About: Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

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About: Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis Goto Sponge NotDistinct Permalink

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scholarly article by Anca Dorhoi et al published 20 December 2011 in European Journal of Immunology

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 2011 (uk) im Dezember 2011 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Anca Dorhoi et al published 20 December 2011 in European Journal of Immunology (en)
publication date	wds:Q57598527-AF8C9C9B-BD01-425B-BCBD-6FD8C9B3F595
publication date	2011-12-20 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57598527-049032A8-60C6-44D8-AC19-CDC3EBD4B212
language of work or name	English
cites work	wds:Q57598527-009C7458-E7F5-47F7-AD85-6E83A53EECD6 wds:Q57598527-00BA804B-A901-492B-8AEF-141F21E445A8 wds:Q57598527-10933DDB-8092-418D-982B-4CE8901FAB2C wds:Q57598527-14B18A60-A90C-4A48-8D5E-2560CD865A8D wds:Q57598527-19197FA8-4205-42FB-BF2C-9D7C30F37D6B wds:Q57598527-196DD1C4-24F7-4003-AC40-15CF31E0C7AF wds:Q57598527-1AA2AF6A-135B-49E3-B07B-6BBCCA923C33 wds:Q57598527-1BBB5E39-BF46-4969-A7DA-C41698F51255 wds:Q57598527-21011E79-999D-4A97-8EFD-FDFA83AB9958 wds:Q57598527-28118F4E-203F-477C-A56B-4C54EEC1178B wds:Q57598527-28621A61-DAF9-4B3E-A7F8-BAFCD5745FB0 wds:Q57598527-2EBC6762-7B4A-478A-A620-0672974FE9DD wds:Q57598527-37DCED74-822C-445E-9215-0F151FCAF582 wds:Q57598527-38681846-8578-4F45-B827-E32DBC0F47B8 wds:Q57598527-4238D9B6-7411-416C-A30E-ECD4887AC950 wds:Q57598527-4F2D98CA-46F7-4EAD-A769-82F62238F383 wds:Q57598527-55E766DA-F4FD-4008-AD43-6629CA9BC5D1 wds:Q57598527-5D36232D-9463-4B67-926F-9D00786379CD wds:Q57598527-5DA8E4BA-E72C-4635-981B-544F95DCE310 wds:Q57598527-5F84DA1D-2259-44E9-BEFC-A77752042E3C wds:Q57598527-669EB204-EDC6-455E-9AA6-27A616872FB7 wds:Q57598527-685E6A61-13B2-4465-98D7-3BC156C2761D wds:Q57598527-70F66E6F-6A6A-4FCF-9CB9-04EFA5376E3A wds:Q57598527-761C3FCF-696A-4932-8C6C-6DAAA1CCDF27 wds:Q57598527-78A64E57-5092-4BAC-8356-735A63789F07 wds:Q57598527-7F7D78ED-C366-4D35-89CE-19C3E659B5E7 wds:Q57598527-82A6E507-63A8-4A7D-84B2-426029E2541B wds:Q57598527-8958786D-53EF-4BD5-BB75-15F54FCC3B97 wds:Q57598527-8A12BFD3-B953-4E16-A4CF-CB027675BF2E wds:Q57598527-8C2B1127-6FC3-4805-B820-EB6615081AB6 wds:Q57598527-91F6882B-9A57-40CD-9AF3-34BE6837F2C1 wds:Q57598527-9316699E-A9C0-44FB-93D5-78DDF2E30F89 wds:Q57598527-93CC9243-DEC2-4199-A9D0-CC4063B0ACF5 wds:Q57598527-950AE04C-8A93-492C-9213-3A696E2E64D1 wds:Q57598527-96977BBE-27D9-4313-8A2A-65FFC60E15C5 wds:Q57598527-979DAC62-5AD7-44EE-9297-54251499AF21 wds:Q57598527-991A3A6D-4CB4-4A18-8EF6-82C3D2A9E3CA wds:Q57598527-A1559205-FEA4-476D-9E69-A9C8FA7A8513 wds:Q57598527-A80FF033-85AF-4278-8B2C-3E57EA218BC5 wds:Q57598527-A921E60A-B73C-466B-9B91-AFE08995B5CE wds:Q57598527-B4ACDC84-4D86-4C9A-98FE-A501D5688E52 wds:Q57598527-BA6771A2-9729-4A38-A89D-8D8B2933771F wds:Q57598527-BEC41A5B-EB8E-46B1-8572-25B14CD57D2D wds:Q57598527-C26CC1E1-58DA-4ABA-881D-1A6F9C5E8896 wds:Q57598527-C7D1850B-41E4-4C1E-B1BB-9EE60C053250 wds:Q57598527-CE9896F6-D39A-46E8-B509-7C0294548E97 wds:Q57598527-CF7A0911-BFF0-44E3-9BAD-DEDAA716F1B1 wds:Q57598527-D1801D4C-CDF5-4112-8AD1-AC2064D31CD3 wds:Q57598527-D9598311-34E6-4723-B221-3CBBD1BC16AE wds:Q57598527-DA99E47F-4137-45A9-B2E0-254AC5014967 wds:Q57598527-EABAF1E8-F9ED-42AD-AAFD-D20916194850 wds:Q57598527-F3395628-2479-42F8-BFAA-8458350EF0B2 wds:Q57598527-F6717A34-4D59-42BB-95A9-AA10C08A5A2E wds:Q57598527-FD1CF1A3-D09F-42BD-AF29-F5A9E5EBCCA0 wds:Q57598527-FE96B738-E399-4473-877C-372F15704CAB
cites work	Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells Altered cytokine production in mice lacking P2X(7) receptors A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion Cell-mediated immune responses in tuberculosis M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells Active caspase-1 is a regulator of unconventional protein secretion Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock ESX/type VII secretion systems and their role in host-pathogen interaction NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation Identification of a key pathway required for the sterile inflammatory response triggered by dying cells Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity IL-1beta processing in host defense: beyond the inflammasomes NALP3 is not necessary for early protection against experimental tuberculosis. Gout-associated uric acid crystals activate the NALP3 inflammasome Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression Interleukin-1 in the pathogenesis and treatment of inflammatory diseases Nonresolving inflammation Serine protease activity contributes to control of Mycobacterium tuberculosis in hypoxic lung granulomas in mice Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome Cutting Edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis Protective role of interleukin-1 in mycobacterial infection in IL-1 alpha/beta double-knockout mice Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death. Points of control in inflammation

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