About: Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

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scientific article published in Nature

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) article publié dans la revue scientifique Nature (fr) im September 2006 veröffentlichter wissenschaftlicher Artikel (de) নেচারে প্রকাশিত বৈজ্ঞানিক প্রবন্ধ (bn) scientific article published in Nature (en) наукова стаття, опублікована в Nature у вересні 2006 (uk)
publication date	wds:Q57277034-8AEB8F9E-19E1-4574-B820-A1A7F5D85625
publication date	2006-09-06 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57277034-58E03F84-A229-40DE-AAB1-41DC5599B466
language of work or name	English
exact match	wds:Q57277034-73F07608-6C59-485D-AA85-CB01699FAC29
exact match	https://scigraph.springernature.com/pub.10.1038/nature05159
cites work	wds:Q57277034-000FB736-1C1C-4657-89FA-1B3BA8A64042 wds:Q57277034-01C7981D-1398-4EAF-B59F-844E83C66657 wds:Q57277034-043D4742-BF6C-41D3-BCF7-F204523575AB wds:Q57277034-157AB9E5-6F8E-4CF8-8E44-1C8F08613A6B wds:Q57277034-16C4883B-5F2B-4BBD-8C37-1C598F834B1F wds:Q57277034-230E80C1-BBE7-44B3-BEFF-74B34744ABF2 wds:Q57277034-2BEEE62A-CE40-4DC6-AAD7-9A2978F3911B wds:Q57277034-2F49737F-405C-48CD-AF67-D61116F10DFF wds:Q57277034-3CF3772A-DD16-4128-914E-AE8DBF0DE7EC wds:Q57277034-3FD36608-FECF-4AFB-8F49-17DBD5F391A4 wds:Q57277034-40345735-8A38-4A5C-B05D-E051CA225962 wds:Q57277034-40FB6240-6557-4596-8575-CDFF6834203A wds:Q57277034-543F6041-A3A5-4980-AD33-831C07963A47 wds:Q57277034-700EFC61-C4C7-41B1-A3D8-80D8683A34DC wds:Q57277034-72A33A88-49E3-4072-90BC-A193943834CE wds:Q57277034-75EE43A0-C45E-4348-9021-B85042C6F8B8 wds:Q57277034-7A09C38C-2DC5-4B6D-986B-C98A83946279 wds:Q57277034-7BE2B828-B205-45D6-A17A-AC7ACDF1BE1E wds:Q57277034-7C430658-96ED-425D-9469-090B269762A1 wds:Q57277034-8FAF38D2-5684-40FC-8D87-0424BC116BFC wds:Q57277034-A03B291A-7DE0-4E74-9966-F76A772BFB5D wds:Q57277034-A362F3D2-9DF4-40F7-8D28-FC4ED15886FD wds:Q57277034-A3B4F678-9DB1-432B-9FF3-93E35C441A87 wds:Q57277034-AB23C0F1-FE9C-4F59-8660-4899E8E5E3BB wds:Q57277034-B7D439B0-D54E-45F6-961A-18477AED2654 wds:Q57277034-C0D1B252-6E2E-425C-9FE6-2F14471CB7DE wds:Q57277034-C24A2B9F-78F7-4D8F-AA5E-41F5BFA02C39 wds:Q57277034-C2DF2073-AAA1-4C0B-A704-A69957046CEE wds:Q57277034-D97E64E5-1987-4B50-B033-A178A825D487 wds:Q57277034-E078932B-1321-4960-81CE-67ED3E835714 wds:Q57277034-F3F3CAF0-9381-4FB3-9B8B-C2B4394FA95E wds:Q57277034-FF8023BC-58E0-4349-8FA0-FE6286B39D86
cites work	Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor p16(MTS-1/CDKN2/INK4a) in cancer progression Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization Development and aging of primitive hematopoietic stem cells in BALB/cBy mice Genetic regulation of primitive hematopoietic stem cell senescence Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing Rejuvenation of aged progenitor cells by exposure to a young systemic environment Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. Ink4a/Arf links senescence and aging SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity p16INK4a induces an age-dependent decline in islet regenerative potential Hematopoietic stem cell quiescence maintained by p21cip1/waf1 In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein Ink4a/Arf expression is a biomarker of aging Increased expression of p16(INK4a) and p27(Kip1) cyclin-dependent kinase inhibitor genes in aging human kidney and chronic allograft nephropathy Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure The aging of hematopoietic stem cells Little evidence for developmental plasticity of adult hematopoietic stem cells. Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo Decline in colony-forming ability of marrow cells subjected to serial transplantation into irradiated mice A limited role for p16Ink4a and p19Arf in the loss of hematopoietic stem cells during proliferative stress The fate of serially transplanted bone marrow cell populations from young and old donors Normal Function of Transplanted Mouse Erythrocyte Precursors for 21 Months beyond Donor Life Spans
author name string	wds:Q57277034-0F3A8176-72A4-4F6D-A2DC-5729402A1A9E wds:Q57277034-4B208E67-CB17-4F68-A3FC-9006B460A8BB wds:Q57277034-65A9F0B4-7FEE-4E65-98A0-3DE0873A7161 wds:Q57277034-95FAD335-428D-4B34-976E-AD893CFCAAD8 wds:Q57277034-ACF2116E-E8F1-4598-B0E7-5B467C886B2E wds:Q57277034-DFBC9C06-2EDC-4827-92E8-F3613A7F08CF wds:Q57277034-FC7C1F95-9B96-494A-BAAA-A899EA75A8F8
author name string	Tao Cheng David M Dombkowski Heather E Fleming Michael T Waring Yoriko Saito Randolf Forkert Viktor Janzen
rdfs:label	Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a (en) Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a (nl)
skos:prefLabel	Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a (en) Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a (nl)
name	Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a (en) Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a (nl)
author	wds:Q57277034-5D80AE60-25DA-46B0-B8E2-25686A6E1BEF wds:Q57277034-6C10FBB9-9777-4219-A26B-26C9BE6D5EFB

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