About: A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis

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article by T. Lenglet et al published 21 January 2014 in European Journal of Neurology

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в січні 2014 (uk) article scientifique publié en 2014 (fr) im Januar 2014 veröffentlichter wissenschaftlicher Artikel (de) article by T. Lenglet et al published 21 January 2014 in European Journal of Neurology (en)
publication date	wds:Q57666978-9B0A7B98-7790-47F4-A730-3355A3656FFB
publication date	2014-01-21 00:00:00Z (xsd:dateTime)
cites work	wds:Q57666978-11FCB8BF-AFBB-45B7-9F34-6855403475D7 wds:Q57666978-13AD4281-F4B8-48E6-B766-F6DC0F4A809E wds:Q57666978-2B0D5C37-9961-4956-84E3-9EEE6AEB895F wds:Q57666978-44103120-03DD-4853-8777-BD286A5B749A wds:Q57666978-448282A2-2610-4418-A12C-80B89E4E2724 wds:Q57666978-4B5D0D34-0C53-4B93-BB0C-B65171C3BDD1 wds:Q57666978-5285AFFE-9EC3-4677-9625-236D87AC61FA wds:Q57666978-52E7837C-F072-4ADB-BC51-4738DAC7DC61 wds:Q57666978-54B441C4-D21C-433E-9F65-99043835051C wds:Q57666978-6CDCB526-127D-4686-A4AF-E3887821AABE wds:Q57666978-7058FB8E-D3D4-4050-9CB3-CCF818E92A61 wds:Q57666978-92677236-3CBA-4C91-9DC1-695B18FF879F wds:Q57666978-9CD6C35B-619C-4BB6-A4CE-1E27A6F74AFA wds:Q57666978-A0094B81-A67A-49F2-A901-B54549CB617D wds:Q57666978-A66271D1-BD4C-41E7-B003-1ECE63A49345 wds:Q57666978-B0C6E862-A8FC-49D9-B553-454AB4CCA7FD wds:Q57666978-BD9AA2EB-23C5-420A-8A70-5FC7F11A5CCF wds:Q57666978-C58FB222-D2E6-4745-A0B9-5E2A1776894F wds:Q57666978-D16635A0-62F8-4B35-A389-CFD81F315D81 wds:Q57666978-DC3E2A55-083B-4CAB-9384-FA47696BE304 wds:Q57666978-F958CB8B-1064-48A7-A27D-ADFA581653CD wds:Q57666978-FBD014BF-5DF5-45E8-A146-6B96D1CA0E3A
cites work	The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III). A clinical trial of creatine in ALS. How can we improve clinical trials in amyotrophic lateral sclerosis? Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial. Pentoxifylline in ALS: a double-blind, randomized, multicenter, placebo-controlled trial. Design, power, and interpretation of studies in the standard murine model of ALS El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis Efficacy and safety of xaliproden in amyotrophic lateral sclerosis: results of two phase III trials Review: The role of mitochondria in the pathogenesis of amyotrophic lateral sclerosis. Olesoxime (cholest-4-en-3-one, oxime): analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS. Preclinical and subclinical events in motor neuron disease Emerging targets and treatments in amyotrophic lateral sclerosis Characterization of oxaliplatin-induced chronic painful peripheral neuropathy in the rat and comparison with the neuropathy induced by paclitaxel ALS drug development: reflections from the past and a way forward Apoptosis in amyotrophic lateral sclerosis--what is the evidence? Dexpramipexole versus placebo for patients with amyotrophic lateral sclerosis (EMPOWER): a randomised, double-blind, phase 3 trial Olesoxime prevents microtubule-targeting drug neurotoxicity: selective preservation of EB comets in differentiated neuronal cells. The natural history of ALS is changing: improved survival
author name string	wds:Q57666978-4036847C-05B6-4950-8AAE-037617A66A49 wds:Q57666978-48A49CD6-F096-4E64-B4AE-99083D68EB8E wds:Q57666978-61040B4A-B36B-4AED-91F4-32D2EFC60595 wds:Q57666978-6D732F09-7C85-4488-8856-308C90045227 wds:Q57666978-78BB44D4-D766-47F4-9DC1-871603F395DF wds:Q57666978-8F3CB641-D738-4EC6-9D1D-C0824DA4E7CA wds:Q57666978-95801EE9-0ECB-4906-96B0-D6476EB59CB4 wds:Q57666978-96511054-6CD9-4DB9-914B-9C0E3984420A wds:Q57666978-A1E401C9-3691-46E2-AA17-884852CB4193 wds:Q57666978-BB254A78-CCE5-4584-84ED-61780269B98C
author name string	P. J. Shaw R. M. Pruss A. Ludolph J. L. Abitbol J. S. Mora L. Lacomblez T. Lenglet V. Cuvier V. Meininger W. Robberecht
rdfs:label	A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis (en) A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis (nl)
skos:prefLabel	A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis (en) A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis (nl)
name	A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis (en) A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis (nl)
title	wds:Q57666978-AE96CAEB-69FE-405D-8C12-D94EA2498028
title	A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis (en)
page(s)	wds:Q57666978-A616EBCC-F6CF-4855-A9FC-A8C41920DBE9
page(s)	529-536
instance of	wds:Q57666978-BD2FBD08-6E4F-402F-B05C-F93086645F08
instance of	scholarly article
main subject	wds:Q57666978-1853953A-84C7-478C-BD66-5D461D44EB7F wds:Q57666978-90AD86BF-1822-44D7-B49A-FF19ED4F0FF4
main subject	amyotrophic lateral sclerosis phase II clinical trial
PubMed ID	wds:Q57666978-BA7564B8-9B94-4095-8DF7-EB3B0F0E2B29
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24447620
PubMed ID	24447620
published in	wds:Q57666978-860E81C4-BE4F-4623-B27A-A55EC331C360
published in	European Journal of Neurology
issue	wds:Q57666978-7E660AD1-D03E-40C9-860E-D2D7A2AE5E94
volume	wds:Q57666978-551B57D7-EA03-4E87-A91F-69CAD9F71756
issue	3
volume	21
DOI	wds:Q57666978-BBDE966E-12CA-473A-9A3D-FA104BB08522
DOI	http://dx.doi.org/10.1111/ENE.12344
DOI	10.1111/ENE.12344

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