About: Inhibition of WEE1 Suppresses the Tumor Growth in Laryngeal Squamous Cell Carcinoma

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About: Inhibition of WEE1 Suppresses the Tumor Growth in Laryngeal Squamous Cell Carcinoma Goto Sponge NotDistinct Permalink

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scholarly article by Meng-Ling Yuan et al published 2018 in Frontiers in Pharmacology

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description	wetenschappelijk artikel (nl) im Januar 2018 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована у 2018 (uk) scholarly article by Meng-Ling Yuan et al published 2018 in Frontiers in Pharmacology (en)
publication date	wds:Q57490219-8B7D529A-2E06-4E21-BDF6-A754B8BF206B
publication date	2018-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57490219-5C0D789D-9B62-4206-B14A-85271608FA0E
language of work or name	English
cites work	wds:Q57490219-030F5B36-50BB-4D2B-BA7E-56EA27B30A8C wds:Q57490219-0324DF8F-DF65-45DE-9BDC-E70F65D3C368 wds:Q57490219-08B092CA-7249-4587-BC59-5EC59092333E wds:Q57490219-0BABCC19-B37E-4E64-B98B-CB5A4202543C wds:Q57490219-0E676B95-7C5B-4524-8788-21CA271E4CE2 wds:Q57490219-1CE0D82D-AFE2-4B89-9518-10585CFBE5E0 wds:Q57490219-220496F3-0EFB-4E55-BCCA-1E9413C61DF8 wds:Q57490219-2349025E-694B-454B-8480-82810EE9155E wds:Q57490219-2419136F-82C5-4A09-8EB8-BCF77DE19DE6 wds:Q57490219-2B807A41-F2C6-4E7E-ADB2-5AD233A18BA9 wds:Q57490219-3202FDA4-7F50-466A-B62E-031C6698AFE0 wds:Q57490219-3FD97F68-A231-4230-84C3-441B194EE2A0 wds:Q57490219-424245F7-1F4E-4C4F-822E-771A3E50FBF7 wds:Q57490219-457EAF9C-EDEF-46DC-9ED8-3A84E79B2E3A wds:Q57490219-483A3D89-08EF-49F2-B21E-334E760BF968 wds:Q57490219-4DD15F30-D8E2-4948-A38A-EEEECF04632B wds:Q57490219-5B6262E7-CCA2-406E-B2FF-9DA70EA98F91 wds:Q57490219-79AB41CE-ADDA-4A2F-9C5E-A68752B04CBC wds:Q57490219-7DFBF553-C31B-4C9C-BF3A-C751BE5E7A6A wds:Q57490219-7F060D98-D402-4499-8158-6FEA9B546FEC wds:Q57490219-82FBE478-BBEB-4F37-B569-6AB04BE28657 wds:Q57490219-8327B7A5-34B8-448C-967B-FD2C3E94C930 wds:Q57490219-AB4C5E52-6667-4D5C-8248-AF6B7E30DC4D wds:Q57490219-B036B32A-1A64-48D4-9B2A-A177985A6A2C wds:Q57490219-B3A29776-BA55-4D9D-8D7E-0392005763C8 wds:Q57490219-C9E06EEE-727D-439A-86E6-3A6FBA0FC9E0 wds:Q57490219-CAE5BD00-9E91-4A50-BD30-B1529A6174A0 wds:Q57490219-D16B52FC-CFA5-444B-ADF5-73349E29B963 wds:Q57490219-DF79C13A-6DEB-446A-A08D-BA29FA8132C8 wds:Q57490219-E8A6B1D5-FD18-41E5-A49F-20B0F04851FE wds:Q57490219-EC6DA533-5A35-459D-AAA5-CCF8CA296945 wds:Q57490219-F3CB55DC-22EA-47CD-BC71-5E9F577762BE
cites work	Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? ROS function in redox signaling and oxidative stress Reactive oxygen species (ROS) and cancer: Role of antioxidative nutraceuticals Reactive oxygen species in cancer cells: live by the sword, die by the sword. Production of reactive oxygen species in response to replication stress and inappropriate mitosis in fission yeast MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence Preclinical evaluation of the WEE1 inhibitor MK-1775 as single-agent anticancer therapy The antioxidant paradox: less paradoxical now? Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair Targeting WEE1 Kinase in Cancer Wee1 inhibition by MK-1775 leads to tumor inhibition and enhances efficacy of gemcitabine in human sarcomas Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading Cancer statistics, 2018. Wee1 is a novel independent prognostic marker of poor survival in post-chemotherapy ovarian carcinoma effusions. High expression of wee1 is associated with malignancy in vulvar squamous cell carcinoma patients Expression and prognostic value of the WEE1 kinase in gliomas. The prognostic value of preoperative neutrophils, platelets, lymphocytes, monocytes and calculated ratios in patients with laryngeal squamous cell cancer Reactive Oxygen and Nitrogen Species in Carcinogenesis: Implications of Oxidative Stress on the Progression and Development of Several Cancer Types Mechanisms of a novel anticancer therapeutic strategy involving atmospheric pressure plasma-mediated apoptosis and DNA strand break formation Molecular Pathways: Targeting the Protein Kinase Wee1 in Cancer. MiR-194 functions as a tumor suppressor in laryngeal squamous cell carcinoma by targeting Wee1 The Roles of ROS in Cancer Heterogeneity and Therapy. WEE1 Kinase Inhibitor AZD1775 Has Preclinical Efficacy in LKB1-Deficient Non-Small Cell Lung Cancer Upregulation of WEE1 is a potential prognostic biomarker for patients with colorectal cancer Suppression of Sirt1 sensitizes lung cancer cells to WEE1 inhibitor MK-1775-induced DNA damage and apoptosis. Improvement of multivariate image analysis applied to quantitative structure-activity relationship (QSAR) analysis by using wavelet-principal component analysis ranking variable selection and least-squares support vector machine regression: QSAR stu Expression and clinical significance of Wee1 in colorectal cancer A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells A Mini-Review of Reactive Oxygen Species in Urological Cancer: Correlation with NADPH Oxidases, Angiogenesis, and Apoptosis
author name string	wds:Q57490219-1F23BB3F-A56C-4BF8-8928-B31F0927A9F6 wds:Q57490219-2200E04D-2956-4C32-82E9-2B5E0ABEE0C6 wds:Q57490219-24CE041C-86A3-4BFC-ABA4-A5D31023EB19 wds:Q57490219-2B98D166-58C2-4B37-B8D0-5F248F2C589A wds:Q57490219-2EB26CB0-0DED-454B-98CF-0978DDF50E33 wds:Q57490219-3BBEA585-C405-4EE7-801C-75B48337A7DF wds:Q57490219-3BF521FB-76A3-4211-BE39-0CFFB22563F4 wds:Q57490219-4E7E3579-1C0A-4D40-ADC2-868959A7409A wds:Q57490219-5026149E-2EF0-4E0C-83AC-D72515A1B75F wds:Q57490219-50E77C59-4F38-4B9E-9FA5-4A9084FB1908 wds:Q57490219-8528D29D-48FD-4747-93F1-94CE69FB4904 wds:Q57490219-9BD95A2D-0955-49C3-B986-CCC1AED297B2 wds:Q57490219-C72A2D6E-59D5-409E-9039-602999B7C2EF wds:Q57490219-D56FA78E-34AC-4745-8F3A-2A7B8B9C6BDD wds:Q57490219-F7020A87-B645-4E55-8C28-81F00E8E3B7A
author name string	Hui Liu Yang Yang Kun Wang Yao Li Pei Li Qi-Wei Jiang Jin Ye Jin-Ming Di Zhi Shi Jia-Rong Huang Meng-Ning Wei An-Kui Yang

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