About: Natural variation at position 45 in the D1 domain of lineage III killer cell immunoglobulin-like receptors (KIR) has major effects on the avidity and specificity for MHC class I

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About: Natural variation at position 45 in the D1 domain of lineage III killer cell immunoglobulin-like receptors (KIR) has major effects on the avidity and specificity for MHC class I Goto Sponge NotDistinct Permalink

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scientific article published on 04 May 2011

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description	videnskabelig artikel (da) article científic (ca) articol științific (ro) articolo scientifico (it) artigo científico (gl) artigo científico (pt) artigo científico (pt-br) artikull shkencor (sq) artículo científico (es) bilimsel makale (tr) scienca artikolo (eo) vedecký článok (sk) vetenskaplig artikel (sv) vitenskapelig artikkel (nb) vitskapeleg artikkel (nn) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научная статья (ru) научни чланак (sr) מאמר מדעי (he) artikel ilmiah (id) article scientifique (fr) বৈজ্ঞানিক নিবন্ধ (bn) наукова стаття, опублікована в травні 2011 (uk) artículu científicu espublizáu en 2011 (ast) 2011 nî lūn-bûn (nan) 2011年の論文 (ja) 2011年論文 (zh-hk) 2011年論文 (zh-tw) 2011年論文 (zh-hant) 2011年論文 (yue) 2011年論文 (zh-mo) 2011年论文 (zh) 2011年论文 (zh-cn) 2011年论文 (zh-sg) 2011年论文 (zh-hans) 2011年论文 (wuu) 2011年论文 (zh-my) 2011년 논문 (ko) scientific article published on 04 May 2011 (en) scientific article published on 04 May 2011 (en-ca) scientific article published on 04 May 2011 (en-gb) مقالة علمية نشرت في 04 مايو 2011 (ar)
publication date	wds:Q38257426-54926411-25F8-4F27-976D-95392A1EB81A
publication date	2011-05-04 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q38257426-D18306B1-13A3-47A3-9524-4466F39BD15D
language of work or name	English
exact match	wds:Q38257426-CEA4A58B-F5DF-48C5-A0A7-95B932DAA52A
exact match	https://scigraph.springernature.com/pub.10.1007/s00251-011-0527-7
cites work	wds:Q38257426-00C6D926-08A2-473E-AA4F-E1A129F8EC71 wds:Q38257426-02848B83-BD7F-47BB-B483-F28BA4AC8C50 wds:Q38257426-0451F154-2B53-4F1B-AD67-3AC18DFFDA6D wds:Q38257426-08B8FBB9-CA88-4BBA-B312-A1C5BADE6A38 wds:Q38257426-09F82043-3803-4329-9185-A0A5B2BE6053 wds:Q38257426-0C752796-8C8F-452F-9339-15DC796A895E wds:Q38257426-0F7E98C1-54F3-4099-B6DE-B7CBFCA33139 wds:Q38257426-1F653F91-026B-4810-8AE8-16F5EDCC85D6 wds:Q38257426-3DA86DD6-BCDC-4146-9130-583019B26AB1 wds:Q38257426-4AF2B742-3FF0-4071-8244-6F6017F40B4E wds:Q38257426-510142D8-B521-4B09-BBAC-94C11E4BD0D7 wds:Q38257426-5F6B1841-AC4A-455C-B362-EC848A3C738E wds:Q38257426-64A9AAE6-546D-4BF8-8A4E-2CB8847FD4F6 wds:Q38257426-9698B97D-2CFA-419C-A04D-35FA1BB59019 wds:Q38257426-A14EAAA5-5C59-4B23-96EC-16F515EB4BCA wds:Q38257426-C18D5461-8780-4033-846E-ABF5C33EF3E0 wds:Q38257426-C8F9A08E-88DE-4FA1-9360-DFE569559CC8 wds:Q38257426-CAC49A16-AC2D-4064-A41A-769CB0E923EF wds:Q38257426-DDE91141-9CDE-434B-8F44-B33993148C1A wds:Q38257426-ECFCBAB1-DAC5-4B13-AE02-5FC3D6AFACAC wds:Q38257426-F5F74BF8-F199-4F72-A38A-4BB4A752AD7E
cites work	Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules. Crystal Structure of the Human Natural Killer Cell Activating Receptor KIR2DS2 (CD158j) MHC class I molecules and KIRs in human history, health and survival Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 epitope of MHC class I Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition. NK cell receptors of the orangutan (Pongo pygmaeus): a pivotal species for tracking the coevolution of killer cell Ig-like receptors with MHC-C. The expanded cattle KIR genes are orthologous to the conserved single-copy KIR3DX1 gene of primates MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response KIR acquisition probabilities are independent of self-HLA class I ligands and increase with cellular KIR expression. Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes A small, variable, and irregular killer cell Ig-like receptor locus accompanies the absence of MHC-C and MHC-G in gibbons Natural killer cell recognition of missing self Coevolution of killer cell Ig-like receptors with HLA-C to become the major variable regulators of human NK cells A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes Domain shuffling has been the main mechanism forming new hominoid killer cell Ig-like receptors KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A * 11 while diminishing avidity for HLA-C Surface NK receptors and their ligands on tumor cells Evidence for an HLA-C-like locus in the orangutan Pongo pygmaeus.
author name string	wds:Q38257426-01392EE9-83BB-42A6-82EA-B1CD7216ABCB wds:Q38257426-0E8E67BA-F776-4A53-839E-386DCBD1C0FB wds:Q38257426-14188C5B-18D0-4B31-8D69-AD9A9F489C32
author name string	Peter Parham Laurent Abi-Rached Anastazia M Older Aguilar
rdfs:label	Natural variation at position 45 in the D1 domain of lineage III killer cell immunoglobulin-like receptors (KIR) has major effects on the avidity and specificity for MHC class I (en)

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