About: In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors

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About: In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors Goto Sponge NotDistinct Permalink

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 2007 (uk) article scientifique publié en 2007 (fr) im März 2007 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q58001173-8B7B1524-BC55-4163-88E0-716264D13B6B
publication date	2007-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q58001173-1E4E2AB6-A5D1-4359-B41E-6206FF268272
language of work or name	English
cites work	wds:Q58001173-62652571-D754-4134-829B-E767DD1BF325
cites work	Mutations of the BRAF gene in human cancer
author name string	wds:Q58001173-0827BDC6-B94B-450D-865E-EDF2ACAFC0C1 wds:Q58001173-2302E1A2-8A7F-4AAC-B7CE-833314CB9068 wds:Q58001173-3DECF52C-BED5-44D4-AB37-52B0383D7EED wds:Q58001173-62F68823-6DAF-4E7B-A825-28F0400DF355 wds:Q58001173-6A7706AC-B0E9-4DFD-9AB8-6B8AA1BCCD56 wds:Q58001173-6AB45FB0-F8A3-4474-AE27-1E5D3EC31B6C wds:Q58001173-7AFE8A24-2AB9-4645-A2EC-64AF4BB7F654 wds:Q58001173-A2647533-76A1-4FE3-B0CD-0415B82A6ABB wds:Q58001173-C6A1DAC4-525A-4629-9C70-BD5E5A08F97C wds:Q58001173-C761D518-EB54-4387-B1A7-8E8043E3E7AC wds:Q58001173-D3960778-0F17-4C8C-B664-E760596FEAC7 wds:Q58001173-DC5A52BF-1C71-470F-9EEE-AE967D80EA49 wds:Q58001173-E32B838A-3B5C-4CE2-99CE-392672C44E1F wds:Q58001173-EF485413-D9ED-477E-89F3-CB08A5CE05BC
author name string	Edward McDonald Gary Box Angela Hayes Alison Maloney Martin Rowlands Lisa Patterson Sharon Sanderson Karen Ball Sue Eccles Marissa Powers Paul A. Clarke S. Mark Roe Swee Y. Sharp Thomas P. Matthews
rdfs:label	In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors (en) In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors (nl)
skos:prefLabel	In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors (en) In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors (nl)
name	In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors (en) In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors (nl)
author	wds:Q58001173-2E935AEE-9782-457E-9355-D81F42F57644 wds:Q58001173-4047F044-9C7C-4E8C-A769-08A10C8FC2CA wds:Q58001173-5FC87495-B07B-4CA7-9591-5C33C84874FF wds:Q58001173-970A5F1D-3931-49F3-81FA-4EB329B514D5 wds:Q58001173-A44C4AC2-EF2F-4AD0-B3B5-F8237B1D0805 wds:Q58001173-A51ACEBC-0275-4CF4-A03B-71BC6F5D54BE wds:Q58001173-DFEA1E2B-1B3B-4190-8D9B-3F8077DCFDBC wds:Q58001173-F4C50861-56F8-4842-8062-7874BFD4971F
author	Paul Workman Richard Marais Laurence Pearl Wynne Aherne Chrisostomos Prodromou Florence Raynaud Kwai-Ming J. Cheung Kathy Boxall
title	wds:Q58001173-1E8A662C-174D-494D-862B-713BBB6FDEF9
title	In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors (en)
page(s)	wds:Q58001173-8F2AFDA9-62C7-496A-99EC-0833EACAC547
page(s)	2206-2216
instance of	wds:Q58001173-F1B2F8A7-F6BE-4337-97F3-78938869C850
instance of	scholarly article
main subject	wds:Q58001173-1175B345-CB39-4383-94CE-38CD59729F9F wds:Q58001173-1F04798A-A43E-4EEE-AAE9-F6A8C787E63C
main subject	wd:Q27096815 cancer research
PubMed ID	wds:Q58001173-81803B00-A485-4CF4-8597-9CFF71068902
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17332351
PubMed ID	17332351
published in	wds:Q58001173-4735EA42-6C57-44ED-AFAB-E24C654A932A
published in	Cancer Research
issue	wds:Q58001173-7FC48F56-1F00-4554-B5B1-D26864B549BF
volume	wds:Q58001173-89475EA0-C621-4A87-BCA7-64D3B000FCFA
issue	5
volume	67
DOI	wds:Q58001173-72C2C826-A4CA-4B28-8D07-63ECF287693B
DOI	http://dx.doi.org/10.1158/0008-5472.CAN-06-3473
DOI	10.1158/0008-5472.CAN-06-3473
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q58001173
is cites work of	A Phase II trial of 17-allylamino, 17-demethoxygeldanamycin (17-AAG, tanespimycin) in patients with metastatic melanoma. Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1 Probing the probes: fitness factors for small molecule tools The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90β Acquired resistance to 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin) in glioblastoma cells Inhibitors of the heat shock response: biology and pharmacology New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential. Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxel Thermodynamics of aryl-dihydroxyphenyl-thiadiazole binding to human Hsp90 Different Poses for Ligand and Chaperone in Inhibitor-Bound Hsp90 and GRP94: Implications for Paralog-Specific Drug Design Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside? Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX. Design and synthesis of pyrazole/isoxazole linked arylcinnamides as tubulin polymerization inhibitors and potential antiproliferative agents A cell-based screen for inhibitors of protein folding and degradation Proteome alteration induced by hTERT transfection of human fibroblast cells

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