About: Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement

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About: Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement Goto Sponge NotDistinct Permalink

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scientific article published on 16 November 2012

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2012 (fr) наукова стаття, опублікована в січні 2013 (uk) im Januar 2013 veröffentlichter wissenschaftlicher Artikel (de) scientific article published on 16 November 2012 (en) artículu científicu espublizáu en payares de 2012 (ast)
publication date	wds:Q56964274-DEABC74B-FBFC-447C-97C0-8D67081877DA
publication date	2012-11-16 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q56964274-84D55DF6-2BB5-4005-AD92-8FF644721600
language of work or name	English
author name string	wds:Q56964274-2BB1CEB0-CBE5-4952-8FCC-C5FC836A4020 wds:Q56964274-625FFDCD-A5DA-45C2-81F8-A17AFF4F5B7D wds:Q56964274-BB72189C-D7D2-40B4-9B2D-779714ED3F70
author name string	Peter Nightingale Petra Schneider Xavier Bertagna
rdfs:label	Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement (en) Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement (nl)
skos:prefLabel	Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement (en) Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement (nl)
name	Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement (en) Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement (nl)
author	wds:Q56964274-35A1F780-4671-4AE6-9E78-3999ADCA7B45 wds:Q56964274-3AABD072-6339-4837-A05C-57A64FC8924B wds:Q56964274-527C4BA8-B203-4DD8-83AE-2140DEA7B23B wds:Q56964274-575A9794-207D-4FD6-ADD7-E144C296E973 wds:Q56964274-5CC03409-BB07-44F3-BB22-F0EC66890E82 wds:Q56964274-5DCB1024-3C80-405C-BF36-242C52344714 wds:Q56964274-5F219F69-6B0F-4DD1-8ADD-F5BE681278A2 wds:Q56964274-6175FE31-8F7B-49FF-9D63-80FC3B9FDD09 wds:Q56964274-65B2C5A9-15DE-4430-8C2E-8E8A90A17575 wds:Q56964274-803A8919-38AD-4F7D-9630-64AE7B663957 wds:Q56964274-9760F912-591C-4376-AA1B-5A9D9D8921AC wds:Q56964274-993084F5-C1AA-4C6B-96E3-15A35CFC030C wds:Q56964274-9A4BFA51-789D-461A-AFEA-CF8AD8CE49F1 wds:Q56964274-A9C4B94D-76A7-4226-A6D4-510C385C2CC3 wds:Q56964274-AB2984B5-1B31-4D48-9D91-5B496BC27160 wds:Q56964274-ACD2B36B-A729-493E-BFF6-A271539FA77A wds:Q56964274-BBA525C7-F2E2-4860-AE1E-9284E41A931A wds:Q56964274-C847EC7A-C478-4967-B03B-40BFAA905B72 wds:Q56964274-D772C5C0-F6D2-417E-8E64-9FAF4CDAAD86 wds:Q56964274-DDCC64C0-D9BB-4E59-942F-FC897C020C37 wds:Q56964274-E1CECF2E-ADC6-4DBB-8449-98445CDBFCCA wds:Q56964274-FAE09002-FE73-4D6A-A059-416D7D20077A
author	Paul Stewart Wiebke Arlt Jérome Bertherat Felix Beuschlein Marcus Quinkler Rossella Libé Beverly A Hughes Donna M O'Neil Stefanie Hahner Vasileios Chortis Jeremy W Tomlinson Cedric H L Shackleton Massimo Terzolo Giuseppe Opocher Bruno Allolio Martin Fassnacht Massimo Mannelli Angela. E. Taylor Niki Karavitaki Franco Mantero Emilio Porfiri Mark Sherlock
title	wds:Q56964274-576D3D44-E267-4E57-BDD5-8F63BF915607
title	Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement (en)
page(s)	wds:Q56964274-A9CE391C-7725-4E2E-80F3-241E7CF49F44
page(s)	161-171
instance of	wds:Q56964274-B7CFEB27-A168-494A-AAD7-B3BC3C8513C4
instance of	scholarly article
PubMed ID	wds:Q56964274-C5D1B2C5-A0FE-4EFE-B4C9-34278A436BEC
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/23162091
PubMed ID	23162091
published in	wds:Q56964274-BBAEFBB9-A772-49EA-A741-EE2C83932231
published in	The Journal of Clinical Endocrinology and Metabolism
issue	wds:Q56964274-0747453D-094D-45DC-8285-733F69F78F85
volume	wds:Q56964274-E3C84454-B619-44C6-87B8-5CB122E53C24
issue	1
volume	98
DOI	wds:Q56964274-303D7824-814C-45A3-8A58-44F726DAB0C6
DOI	http://dx.doi.org/10.1210/JC.2012-2851
DOI	10.1210/JC.2012-2851
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q56964274
is cites work of	Adrenocortical carcinoma Diagnosis, treatment and outcome of adrenocortical cancer Developing treatment for adrenocortical carcinoma Rapid and Complete Remission of Metastatic Adrenocortical Carcinoma Persisting 10 Years After Treatment With Mitotane Monotherapy: Case Report and Review of the Literature Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline The lack of antitumor effects of o,p'DDA excludes its role as an active metabolite of mitotane for adrenocortical carcinoma treatment Salvage Treatment of Adrenocortical Carcinoma with Trofosfamide Diagnosis and management of adrenal insufficiency Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline Management of adrenal cancer: a 2013 update Adrenocortical carcinoma: the management of metastatic disease Outcomes after resection of cortisol-secreting adrenocortical carcinoma Current management options for recurrent adrenocortical carcinoma P450 Enzymes in Steroid Processing

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