates Phosphorylation and Activation of Protein Kinase B (PKB/Akt) and Serum and Glucocorticoid-Induced Kinase (Sgk): Evidence for A Kinase-Independent Signaling by FSH in Granulosa Cells

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About: Follicle-Stimulating Hormone (FSH) Stimulates Phosphorylation and Activation of Protein Kinase B (PKB/Akt) and Serum and Glucocorticoid-Induced Kinase (Sgk): Evidence for A Kinase-Independent Signaling by FSH in Granulosa Cells Goto Sponge NotDistinct Permalink

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rdf:type	Item
description	article (en) wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2000 (uk) im August 2000 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q58055435-73D59F73-A0E8-4C58-B96A-F02E223C4AEF
publication date	2000-08-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q58055435-2880FEFA-DBF5-469F-808E-BF3486775F8B wds:Q58055435-5FA1A32E-36B7-4A37-989E-31C2479622A6 wds:Q58055435-73D77D5D-4FA7-4F0B-B60A-115312C52090 wds:Q58055435-97A3B251-8849-4EC9-BC3D-FC6CF178E3FD
author name string	JoAnne S. Richards Allison E. Falender Gary L. Firestone Ignacio J. Gonzalez-Robayna
rdfs:label	Follicle-Stimulating Hormone (FSH) Stimulates Phosphorylation and Activation of Protein Kinase B (PKB/Akt) and Serum and Glucocorticoid-Induced Kinase (Sgk): Evidence for A Kinase-Independent Signaling by FSH in Granulosa Cells (en) Follicle-Stimulating Hormone (nl)
skos:prefLabel	Follicle-Stimulating Hormone (FSH) Stimulates Phosphorylation and Activation of Protein Kinase B (PKB/Akt) and Serum and Glucocorticoid-Induced Kinase (Sgk): Evidence for A Kinase-Independent Signaling by FSH in Granulosa Cells (en) Follicle-Stimulating Hormone (nl)
name	Follicle-Stimulating Hormone (FSH) Stimulates Phosphorylation and Activation of Protein Kinase B (PKB/Akt) and Serum and Glucocorticoid-Induced Kinase (Sgk): Evidence for A Kinase-Independent Signaling by FSH in Granulosa Cells (en) Follicle-Stimulating Hormone (nl)
author	wds:Q58055435-06404B0F-552C-4FD6-BF16-54ED515CB273
author	Scott Ochsner
title	wds:Q58055435-53830B81-1CAD-4992-95A9-1B1F82BA9799
title	Follicle-Stimulating Hormone (FSH) Stimulates Phosphorylation and Activation of Protein Kinase B (PKB/Akt) and Serum and Glucocorticoid-Induced Kinase (Sgk): Evidence for A Kinase-Independent Signaling by FSH in Granulosa Cells (en)
page(s)	wds:Q58055435-F1DA82C8-2651-46E0-9704-D9B86FCFB50E
page(s)	1283-1300
instance of	wds:Q58055435-82FABB07-636A-48D6-9E69-C458786B49E6
instance of	scholarly article
main subject	wds:Q58055435-C23BD324-7709-4E9E-8C27-45C0D08B9F0D
main subject	phosphorylation
PubMed ID	wds:Q58055435-E2555F94-8EFF-4D6D-9D8E-4E07E77DDE3A
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10935551
PubMed ID	10935551
published in	wds:Q58055435-513EE192-614A-454E-814C-3B8B83221AE4
published in	Molecular Endocrinology
issue	wds:Q58055435-8023EE12-D339-41EE-9E89-268A0398A006
volume	wds:Q58055435-C00CCF5F-4243-4861-8A47-90757B7070D8
issue	8
volume	14
DOI	wds:Q58055435-77ACAF51-21A8-4DA8-9551-2DFB162FE77D
DOI	http://dx.doi.org/10.1210/MEND.14.8.0500
DOI	10.1210/MEND.14.8.0500
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q58055435
is cites work of	APPL1, APPL2, Akt2 and FOXO1a interact with FSHR in a potential signaling complex Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression. Minireview: physiological and pathological actions of RAS in the ovary Involvement of Sp1 and SREBP-1a in transcriptional activation of the LDL receptor gene by insulin and LH in cultured porcine granulosa-luteal cells Involvement of FoxO1 in the effects of follicle-stimulating hormone on inhibition of apoptosis in mouse granulosa cells FSH and FOXO1 regulate genes in the sterol/steroid and lipid biosynthetic pathways in granulosa cells Beta-catenin (CTNNB1) promotes preovulatory follicular development but represses LH-mediated ovulation and luteinization Targeted disruption of Pten in ovarian granulosa cells enhances ovulation and extends the life span of luteal cells Phosphoinositide 3-kinase p110δ mediates estrogen- and FSH-stimulated ovarian follicle growth The ovary: basic biology and clinical implications FSH signaling pathways in immature granulosa cells that regulate target gene expression: branching out from protein kinase A. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation Molecular mechanisms of ovulation: co-ordination through the cumulus complex Role of the phosphatidylinositol-3-kinase and extracellular regulated kinase pathways in the induction of hypoxia-inducible factor (HIF)-1 activity and the HIF-1 target vascular endothelial growth factor in ovarian granulosa cells in response to fol Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells Epac: effectors and biological functions Genetic changes in nonepithelial ovarian cancer Regulation of steroidogenic genes by insulin-like growth factor-1 and follicle-stimulating hormone: differential responses of cytochrome P450 side-chain cleavage, steroidogenic acute regulatory protein, and 3beta-hydroxysteroid dehydrogenase/isomera Search for new cyclic AMP-binding proteins. Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase The ERK-dependent signalling is stage-specifically modulated by FSH, during primary Sertoli cell maturation. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Emerging roles for the FSH receptor adapter protein APPL1 and overlap of a putative 14-3-3τ interaction domain with a canonical G-protein interaction site Multiple facets of follicle-stimulating hormone receptor function. Mapping the follicle-stimulating hormone-induced signaling networks The mammalian ovary from genesis to revelation FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development. Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis Identification and functional analysis of novel phosphorylation sites in Cx43 in rat primary granulosa cells Chorionic gonadotropin regulates prostaglandin E synthase via a phosphatidylinositol 3-kinase-extracellular regulatory kinase pathway in a human endometrial epithelial cell line: implications for endometrial responses for embryo implantation Induction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from Smad Comparison of assisted reproductive technology outcomes in infertile women with polycystic ovary syndrome: In vitro maturation, GnRH agonist, and GnRH antagonist cycles Role of the intracellular domains of the human FSH receptor in G(alphaS) protein coupling and receptor expression Hormonal control of Sertoli cell metabolism regulates spermatogenesis Promotion of EGF receptor signaling improves the quality of low developmental competence oocytes. Constitutively active protein kinase A qualitatively mimics the effects of follicle-stimulating hormone on granulosa cell differentiation. Impact of Carbohydrate Heterogeneity in Function of Follicle-Stimulating Hormone: Studies Derived from in Vitro and in Vivo Models1 E-cadherin-mediated cell contact prevents apoptosis of spontaneously immortalized granulosa cells by regulating Akt kinase activity Regulation of Akt expression and phosphorylation by 17beta-estradiol in the rat uterus during estrous cycle NH2 terminus of PTB-associated splicing factor binds to the porcine P450scc IGF-I response element Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation Activation of PKA, p38 MAPK and ERK1/2 by gonadotropins in cumulus cells is critical for induction of EGF-like factor and TACE/ADAM17 gene expression during in vitro maturation of porcine COCs Increased Urinary Phthalate Levels in Women with Uterine Leiomyoma: A Case-Control Study Dominant negative effects of human follicle-stimulating hormone receptor expression-deficient mutants on wild-type receptor cell surface expression. Rescue of oligomerization-dependent defective receptor expression by using cognate decoys Inhibition of phosphatase and tensin homologue (PTEN) in human ovary in vitro results in increased activation of primordial follicles but compromises development of growing follicles Fragile X premutation RNA is sufficient to cause primary ovarian insufficiency in mice Human follicle-stimulating hormone (FSH) receptor interacts with the adaptor protein APPL1 in HEK 293 cells: potential involvement of the PI3K pathway in FSH signaling Integrating microRNAs into the complexity of gonadotropin signaling networks The adapter protein APPL1 links FSH receptor to inositol 1,4,5-trisphosphate production and is implicated in intracellular Ca(2+) mobilization SGK1-sensitive renal tubular glucose reabsorption in diabetes. Valproate-induced alterations in human theca cell gene expression: clues to the association between valproate use and metabolic side effects Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB. Decreased intestinal glucose transport in the sgk3-knockout mouse Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP-PNP

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