About: Kevin A. Roth

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Chair of the Department of Pathology and Cell Biology at Columbia University Medical Center

Attributes	Values
rdf:type	Item
description	wetenschapper (nl) дослідник (uk) հետազոտող (hy) Chair of the Department of Pathology and Cell Biology at Columbia University Medical Center (en)
rdfs:label	Kevin A. Roth (en) Kevin A. Roth (es) Kevin A. Roth (nl) Kevin A. Roth (sl) Kevin A. Roth (ast)
skos:prefLabel	Kevin A. Roth (en) Kevin A. Roth (es) Kevin A. Roth (nl) Kevin A. Roth (sl) Kevin A. Roth (ast)
name	Kevin A. Roth (en) Kevin A. Roth (es) Kevin A. Roth (nl) Kevin A. Roth (sl) Kevin A. Roth (ast)
Scopus author ID	wds:Q42407889-ab81925d-4376-04b7-0c79-abb232b175af
Scopus author ID	57200693799
given name	wds:Q42407889-F8DBD432-887A-4686-9D55-70049CC68340
given name	Kevin
instance of	wds:Q42407889-AB9086F6-CDF0-4F2F-B7F9-76A7A65CFDF1
instance of	Homo sapiens
skos:altLabel	Kevin Roth (en)
occupation	wds:Q42407889-62E30D02-759E-4011-8D57-4FDE638E4100
employer	wds:Q42407889-0d006b8a-4da1-88e9-d358-65680db4f210
sex or gender	wds:Q42407889-BFFD063B-71DE-4D77-A993-4230F7903E15
family name	wds:Q42407889-7F452C33-4663-4508-BD96-0BA4A55294F5
occupation	pathologist
employer	Columbia University
sex or gender	male
family name	Roth
ORCID iD	wds:Q42407889-A8CF221E-CB7C-46C6-9055-AC52FF0A272A
ORCID iD	https://orcid.org/0000-0002-0643-995X
ORCID iD	0000-0002-0643-995X
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q42407889
is author of	Rnx deficiency results in congenital central hypoventilation Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis. Kainic acid induces early and transient autophagic stress in mouse hippocampus Tissue transglutaminase overexpression in the brain potentiates calcium-induced hippocampal damage. Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14 Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease. Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125. Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney Regulated targeting of BAX to mitochondria. Spatial differentiation of the intestinal epithelium: analysis of enteroendocrine cells containing immunoreactive serotonin, secretin, and substance P in normal and transgenic mice Immunohistochemical studies indicate multiple enteroendocrine cell differentiation pathways in the mouse proximal small intestine Science isn't science if it isn't reproducible Localization of electrogenic Na/bicarbonate cotransporter NBCe1 variants in rat brain Identification of gastrin releasing peptide-related substances in guinea pig and rat brain. Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent Ethanol-induced caspase-3 activation in the in vivo developing mouse brain Regulation of mouse brain glycogen synthase kinase-3 by atypical antipsychotics. The proapoptotic BH3-only, Bcl-2 family member, Puma is critical for acute ethanol-induced neuronal apoptosis Pancreastatin distribution and plasma levels in the pig. BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death. The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy. CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress Aging and energetics' 'Top 40' future research opportunities 2010-2013. Labeled lines in the retinotectal system: markers for retinorecipient sublaminae and the retinal ganglion cell subsets that innervate them Neural precursor cells are protected from apoptosis induced by trophic factor withdrawal or genotoxic stress by inhibitors of glycogen synthase kinase 3. Apaf1-dependent programmed cell death is required for inner ear morphogenesis and growth. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death Acromegaly and pheochromocytoma: a multiple endocrine syndrome caused by a plurihormonal adrenal medullary tumor. Stress, behavioral arousal, and open field activity--a reexamination of emotionality in the rat. Acute and chronic stress effects on open field activity in the rat: implications for a model of depression Distribution of gastrin releasing peptide--bombesin-like immunostaining in rat brain. Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. Bcl-2 family regulation of neuronal development and neurodegeneration. Cholera toxin binds to differentiating neurons in the developing murine basal ganglia A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death Rotenone inhibits autophagic flux prior to inducing cell death. Isolation and characterization of substance P, substance P 5-11, and substance K from two metastatic ileal carcinoids. Selective involvement of BH3-only Bcl-2 family members Bim and Bad in neonatal hypoxia-ischemia. N-terminally deleted forms of the prion protein activate both Bax-dependent and Bax-independent neurotoxic pathways. Bcl-2 family and the central nervous system: from rheostat to real complex. Intracranial ependymoma long term outcome, patterns of failure. Acute neonatal glucocorticoid exposure produces selective and rapid cerebellar neural progenitor cell apoptotic death Role of caspase-3 in ethanol-induced developmental neurodegeneration Apoptosis and brain development. Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation. Lysosome dysfunction triggers Atg7-dependent neural apoptosis bcl-2/Adenovirus E1B 19-kd interacting protein 3 (BNIP3) regulates hypoxia-induced neural precursor cell death Colocalization of alpha-neo-endorphin and dynorphin immunoreactivity in hypothalamic neurons. Methionine-enkephalin and thyrotropin-stimulating hormone are intimately related in the human anterior pituitary. Immunoreactive dynorphin-(1-8) and corticotropin- releasing factor in subpopulation of hypothalamic neurons Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain Immunohistochemical localization of GAP-43 in rat and human sympathetic nervous system--effects of aging and diabetes Neural precursor cells possess multiple p53-dependent apoptotic pathways. Blockade of glutamate mGlu5 receptors in a rat model of neuropathic pain prevents early over-expression of pro-apoptotic genes and morphological changes in dorsal horn lamina II. Protector turns predator: Autophagic death via selective degradation of KRAS. Appetitive determinants of self-stimulation. Loss of BH3-only protein Bim inhibits apoptosis of hemopoietic cells in the fetal liver and male germ cells but not neuronal cells in bcl-x-deficient mice p53 deficiency fails to prevent increased programmed cell death in the Bcl-X(L)-deficient nervous system

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