About: Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2

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About: Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2 Goto Sponge NotDistinct Permalink

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scientific article published in Journal of Biological Chemistry

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rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 1997 (uk) article publié dans la revue scientifique Journal of Biological Chemistry (fr) im August 1997 veröffentlichter wissenschaftlicher Artikel (de) scientific article published in Journal of Biological Chemistry (en)
publication date	wds:Q57754194-5627D2A8-A970-4311-BE86-AC7212D02065
publication date	1997-08-29 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57754194-F5E55EF3-C85E-45A5-88B2-F8946551EDC4
language of work or name	English
cites work	wds:Q57754194-0645FCB3-9B95-48BB-B081-48CC6BA16C41 wds:Q57754194-17397F71-E3EB-44F1-8A3A-8E63B98CE19E wds:Q57754194-1BFFB224-180E-426B-B45D-EF554842E3FE wds:Q57754194-1CF4A20A-9AB2-4C00-B5E5-EEB6C25465FD wds:Q57754194-21849682-8F1C-4E86-906E-33A8CDD0825A wds:Q57754194-219E30F8-236F-46B9-BFCC-CCEE77CAFE8C wds:Q57754194-227088C8-098A-4CE4-8AFF-694E160284E3 wds:Q57754194-286AB31E-1706-422E-B7D4-5F8ADFFD59EF wds:Q57754194-42AEE3BC-8851-4FBC-84FF-4E646B0F8E0E wds:Q57754194-495C8242-E4A8-4E84-9B1B-8D45191C41FB wds:Q57754194-4BC1DC6A-8396-48BA-941C-DF676674B953 wds:Q57754194-55218DB0-08F9-4777-BAD3-CEFEA5E95374 wds:Q57754194-6112875C-8782-4CA2-B668-890CDFB95367 wds:Q57754194-67215B82-8851-49AB-9D4A-88ADE83F0D9E wds:Q57754194-6D72311C-19A2-4E77-AF51-6CB29203A627 wds:Q57754194-6D8E5A13-ABD5-4BB8-9882-A5E532818415 wds:Q57754194-6E3AA7DC-71FB-42A2-AF4C-153819CA8E11 wds:Q57754194-6E450131-55AA-4110-B927-328D937B4F60 wds:Q57754194-7BB5E611-2022-4ADA-A201-FFE2CC51F72A wds:Q57754194-8751ECC2-EC25-4272-8D06-BF148FECE5A6 wds:Q57754194-99AD7C00-0A0E-41AC-B371-ED547378B759 wds:Q57754194-A5B509DC-5A06-4315-8C96-06E9D589A812 wds:Q57754194-B508F223-3454-4EE0-86DC-C0DFABF87B9D wds:Q57754194-C7A8D9E6-015A-49B4-8D3C-F431C261AB98 wds:Q57754194-EE7CF8A1-E050-434F-8E2B-B4EBAFF4A466 wds:Q57754194-F1EF9914-47D5-41A3-91B1-B1BADDB389FB wds:Q57754194-F2BE4FCF-922F-441B-97E0-DA24430D08E1 wds:Q57754194-FDE2DE10-25A8-4C5A-9E37-8C07D15A5826 wds:Q57754194-FFC0FD86-39B7-4966-B4A9-096F208ED9A1
cites work	Identification of a ten-amino acid proline-rich SH3 binding site Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1 Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells The SH3 domain of Crk binds specifically to a conserved proline-rich motif in Eps15 and Eps15R Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation Binding of Transforming Protein, P47 gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins Two species of human CRK cDNA encode proteins with distinct biological activities pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk A ras-related gene with transformation suppressor activity Emerging components of the Crk oncogene product: the first identified adaptor protein Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. SH2 and SH3 domains Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites The Grb2 adaptor CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1 Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors A novel viral oncogene with structural similarity to phospholipase C Signalling through SH2 and SH3 domains DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1. Kinetic properties of Ash/Grb2-interacting GDP/GTP exchange protein.
author name string	wds:Q57754194-0A3C155B-04DA-4CBE-B577-54927E0BCD39 wds:Q57754194-11CF612C-32EF-4F48-B381-212722E6AD1B wds:Q57754194-1E19FB17-E794-42DC-9860-9C826A0EC9DA wds:Q57754194-45368A56-A31F-44F3-A0C9-9ABA21916BA8 wds:Q57754194-56EB27AD-CB10-4D6C-B7C6-7080669577BC wds:Q57754194-65FDB4F4-93C0-4EE7-A216-F85EEFA14D14 wds:Q57754194-9DFF6CDC-D767-4DBD-83E4-CB5C11B6B459 wds:Q57754194-A1BF928A-BC1C-40BD-9936-587D7A780FA7 wds:Q57754194-A4B30573-4CAF-4A4F-B318-E73CFDF48FC7 wds:Q57754194-A68029CE-E400-4195-981E-1B12EFE7ED3C wds:Q57754194-C2605E9F-63DE-4B1E-82AB-8181F8061815 wds:Q57754194-CA778B59-DBC6-470A-904D-2429AEAE3879 wds:Q57754194-DFE4EDA9-5E69-4F28-931D-A47A2B5F3880 wds:Q57754194-E0BE149D-824B-4699-A28D-6B7B62D39AFD wds:Q57754194-EC5BCBFB-130A-4BEE-973B-815C8B78AF24 wds:Q57754194-FBD7C934-DFC0-446A-A4F7-D04270FBDE7B
author name string	Michiyuki Matsuda M Matsuda John Groffen S Nagata J Groffen T Kurata Takeshi Kurata Osamu Sakai O Sakai Seisuke Hattori S Hattori Satoshi Nagata Y Kuraishi T Ichiba Yasunobu Kuraishi

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