About: Vav1 Controls DAP10-Mediated Natural Cytotoxicity by Regulating Actin and Microtubule Dynamics

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About: Vav1 Controls DAP10-Mediated Natural Cytotoxicity by Regulating Actin and Microtubule Dynamics Goto Sponge NotDistinct Permalink

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rdf:type	Item
description	article (en) wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2006 (uk) im August 2006 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q57275873-C8260C2B-0AB7-4480-9DBC-0984B8A423B9
publication date	2006-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57275873-C7444574-68AA-4ACE-8E11-7313D1102B91
language of work or name	English
author name string	wds:Q57275873-29BA1B3F-31E3-44A4-B234-337459876AA0 wds:Q57275873-355152ED-A6FE-4FC6-8D84-32E2B590A4CA wds:Q57275873-847D019C-CF9E-4AAB-8963-FB825D921F67 wds:Q57275873-E18A2752-43B0-443C-855A-781A615AF51A
author name string	Daniel B Graham Karry Brim Ana V Miletic Tracie Kloeppel
rdfs:label	Vav1 Controls DAP10-Mediated Natural Cytotoxicity by Regulating Actin and Microtubule Dynamics (en) Vav1 Controls DAP10-Mediated Natural Cytotoxicity by Regulating Actin and Microtubule Dynamics (nl)
skos:prefLabel	Vav1 Controls DAP10-Mediated Natural Cytotoxicity by Regulating Actin and Microtubule Dynamics (en) Vav1 Controls DAP10-Mediated Natural Cytotoxicity by Regulating Actin and Microtubule Dynamics (nl)
name	Vav1 Controls DAP10-Mediated Natural Cytotoxicity by Regulating Actin and Microtubule Dynamics (en) Vav1 Controls DAP10-Mediated Natural Cytotoxicity by Regulating Actin and Microtubule Dynamics (nl)
author	wds:Q57275873-1800EA5F-3343-49F5-9F6D-D6DB1302BA35 wds:Q57275873-528FFA41-970E-4E72-898A-8BE8A7B46AE5 wds:Q57275873-6DF0BCA6-966E-4EBB-A6A8-BFDC56B311A7 wds:Q57275873-8DE76236-D63F-40D5-9B97-7BBF9DAB4AB5 wds:Q57275873-9D21F21D-7E58-4047-A2DE-2AF2DF705EE5 wds:Q57275873-ABE18A50-7B0A-44C3-9CC0-6E4AA75221A1 wds:Q57275873-ADA51B29-F68C-4F4A-9DF4-A49BB55DE7B0
author	Emanuele Giurisato Marina Cella Marco Colonna Andrey Shaw Toshiyuki Takai Wojciech Swat Keiko Fujikawa
title	wds:Q57275873-3C6599A7-A4A1-429D-AB12-625D1F5CB1D7
title	Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics (en)
page(s)	wds:Q57275873-E129B7C8-A49E-4C16-AC5F-BECD962C74B3
page(s)	2349-2355
instance of	wds:Q57275873-2C4A5F61-C82F-466D-B16D-C8D05901AB6A
instance of	scholarly article
main subject	wds:Q57275873-EBD9FB51-25B5-4D85-9C26-04041ED16114
main subject	cytotoxicity
PubMed ID	wds:Q57275873-BB5DEA70-A079-4BB8-B97F-041EA00C5DA7
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16887996
PubMed ID	16887996
published in	wds:Q57275873-BAAD63A0-4A5B-4817-8A5A-59C6AA36DDAB
published in	Journal of Immunology
issue	wds:Q57275873-76084E44-40A7-4E59-9F07-2DDA6623E8B9
volume	wds:Q57275873-117D2577-E751-46FE-AA82-FFA719B88CF0
issue	4
volume	177
DOI	wds:Q57275873-36B039B3-AF97-4C86-967C-5F70807C3F79
DOI	http://dx.doi.org/10.4049/JIMMUNOL.177.4.2349
DOI	10.4049/JIMMUNOL.177.4.2349
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q57275873
is cites work of	Up on the tightrope: natural killer cell activation and inhibition Natural killer cell signal integration balances synapse symmetry and migration Effect of NKG2D ligand expression on host immune responses Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis Expression profiling reveals a positive regulation by mPer2 on circadian rhythm of cytotoxicity receptors: Ly49C and Nkg2d. NK cell-activating receptors require PKC-theta for sustained signaling, transcriptional activation, and IFN-gamma secretion. Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse Navigating barriers: the challenge of directed secretion at the natural killer cell lytic immunological synapse. Vav proteins are necessary for correct differentiation of mouse cecal and colonic enterocytes. Cell biological steps and checkpoints in accessing NK cell cytotoxicity Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy Formation and function of the lytic NK-cell immunological synapse Controlling natural killer cell responses: integration of signals for activation and inhibition PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion. Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase β2 integrin induces TCRζ-Syk-phospholipase C-γ phosphorylation and paxillin-dependent granule polarization in human NK cells Natural killer cells and cancer: regulation by the killer cell Ig-like receptors (KIR). A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse Vav1 acidic region tyrosine 174 is required for the formation of T cell receptor-induced microclusters and is essential in T cell development and activation Vav/Phospholipase Cgamma2-mediated control of a neutrophil-dependent murine model of rheumatoid arthritis B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin. PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15. Signal transduction during activation and inhibition of natural killer cells. Vav1-phospholipase C-γ1 (Vav1-PLC-γ1) pathway initiated by T cell antigen receptor (TCRγδ) activation is required to overcome inhibition by ubiquitin ligase Cbl-b during γδT cell cytotoxicity The central role of the cytoskeleton in mechanisms and functions of the NK cell immune synapse. Complementary phosphorylation sites in the adaptor protein SLP-76 promote synergistic activation of natural killer cells The role of HLA-G in immunity and hematopoiesis. Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity Dephosphorylation of the adaptor LAT and phospholipase C-γ by SHP-1 inhibits natural killer cell cytotoxicity NKG2D triggers cytotoxicity in murine epidermal γδ T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathway. Rapid activation receptor- or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signaling Redirected Primary Human Chimeric Antigen Receptor Natural Killer Cells As an "Off-the-Shelf Immunotherapy" for Improvement in Cancer Treatment DAP10 associates with Ly49 receptors but contributes minimally to their expression and function in vivo Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity. The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy Lytic granule polarization, rather than degranulation, is the preferred target of inhibitory receptors in NK cells SHP-2 expression negatively regulates NK cell function Granule-Dependent Natural Killer Cell Cytotoxicity to Fungal Pathogens. Actin retrograde flow controls natural killer cell response by regulating the conformation state of SHP-1. NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment

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