About: Lucy Walker

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An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

researcher (ORCID 0000-0001-5986-5015)

Attributes	Values
rdf:type	Item
description	forskare (sv) ikertzailea (eu) 연구원 (ko) গবেষক (bn) 研究者 (ja) araştırmacı (tr) эрдэмтэн (mn) वैज्ञानिक (hi) 研究者 (zh) հետազոտող (hy) onderzoeker (nl) hulumtuese (sq) researcher (ORCID 0000-0001-5986-5015) (en)
rdfs:label	Lucy Walker (en) Lucy Walker (es) Lucy Walker (nl) Lucy Walker (sl) Lucy Walker (ast) Люси Уокер (ru) لوسي ووكر (ar) Lucy S.K. Walker (de)
skos:prefLabel	Lucy Walker (en) Lucy Walker (es) Lucy Walker (nl) Lucy Walker (sl) Lucy Walker (ast) Люси Уокер (ru) لوسي ووكر (ar) Lucy S.K. Walker (de)
name	Lucy Walker (en) Lucy Walker (es) Lucy Walker (nl) Lucy Walker (sl) Lucy Walker (ast) Люси Уокер (ru) لوسي ووكر (ar) Lucy S.K. Walker (de)
floruit	wds:Q42812602-675EF97B-8A1A-4FD9-A3B6-6C9A7429FB22
floruit	1994-01-01 00:00:00Z (xsd:dateTime)
given name	wds:Q42812602-3619013E-CF29-4126-B3E7-6E729560E5AA
given name	Lucy
instance of	wds:Q42812602-25EE6D9E-D7A2-46C5-82E8-2DAB4BD05FC4
instance of	Homo sapiens
Loop ID	wds:Q42812602-C71A3117-EF38-4115-979F-DB5BBAC2FD8A
Loop ID	497194
skos:altLabel	Lucy S.K. Walker (en) Lucy S.K. Walker (es) Lucy S.K. Walker (nl) Lucy S.K. Walker (ast)
occupation	wds:Q42812602-40F6B1A0-1901-42AC-A8E6-0109D7853E02
employer	wds:Q42812602-813A4687-0A5C-4A9F-B40E-5DB9E9A4E6A1 wds:Q42812602-9C771E7D-BDC8-46A8-AC96-0C0C04529DD4 wds:Q42812602-CBA97106-2B6B-445A-A7FB-43A1945539F7 wds:Q42812602-D90A9DDC-778F-42BE-8FDA-351986A94595 wds:Q42812602-DA6FD796-B0D1-4B1E-A466-391A4D57FF26
sex or gender	wds:Q42812602-AB1CA9E5-6C89-4E12-B405-8B6F054C53F5
educated at	wds:Q42812602-2A47AD8C-E523-4C9E-9A67-FCCD4E3AB2B9
family name	wds:Q42812602-1387F083-2462-436B-9FEB-C3B7D23F9345
official website	wds:Q42812602-7E8F8AC1-55A3-40F2-B0B4-7A1E35E45DAD
occupation	researcher
employer	University College London University of California, San Francisco University of Birmingham
sex or gender	female organism
educated at	University of Bath
family name	Walker
official website	http://iris.ucl.ac.uk/iris/browse/profile?upi=LWALK65
ORCID iD	wds:Q42812602-49FBC788-8BF8-4276-BE07-F56CA04235D7
ORCID iD	https://orcid.org/0000-0001-5986-5015
ORCID iD	0000-0001-5986-5015
AcademiaNet ID	wds:Q42812602-EF42AB43-DD29-4343-B84E-85ABC2B0CBF0
AcademiaNet ID	1363087
is owl:sameAs of	Lucy Walker
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q42812602
is author of	The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology Follicular helper T cell signature in type 1 diabetes CD4 T cell differentiation in type 1 diabetes. Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21. Treg and CTLA-4: two intertwining pathways to immune tolerance Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers. Confusing signals: recent progress in CTLA-4 biology 1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3. Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells. Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleen IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. CD4 + CD25 + Cells Controlling a Pathogenic CD4 Response Inhibit Cytokine Differentiation, CXCR-3 Expression, and Tissue Invasion Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3 IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis. CTLA4 gene polymorphism and autoimmunity Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95 IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease Regulatory T cells overturned: the effectors fight back Established T cell-driven germinal center B cell proliferation is independent of CD28 signaling but is tightly regulated through CTLA-4.

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