About: mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor

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About: mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor Goto Sponge NotDistinct Permalink

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scientific article published in Journal of Biological Chemistry

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 1996 (uk) article publié dans la revue scientifique Journal of Biological Chemistry (fr) im August 1996 veröffentlichter wissenschaftlicher Artikel (de) scientific article published in Journal of Biological Chemistry (en)
publication date	wds:Q56871535-0D0BA8D6-993E-4F59-8ADA-92F0B590801E
publication date	1996-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q56871535-B1215B38-10C6-4977-A58B-0B8F00B97B69
language of work or name	English
cites work	wds:Q56871535-010457EB-CAFE-462D-A6A5-BC12C8BE65A3 wds:Q56871535-0759052A-0048-4A71-A0A8-A2C0FBB4D917 wds:Q56871535-1D0CCB19-E539-4360-971A-0C04E6547187 wds:Q56871535-2659393D-BB8A-450F-869F-E45606883FAE wds:Q56871535-3826169F-48AD-4688-AC1A-7E6D07F6AC29 wds:Q56871535-46700C47-E911-433C-8BFE-62C0887B0829 wds:Q56871535-518B5E7B-0BAE-494B-9412-F71BC7DBFCBB wds:Q56871535-56BC86AF-FAE7-4692-887E-FEAAFFEAC3EB wds:Q56871535-60F48032-CCCB-4FCF-8BE4-FC86632872C9 wds:Q56871535-68754D4D-D3E8-49FC-940C-89E8608421AD wds:Q56871535-7508FDF4-1ADD-4125-B3FA-9F345A9F6EDC wds:Q56871535-7D823C2B-31DD-468F-BBF3-C78FCCF06550 wds:Q56871535-7E20C528-EAC8-45B7-AC6F-ACBF0DC50F3C wds:Q56871535-83879BF2-B32F-4B33-8927-82E3163DD7F9 wds:Q56871535-A811789E-A3CF-416C-AFB0-413D99AD818D wds:Q56871535-BCD84F90-F9FB-45EE-9E27-77DF8C96EB3B wds:Q56871535-D07E34C6-BDE0-46D0-AAB5-4D5666ABE963 wds:Q56871535-D5BF5970-A265-4F94-BA13-1910B641670F wds:Q56871535-D5F8C9D9-A1CD-4E40-A56E-904C8D2B61D6 wds:Q56871535-D9297C5B-2E96-4522-95A3-1D86E24CB2DC wds:Q56871535-DDDAAB8F-929D-4587-9C51-C810267EF268 wds:Q56871535-E1FF470E-C0D2-4588-8A38-BDB8D685F303 wds:Q56871535-E6072917-E301-46CF-A7FE-258DC8EF48C5 wds:Q56871535-E7004F99-62C4-414A-8C3E-D4013018541A wds:Q56871535-F32796A7-6BC8-4698-90EA-C483E80100A1 wds:Q56871535-FAD99A02-B0DE-47A9-BE83-38578A90472B
cites work	Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. A transplantable insulinoma in the rat Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas Expression of a single transfected cDNA converts fibroblasts to myoblasts Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cells Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor Comparison of cytokine effects on mouse pancreatic alpha-cell and beta-cell lines. Viability, secretory function, and MHC antigen expression Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene Insulin-promoter-factor 1 is required for pancreas development in mice Novel insulin promoter- and enhancer-binding proteins that discriminate between pancreatic alpha- and beta-cells Pancreatic beta cells express a diverse set of homeobox genes Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Cloned cell lines from a transplantable islet cell tumor are heterogeneous and express cholecystokinin in addition to islet hormones Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons. Peptide contents of neuropeptide Y, vasoactive intestinal polypeptide, and beta-calcitonin gene-related peptide and their messenger ribonucleic acids after dexamethasone treatment in the isolated rat islets of Langerhans Tissue-specific expression of transfected human insulin genes in pluripotent clonal rat insulinoma lines induced during passage in vivo Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells The physiology of calcitonin gene-related peptide in the islet compared with that of islet amyloid polypeptide (amylin). Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells Islet Amyloid Polypeptide and Insulin Expression Are Controlled Differently in Primary and Transformed Islet Cells The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site. Pattern of thyrotropin-releasing hormone secretion from the adult and neonatal rat pancreas: comparison with insulin secretion
author name string	wds:Q56871535-1D353259-8246-4903-950B-FBE0EC65C112 wds:Q56871535-35239C81-5419-4B68-B5BF-52D6AE564DDA wds:Q56871535-478DEEBF-8423-4D86-B315-F279483A1658 wds:Q56871535-511B00B9-80EE-4A2D-A87A-FC4F87A62F27
author name string	O D Madsen T F Nielsen P Serup C Karlsen
rdfs:label	mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor (en) mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor (nl)
skos:prefLabel	mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor (en) mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor (nl)
name	mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor (en) mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor (nl)
author	wds:Q56871535-04A0E0F0-58E0-40B8-A434-ABC1D3A78BAD
author	Jan Jensen
title	wds:Q56871535-B9BBF3AE-140E-4950-84CE-69DE272FB313
title	mRNA profiling of rat islet tumors reveals nkx 6.1 as a beta-cell-specific homeodomain transcription factor (en)
page(s)	wds:Q56871535-0DAA780D-7A04-4713-B72F-E8F89E2ABA90
page(s)	18749-18758
instance of	wds:Q56871535-C56FC857-0047-4F30-8C8C-C1385F48E712
instance of	scholarly article
PubMed ID	wds:Q56871535-FE685DA0-CA02-41C7-AECA-A625A0E83171
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8702531
PubMed ID	8702531
published in	wds:Q56871535-9FBF1F9D-3F5F-40D9-ADBF-BC1EB416CC92
published in	Journal of Biological Chemistry
issue	wds:Q56871535-8C38497A-BBF8-44ED-B353-3EBC1E44E108
volume	wds:Q56871535-A73DD6DD-82BD-4810-9DB2-759BF1B74855
issue	31
volume	271
DOI	wds:Q56871535-EEE7A987-D612-4063-A00C-8EAF6AACD645
DOI	http://dx.doi.org/10.1074/JBC.271.31.18749
DOI	10.1074/JBC.271.31.18749
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q56871535
is cites work of	Ca2+/calmodulin-dependent protein kinase II delta2 regulates gene expression of insulin in INS-1 rat insulinoma cells. Developmental biology of the Psammomys obesus pancreas: cloning and expression of the Neurogenin-3 gene

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