About: A p53-dependent mouse spindle checkpoint

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scientific article published in Science

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 1995 (uk) article publié dans la revue scientifique Science (fr) im März 1995 veröffentlichter wissenschaftlicher Artikel (de) scientific article published in Science (en)
publication date	wds:Q56445949-091BFF7B-AA86-4587-ADDB-278EF15D8159
publication date	1995-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q56445949-B1586492-C383-4505-A869-AF41F8A430BB
language of work or name	English
author name string	wds:Q56445949-3A66AE09-B09B-4AF3-B154-58B07522A628 wds:Q56445949-724C7EB7-5EED-40DC-AEFF-83B53528D2AC wds:Q56445949-75078335-F1C8-474D-B1EC-9EA82BC1C40F wds:Q56445949-782B400F-D1C7-4138-BA8E-18B85BBE24CE wds:Q56445949-855E1E27-356E-4300-932D-15EF953A45AD wds:Q56445949-85AD3F60-617E-401B-8609-2B190E35D645 wds:Q56445949-9B8DBF96-649A-40C0-88D6-6F214A023A31 wds:Q56445949-D2C74A60-1EE9-4639-B416-73D6F553FE3A
author name string	R L Idzerda B J Reid C A Sanchez S Ramel W H Raskind C A Morgan S M Cross M K Schimke
rdfs:label	A p53-dependent mouse spindle checkpoint (en) A p53-dependent mouse spindle checkpoint (nl)
skos:prefLabel	A p53-dependent mouse spindle checkpoint (en) A p53-dependent mouse spindle checkpoint (nl)
name	A p53-dependent mouse spindle checkpoint (en) A p53-dependent mouse spindle checkpoint (nl)
title	wds:Q56445949-0CFD0312-811C-4A72-99CD-8E724CE91308
title	A p53-dependent mouse spindle checkpoint (en)
page(s)	wds:Q56445949-6982B194-4186-44B1-BD08-EFC61638898F
page(s)	1353-1356
instance of	wds:Q56445949-978D1066-55EB-42F4-A5BC-7D0D26CA628A
instance of	scholarly article
PubMed ID	wds:Q56445949-4F449561-008C-4431-BD2A-60E18930E468
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7871434
PubMed ID	7871434
published in	wds:Q56445949-23A79DE4-2D92-4118-8568-065B94AD7B66
published in	Science
issue	wds:Q56445949-0852F9E9-F1CC-4909-9EA9-B760480660C6
volume	wds:Q56445949-1E0BC63D-F430-452E-9D07-D89184E5BC1E
issue	5202
volume	267
DOI	wds:Q56445949-D44F7380-09B9-4908-8736-3530C48D81B5
DOI	http://dx.doi.org/10.1126/SCIENCE.7871434
DOI	10.1126/SCIENCE.7871434
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q56445949
is cites work of	The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase Insights into cancer from transgenic mouse models 17p (p53) allelic losses, 4N (G2/tetraploid) populations, and progression to aneuploidy in Barrett's esophagus Predictors of progression in Barrett's esophagus III: baseline flow cytometric variables The murine C'-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1. Hypothesis: "Rogue cell"-type chromosomal damage in lymphocytes is associated with infection with the JC human polyoma virus and has implications for oncopenesis The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity Tumor-derived p53 mutant C174Y is a gain-of-function mutant which activates the fos promoter and enhances colony formation Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression Human cytomegalovirus infection inhibits G1/S transition. p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells Identification of a novel transcriptional regulatory element common to the p53 and interferon regulatory factor 1 genes Mechanisms of Photoaging and Cutaneous Photocarcinogenesis, and Photoprotective Strategies with Phytochemicals The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis DNA adducts and chronic degenerative disease. Pathogenetic relevance and implications in preventive medicine. The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression Distinctive patterns of Her-2/neu, c-myc, and cyclin D1 gene amplification by fluorescence in situ hybridization in primary human breast cancers Growth retardation, polyploidy, and multinucleation induced by Clast3, a novel cell cycle-regulated protein Control of mouse hepatocyte proliferation and ploidy by p53 and p53ser246 mutation in vivo Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA. Requirement of wild-type p53 protein for maintenance of chromosomal integrity Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2. p53 is associated with cellular microtubules and is transported to the nucleus by dynein Checking out the G(2)/M transition. p53: traffic cop at the crossroads of DNA repair and recombination The p53 network in lung carcinogenesis. Construction by gene targeting in human cells of a "conditional' CDC2 mutant that rereplicates its DNA. Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis Twenty years of p53 research: structural and functional aspects of the p53 protein Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain Multisite phosphorylation and the integration of stress signals at p53. BRCA1 protein products ... Functional motifs... Vanadate-Induced Cell Growth Arrest is p53-dependent through Activation of p21 in C141 Cells Cell cycle control, checkpoint mechanisms, and genotoxic stress Hyperproliferation and p53 status of lens epithelial cells derived from alphaB-crystallin knockout mice Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation Identification and classification of p53-regulated genes Genetic instabilities in human cancers Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage The p53 network

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