About: Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion

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About: Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion Goto Sponge NotDistinct Permalink

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description	article (en) հոդված (hy) wetenschappelijk artikel (nl) article scientifique publié en 2005 (fr) наукова стаття, опублікована в грудні 2005 (uk) im September 2005 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q57396518-888AE7C3-5B50-4CDE-AD8E-4D7ADCCAA454
publication date	2005-09-02 00:00:00Z (xsd:dateTime)
cites work	wds:Q57396518-34EB499A-B212-4904-BAC8-FAD48D1B3764 wds:Q57396518-43B2EB10-C492-4D16-A050-FFCCE2C1EF8E wds:Q57396518-46B10EBC-4CC5-44F2-A246-6E35BE8DEA65 wds:Q57396518-50F0B839-AD00-4719-9217-E3B22FE20EFE wds:Q57396518-5ECF4EE4-E474-463C-8F43-14D3D6C1625F wds:Q57396518-6960CE92-5013-449F-86EA-D124E4A4152D wds:Q57396518-72D42FAE-1D30-4DDD-9C86-84CD62906FFA wds:Q57396518-91D516FB-5C31-4965-9CE6-91BC0ADDF205 wds:Q57396518-929B3C65-7A38-4DCE-AB36-A0C7F33A05FD wds:Q57396518-9AD24D2B-25B8-4845-8FD3-52931088C1D0 wds:Q57396518-A7654B3A-4C4E-49FB-9BCB-E910BA8109D1 wds:Q57396518-C6448A17-D99C-45FA-A693-D98116F6401D wds:Q57396518-D60C7ED2-0A1F-4E97-8003-F608E1EAACE8 wds:Q57396518-D6B7F31E-E033-4D65-87C1-0064F70EE690 wds:Q57396518-E113572C-CAAE-406C-8445-1BAB10746FAB wds:Q57396518-F76003E4-80E7-42C8-B965-2DB0C89957E4 wds:Q57396518-FEB91389-87E8-42D3-A45C-CCCD88117147
cites work	Targeted inhibition of p38 mitogen-activated protein kinase antagonizes cardiac injury and cell death following ischemia-reperfusion in vivo An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha Ischemic preconditioning preserves connexin 43 phosphorylation during sustained ischemia in pig hearts in vivo p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system Disruption of a single copy of the p38alpha MAP kinase gene leads to cardioprotection against ischemia-reperfusion. Inconsistent relation of MAPK activation to infarct size reduction by ischemic preconditioning in pigs. Characterization of apoptosis signal transduction pathways in HL-5 cardiomyocytes exposed to ischemia/reperfusion oxidative stress model Murine cardiac function: a cautionary tail. Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia Mitogen-activated protein kinases in the heart Role of phasic dynamism of p38 mitogen-activated protein kinase activation in ischemic preconditioning of the canine heart. Inhibition of p38 MAPK alpha/beta reduces ischemic injury and does not block protective effects of preconditioning
author name string	wds:Q57396518-1DB301B6-826E-4F7E-8033-CA2E2C845C1F wds:Q57396518-23A08BCF-BCF7-4C68-92BC-D9883079E0DC wds:Q57396518-7410E6C8-B06C-4CF9-971B-1D2BE7CA4766 wds:Q57396518-97A600DC-6C23-47BE-92CC-2594F3E9E01B wds:Q57396518-9D819C0A-63EB-4A6F-988A-35B1374F6B4F wds:Q57396518-A2045D21-FE99-40A7-9FCF-EDD6F3F2B7A3 wds:Q57396518-B2736779-CA54-40C2-B184-B8EA276A0FE5
author name string	Robert A Kaiser Jeffrey M Pearl Jefferson M Lyons Jodie Y Duffy Kelly M McLean Connie J Wagner Timothy P O'Neill
rdfs:label	Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion (en) Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion (nl)
skos:prefLabel	Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion (en) Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion (nl)
name	Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion (en) Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion (nl)
author	wds:Q57396518-8FA6E432-5BB8-491D-9D71-450CA056301A
author	Jeffery D. Molkentin
title	wds:Q57396518-E45128E8-6EB5-4D7E-8792-67A66BBC2B43
title	Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion (en)
page(s)	wds:Q57396518-22FF13DF-83AD-4886-A7BE-F66BB904CBF3
page(s)	H2747-51
instance of	wds:Q57396518-7CB901C0-CD39-4473-858B-F3CC49FC0D9B
instance of	scholarly article
main subject	wds:Q57396518-1A68B0C0-48A7-409F-80C9-A5C97C83336F wds:Q57396518-4F37B2B2-BECB-48D7-AA92-B29A3A74B3CC
main subject	myocardial infarction pig
PubMed ID	wds:Q57396518-0B610750-B436-44E5-BBF0-E5A2EB53CD32
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16143643
PubMed ID	16143643
published in	wds:Q57396518-BCC01FD4-659E-440E-98C5-2AEB1199517C
published in	American Journal of Physiology Heart and Circulatory Physiology
issue	wds:Q57396518-E7A7B422-0227-4C91-9DB8-B783FBEDA940
volume	wds:Q57396518-1724ACA4-C4C3-4F53-88F6-5C5C40456E3C
issue	6
volume	289
DOI	wds:Q57396518-C64CB04F-DF13-40DC-A59D-29C230807627
DOI	http://dx.doi.org/10.1152/AJPHEART.01280.2004
DOI	10.1152/AJPHEART.01280.2004
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q57396518
is cites work of	A thrombospondin-dependent pathway for a protective ER stress response Mitogen-activated protein kinases in heart development and diseases Kinase inhibitors for cardiovascular disease Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale The role of proteomics in clinical cardiovascular biomarker discovery. Emerging role of MAP kinase pathways as therapeutic targets in COPD. Role of p38 mitogen-activated protein kinase in cardiac remodelling Role of p38 inhibition in cardiac ischemia/reperfusion injury TNF-α upregulates Fgl2 expression in rat myocardial ischemia/reperfusion injury. Guidelines for translational research in heart failure. Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage

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