About: Clinical course of bladder neoplasms and single nucleotide polymorphisms in theCDKN2Agene

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article by Shigeru Sakano et al published 16 December 2002 in International Journal of Cancer

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 2002 (uk) im Dezember 2002 veröffentlichter wissenschaftlicher Artikel (de) article scientifique publié en décembre 2002 (fr) article by Shigeru Sakano et al published 16 December 2002 in International Journal of Cancer (en)
publication date	wds:Q57664903-0620FE59-22F8-49E8-BE13-01D21F7D70BD
publication date	2002-12-16 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57664903-3B9ED35E-B6BE-42CC-A92C-F60113C252D7
language of work or name	English
cites work	wds:Q57664903-07EE0F3F-2E57-4834-B1A2-273089B26324 wds:Q57664903-084CF4FD-F118-419B-A527-C986D0FB23DE wds:Q57664903-086FDA16-2DC1-4CA5-9AB7-B62A750514A8 wds:Q57664903-15DD13CB-E644-429C-B130-E02F1D5A7BCC wds:Q57664903-1A2CB51D-6F4F-41C6-B4D4-5F21CD767F73 wds:Q57664903-1C1F7903-7E88-4EBB-BDCF-1D2A995B88F0 wds:Q57664903-3416013B-C4F5-4ED7-A49B-695151D04CED wds:Q57664903-3E880A09-9DF5-4CCB-B772-1616F5C19FE1 wds:Q57664903-49943A91-DE21-4B1A-B0C6-15F553888859 wds:Q57664903-5D553E4F-F636-43E4-8A06-F1E2A476D006 wds:Q57664903-6EA4E876-05BA-40F6-B792-E6E1CD0AFF8D wds:Q57664903-72712FF3-DE2A-4715-84DB-221FD8D24EB6 wds:Q57664903-77566F67-BEBE-497A-91FF-00F34E2B1479 wds:Q57664903-7C147B4C-B654-47A1-B34C-B29608D72342 wds:Q57664903-8825B03B-A2DB-40BA-A676-1827A456EB6D wds:Q57664903-97E8D257-4EB6-4B3C-AB13-3AD717B2B9D0 wds:Q57664903-A94BCBDE-81CB-4660-B478-305B9766A853 wds:Q57664903-AB613A0C-B763-4F3E-98AC-C9E017FEA214 wds:Q57664903-B27FD491-60B4-496E-A0F7-973D655297E9 wds:Q57664903-BA510175-660A-4B74-B3B0-20F18A1F2B79 wds:Q57664903-C4F8D24E-5619-4A50-968C-66D95ADB2AFA wds:Q57664903-CAA9265C-388C-476A-BDB3-8916DFA787B2 wds:Q57664903-E22AE3F4-B49C-4215-999D-656478FEC6AD wds:Q57664903-E51B2C7D-3FA9-4377-AD5D-74BF8D4D5F6E wds:Q57664903-EE5842FA-E63D-44AB-95E2-8198957F9C3A wds:Q57664903-F7AEFCC2-E1EC-4411-AA62-858544648C6D wds:Q57664903-FB72C43C-8C78-4511-A859-B9E6E5BEBC0A
cites work	A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 P16 gene in uncultured tumours The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53 CDKN2A Variants in a Population-Based Sample of Queensland Families With Melanoma A cell cycle regulator potentially involved in genesis of many tumor types Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest Analysis of G1/S checkpoint regulators in metastatic melanoma Significant impact of promoter hypermethylation and the 540 C>T polymorphism of CDKN2A in cutaneous melanoma of the vertical growth phase A single nucleotide polymorphism in the 3?untranslated region of theCDKN2A gene is common in sporadic primary melanomas but mutations in theCDKN2B,CDKN2C,CDK4 andp53 genes are rare DNA methylation and the mechanisms of CDKN2A inactivation in transitional cell carcinoma of the urinary bladder The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology? Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population Frequency of homozygous deletion at p16/CDKN2 in primary human tumours p16 (CDKN2) is a major deletion target at 9p21 in bladder cancer. Deletion of the p16 and p15 Genes in Human Bladder Tumors Rates of p16 (MTS1) mutations in primary tumors with 9p loss Molecular alterations in bladder cancer Molecular and kinetic features of transitional cell carcinomas of the bladder: biological and clinical implications Mutations in the CDKN2A ( p16INK4a ) gene in microdissected sporadic primary melanomas Loss of heterozygosity at chromosome 9p21 (INK4-p14ARF locus): homozygous deletions and mutations in the p16 and p14ARF genes in sporadic primary melanomas MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p Selective deletion of exon 1 beta of the p19ARF gene in metastatic melanoma cell lines. Loss of heterozygosity on chromosome 9 and loss of chromosome 9 copy number are separate events in the pathogenesis of transitional cell carcinoma of the bladder Homozygous deletions but no sequence mutations in coding regions of p15 or p16 in human primary bladder tumors. Infrequent somatic mutation of the MTS1 gene in primary bladder carcinomas. Decreased expression of the p16/MTS1 gene without mutation is frequent in human urinary bladder carcinomas Single nucleotide polymorphism analyses of the human proliferating cell nuclear antigen (pCNA) and flap endonuclease (FEN1) genes
author name string	wds:Q57664903-6680C104-510D-4CC3-B459-5842C780A6C2 wds:Q57664903-AAB1AD64-3EF6-45E1-9CF8-7B355EE93CEB wds:Q57664903-C758A1A2-80DA-4A7C-BB27-D6217DCE689D wds:Q57664903-ED397AF3-082C-411C-B427-AE9E79AED7EC
author name string	Per Larsson Shigeru Sakano Petra Berggren Erik Onelöv
rdfs:label	Clinical course of bladder neoplasms and single nucleotide polymorphisms in theCDKN2Agene (en) Clinical course of bladder neoplasms and single nucleotide polymorphisms in theCDKN2Agene (nl)
skos:prefLabel	Clinical course of bladder neoplasms and single nucleotide polymorphisms in theCDKN2Agene (en) Clinical course of bladder neoplasms and single nucleotide polymorphisms in theCDKN2Agene (nl)
name	Clinical course of bladder neoplasms and single nucleotide polymorphisms in theCDKN2Agene (en) Clinical course of bladder neoplasms and single nucleotide polymorphisms in theCDKN2Agene (nl)
author	wds:Q57664903-39887E33-78AA-4367-BA9D-9A9383030CB4 wds:Q57664903-60DDE13A-8B59-411A-AEF3-764DAAF102DA wds:Q57664903-8395D9FE-B996-43BF-8F73-75129518A97C wds:Q57664903-B60FF1D3-3A82-41B9-828E-90E71EFD792D
author	Kari Hemminki Gunnar Steineck Rajiv Kumar Jan Adolfsson
title	wds:Q57664903-46BE9A96-B156-4C54-B015-CE3DDFCB15B0
title	Clinical course of bladder neoplasms and single nucleotide polymorphisms in theCDKN2Agene (en)
page(s)	wds:Q57664903-0D88C142-7748-4D29-8957-260D3ECFADA1
page(s)	98-103
instance of	wds:Q57664903-E5D99F8B-F84E-408E-A751-372E2DB56404
instance of	scholarly article
main subject	wds:Q57664903-5737111C-E24B-400D-ACE0-E2DA3E0A8361 wds:Q57664903-A25F03D9-E3B5-43EB-BDA2-F1BFFB84554C
main subject	cancer research single-nucleotide polymorphism
PubMed ID	wds:Q57664903-AA177CCA-2F8D-440F-B36F-0877EE828027
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/12532425
PubMed ID	12532425
published in	wds:Q57664903-77898917-3305-481F-AAC4-66FB614683C1

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