About: Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

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About: Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance Goto Sponge NotDistinct Permalink

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article by Yongsheng Li et al published November 1999 in Nature Medicine

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в листопаді 1999 (uk) im November 1999 veröffentlichter wissenschaftlicher Artikel (de) article by Yongsheng Li et al published November 1999 in Nature Medicine (en)
publication date	wds:Q57202280-2F9C9ACA-67B6-45FB-BF81-025FAB0E35F5
publication date	1999-11-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57202280-A68571ED-4F17-461E-81A0-D3A7E72C6005
language of work or name	English
exact match	wds:Q57202280-97771F6D-4C6D-49BA-A65A-5F46D64999B3
exact match	https://scigraph.springernature.com/pub.10.1038/15256
cites work	wds:Q57202280-02EA80D5-8F8B-47B5-9FCF-20C310024AC8 wds:Q57202280-08F8674C-ED0C-4873-A569-FD64845FBFA7 wds:Q57202280-0BF43A3E-BA28-42B1-AB2B-20CB001E0607 wds:Q57202280-12B96331-ECBB-4BE0-86F8-E104BF251638 wds:Q57202280-13DF70AD-B6F3-470E-83C5-B3C7FCECEC2C wds:Q57202280-19F3F6A3-3455-4353-A5DF-44A81860981A wds:Q57202280-4E17692C-A438-4570-B6FA-3188CDA682FE wds:Q57202280-51A16D4C-E314-404E-9B92-8163675C1F4C wds:Q57202280-6579CDDF-5F1A-4896-A29E-A50FAB69D399 wds:Q57202280-6965FFC7-D6C9-4E23-A329-B7EED7A89564 wds:Q57202280-8BF1EF17-BB0A-43DC-80E7-713D8FFFE092 wds:Q57202280-A99B38AE-68C8-42FA-A77D-5D842CDCFA93 wds:Q57202280-AE060883-EBF7-4439-AF8B-66015A4D26C2 wds:Q57202280-EACB9066-8A0E-40E4-A7CE-57C7B4EF29AC wds:Q57202280-F018A2E3-3B66-46F2-8041-3BC779E958BF
cites work	The mechanism of action of cyclosporin A and FK506 Lymphocyte development from stem cells Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response Immunopharmacology of rapamycin Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin Presentation and recognition of major and minor histocompatibility antigens CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg Infectious tolerance. Chimerism and central tolerance Cyclosporin A blocks apoptosis by inhibiting the DNA binding activity of the transcription factor Nur77.
author name string	wds:Q57202280-0FF571BF-1CE4-41D0-8ABB-26640FD8F06B wds:Q57202280-28D1A448-BAE7-44AE-B561-5877E1AE6FA7 wds:Q57202280-35EFEEF6-AFEC-4CF6-945A-15763C1B3C12 wds:Q57202280-8E4C05E4-64B3-4373-8473-2A073A1464D9 wds:Q57202280-98DD6581-D92D-4C77-819B-79325E5D9027 wds:Q57202280-BD1DD963-3C26-41E3-B0D8-FED1A7D45837
author name string	Xin Xiao Zheng Laurence A. Turka Andrew D. Wells Yongsheng Li Xian Chang Li Terry B. Strom
rdfs:label	Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance (en) Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance (nl)
skos:prefLabel	Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance (en) Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance (nl)
name	Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance (en) Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance (nl)
author	wds:Q57202280-A55E777D-CFF9-4D10-8AB9-3AB73A74452C
author	Xian C. Li
title	wds:Q57202280-39B9AF54-1396-4138-AA7A-8A90338A235F
title	Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance (en)
page(s)	wds:Q57202280-4D23441F-3292-4FA8-B430-3CFA2B8B130C
page(s)	1298-1302
instance of	wds:Q57202280-89521DE9-2ED3-4287-9E66-F4546B1F5A87
instance of	scholarly article
main subject	wds:Q57202280-EFC83CED-B995-45BC-A9C3-5BBE1777B0D8
main subject	apoptotic process
PubMed ID	wds:Q57202280-99F78459-32E2-4CD2-AF90-29637C30DD7F
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10545997
PubMed ID	10545997
published in	wds:Q57202280-172E6D38-B649-4B5B-A9E1-0B57632A380D
published in	Nature Medicine
issue	wds:Q57202280-7EF7F0E5-DAB5-4A53-8219-915734A319BF
volume	wds:Q57202280-C13B4651-6C5C-4F32-9A14-BAB0D71BCF0C
issue	11
volume	5
DOI	wds:Q57202280-9415E4ED-5464-430A-AD3D-080678C5488F
DOI	http://dx.doi.org/10.1038/15256
DOI	10.1038/15256
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q57202280
is cites work of	Homeostatic proliferation is a barrier to transplantation tolerance Neutralizing IL-7 promotes long-term allograft survival induced by CD40/CD40L costimulatory blockade. Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28−/− mice Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells The two faces of heterologous immunity: protection or immunopathology Ethnicity greatly influences cytokine gene polymorphism distribution Memory T-cell-specific therapeutics in organ transplantation Challenges to achieving clinical transplantation tolerance Renal transplantation using belatacept without maintenance steroids or calcineurin inhibitors. The complementary roles of deletion and regulation in transplantation tolerance Clinical trials of transplant tolerance: slow but steady progress Tolerogenic therapies in transplantation. Clinical transplantation tolerance In search of the elusive Holy Grail: the mechanisms and prospects for achieving clinical transplantation tolerance. Tregs and transplantation tolerance Organ transplantation--how much of the promise has been realized? CTLA-4 up-regulation plays a role in tolerance mediated by CD45.

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