About: A human T cell-specific cDNA clone (YT16) encodes a protein with extensive homology to a family of protein-tyrosine kinases

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scholarly article by Yasuhiro Koga et al published 1986 in European Journal of Immunology

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в 1986 (uk) article scientifique publié en 1986 (fr) im Januar 1986 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Yasuhiro Koga et al published 1986 in European Journal of Immunology (en)
publication date	wds:Q57201383-907DCE42-6F7F-4DAE-ADEC-705FF8CA7DD6
publication date	1986-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57201383-BEE4B161-E0AC-42C3-B554-CEB7167EBA99
language of work or name	English
cites work	wds:Q57201383-7C27671B-126C-47A2-8BA2-159A1177D89C wds:Q57201383-8B4DE44B-CA84-4215-870B-964B29011815 wds:Q57201383-92857979-2059-4019-A01A-A3F2C97E8F15 wds:Q57201383-94CD3CE5-8FD9-43A6-AA7E-076DDF9F4B45 wds:Q57201383-9A895A99-0381-445E-9299-B8A90171448F wds:Q57201383-B858DEC8-FC8F-4DB6-8580-41BEA1C3E66D wds:Q57201383-CB8562EF-C17D-4B0C-932D-309F7DA819AE wds:Q57201383-CF7BA200-DDBB-4C83-8289-7FA086636497 wds:Q57201383-FF19918B-02EC-40A0-93C8-E553BC291FE3
cites work	Avian sarcoma virus Y73 genome sequence and structural similarity of its transforming gene product to that of Rous sarcoma virus Protein-tyrosine kinases A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion. A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA. Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus High tyrosine-specific protein kinase activity in normal human peripheral blood lymphocytes. Tyrosine phosphorylation in human T lymphoma cells
author name string	wds:Q57201383-271BC8D5-32C9-4A87-B593-01E3B18DC940 wds:Q57201383-346DD93E-09DA-40C5-89FD-731840590533 wds:Q57201383-42E5E5DC-5520-4EBE-BED0-58CE59B8182E wds:Q57201383-4F81BE9C-0C87-46D4-9F23-AE042CAAD3C9 wds:Q57201383-8D116901-9013-41EC-AD8E-4E1E4F1A3B97 wds:Q57201383-BDE3639B-96D0-45F5-9208-A30D6500394D wds:Q57201383-C36895AD-49DC-47DD-9411-DC2EF41994AD
author name string	Yusuke Yanagi Tak W. Mak Yasunobu Yoshikai Rosanne Spolski Yasuhiro Koga Nicolette Caccia Barry Toyonaga
rdfs:label	A human T cell-specific cDNA clone (nl) A human T cell-specific cDNA clone (YT16) encodes a protein with extensive homology to a family of protein-tyrosine kinases (en)
skos:prefLabel	A human T cell-specific cDNA clone (nl) A human T cell-specific cDNA clone (YT16) encodes a protein with extensive homology to a family of protein-tyrosine kinases (en)
name	A human T cell-specific cDNA clone (nl) A human T cell-specific cDNA clone (YT16) encodes a protein with extensive homology to a family of protein-tyrosine kinases (en)
title	wds:Q57201383-5A2A786A-1181-458D-8A0B-EBF970ED2E45
title	A human T cell-specific cDNA clone (YT16) encodes a protein with extensive homology to a family of protein-tyrosine kinases (en)
page(s)	wds:Q57201383-4E90DC28-75C7-417A-9F0B-F8926A283C0D
page(s)	1643-1646
instance of	wds:Q57201383-ED1136E0-B1B8-48DA-ABD3-2174863E02E8
instance of	scholarly article
main subject	wds:Q57201383-E1AEAB4D-AA0F-4E07-95BB-84300DAF90F6
main subject	immunology
PubMed ID	wds:Q57201383-0D13386C-E2E1-4407-8597-3715EB4F8FDA
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/3493153
PubMed ID	3493153
published in	wds:Q57201383-49EC272A-CE90-414A-8E1D-75AAE7BE8223
published in	European Journal of Immunology
issue	wds:Q57201383-11A93F92-089F-4601-92D7-44DCB8ED77D1
volume	wds:Q57201383-81BCA2B8-75FB-45CB-9ACD-34F20B6A9CF9
issue	12
volume	16
DOI	wds:Q57201383-7BCD1E80-E4F7-4829-8F86-BB5F4988D9A1
DOI	http://dx.doi.org/10.1002/EJI.1830161229
DOI	10.1002/EJI.1830161229
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q57201383
is cites work of	A conserved helix motif complements the protein kinase core 1 Protein kinase classification Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function Activated lck tyrosine protein kinase stimulates antigen-independent interleukin-2 production in T cells Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase Structure of the murine lck gene and its rearrangement in a murine lymphoma cell line The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity Chromosomal translocations joining LCK and TCRB loci in human T cell leukemia Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site Physical and functional association of p56lck with Fc gamma RIIIA (CD16) in natural killer cells Profound block in thymocyte development in mice lacking p56lck Recognition of the Lck tyrosine kinase as a tumor antigen by cytotoxic T lymphocytes of cancer patients with distant metastases Selective expression of alternative lck mRNAs in human malignant cell lines The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5 Two lck transcripts containing different 5' untranslated regions are present in T cells A novel human tyrosine kinase gene inducible in T cells by interleukin 2 Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changes Association between mitogen-activated protein kinase and the zeta chain of the T cell receptor (TcR) with the SH2,3 domain of p56lck. Differential regulation by TcR cross-linking Expression of CD4-Like Structure on Murine Egg Vitelline Membrane and Its Signal Transductive Roles Through p56lckin Fertilization Transcriptional activation of lck by retrovirus promoter insertion between two lymphoid-specific promoters. Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells High levels of heterodisperse RNAs accumulate in T cells infected with human immunodeficiency virus and in normal thymocytes Requirement for tyrosine kinase p56lck for thymic development of transgenic gamma delta T cells Expression of lineage-restricted protein tyrosine kinase genes in human natural killer cells The lymphocyte-specific protein tyrosine kinase p56lck is hyperphosphorylated on serine and tyrosine residues within minutes after activation via T cell receptor or CD2 Identification of Lck-derived peptides capable of inducing HLA-A2-restricted and tumor-specific CTLs in cancer patients with distant metastases Mouse monoclonal antibodies that specifically recognize an amino-terminal epitope of p56lck protein tyrosine kinase.

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