About: Franklin H. Epstein Lecture: Sirtuins, aging, and medicine

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scientific article published on June 2011

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) gotara zanistî (ku-latn) наукова стаття, опублікована в червні 2011 (uk) مقالة علمية نشرت في يونيو 2011 (ar) scientific article published on June 2011 (en) artículu científicu espublizáu en xunu de 2011 (ast)
publication date	wds:Q37886170-5B4958B1-1CD2-4C97-8B1B-16567CB7304C
publication date	2011-06-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37886170-E877F200-AD50-4A32-9FE1-38899683FC4A
language of work or name	English
cites work	wds:Q37886170-2D196F08-3D1C-4997-87D0-8712F591C1AD wds:Q37886170-8F73001C-5BF2-4D8B-9D4E-0F8B10BDBF0E wds:Q37886170-DDFB7462-07D7-4F9D-BC31-B575B4965ABC
cites work	DBC1 is a negative regulator of SIRT1 Negative regulation of the deacetylase SIRT1 by DBC1 SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.
author name string	wds:Q37886170-551601A2-9E58-47DF-86B5-144919F06810
author name string	Leonard Guarente
rdfs:label	Franklin H. Epstein Lecture: Sirtuins, aging, and medicine (en) Franklin H. Epstein Lecture: Sirtuins, aging, and medicine (nl)
skos:prefLabel	Franklin H. Epstein Lecture: Sirtuins, aging, and medicine (en) Franklin H. Epstein Lecture: Sirtuins, aging, and medicine (nl)
name	Franklin H. Epstein Lecture: Sirtuins, aging, and medicine (en) Franklin H. Epstein Lecture: Sirtuins, aging, and medicine (nl)
title	wds:Q37886170-E41568B5-629E-42F5-BFEB-61F6B6EB1F93
title	Franklin H. Epstein Lecture: Sirtuins, aging, and medicine (en)
page(s)	wds:Q37886170-79C16A0D-25D2-4A33-8CC5-6B24C0C5D400
page(s)	2235-2244
instance of	wds:Q37886170-40ff76ed-089b-449e-9fea-f042573f68e3 wds:Q37886170-DAC3CD4A-B352-4536-AFF6-1DCA29724A20
instance of	review article scholarly article
PubMed ID	wds:Q37886170-C93B73B4-5A80-4EC7-AB4D-86A4D29EE9DF
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21651395
PubMed ID	21651395
published in	wds:Q37886170-83076530-2967-4681-AC88-E0593F3C39EF
published in	The New England Journal of Medicine
issue	wds:Q37886170-6060C3A8-D669-4B4C-B003-41FB14EAC415
volume	wds:Q37886170-F8F1A99F-86A3-444E-A9A7-266651230399
issue	23
volume	364
DOI	wds:Q37886170-DD47E367-969A-42FC-93B4-6E16C0449B8B
DOI	http://dx.doi.org/10.1056/NEJMRA1100831
DOI	10.1056/NEJMRA1100831
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q37886170
is cites work of	Hypothalamic inflammation: a double-edged sword to nutritional diseases Influence of metabolism on epigenetics and disease Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene Sirtuin 1 and aging theory for chronic obstructive pulmonary disease Protective effects of sirtuins in cardiovascular diseases: from bench to bedside Adrenergic signaling and oxidative stress: a role for sirtuins? Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process Synthesis and evaluation of substituted chroman-4-one and chromone derivatives as sirtuin 2-selective inhibitors Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress The multifaceted functions of sirtuins in cancer Circadian transcriptome analysis in human fibroblasts from Hunter syndrome and impact of iduronate-2-sulfatase treatment SIRT1-related inhibition of pro-inflammatory responses and oxidative stress are involved in the mechanism of nonspecific low back pain relief after exercise through modulation of Toll-like receptor 4. Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol Resveratrol attenuates renal injury and fibrosis by inhibiting transforming growth factor-β pathway on matrix metalloproteinase 7. The roles of senescence and telomere shortening in cardiovascular disease SIRT1 suppresses the epithelial-to-mesenchymal transition in cancer metastasis and organ fibrosis Redox Signaling in Diabetic Nephropathy: Hypertrophy versus Death Choices in Mesangial Cells and Podocytes Ageing: longevity hits a roadblock Role of forkhead transcription factors in diabetes-induced oxidative stress Are sirtuins viable targets for improving healthspan and lifespan? Sirtuins as regulators of metabolism and healthspan Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice. Regulation of sirtuin function by posttranslational modifications Sirtuins: from metabolic regulation to brain aging The tangled circuitry of metabolism and apoptosis Sirtuins mediate mammalian metabolic responses to nutrient availability Sirtuins as novel players in the pathogenesis of diabetes mellitus Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease Structural basis for allosteric stimulation of Sir2 activity by Sir4 binding Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1. Ketone esters increase brown fat in mice and overcome insulin resistance in other tissues in the rat Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway Protection of the heart against ischemia/reperfusion by silent information regulator 1. SIRT1 silencing confers neuroprotection through IGF-1 pathway activation Mitochondrial biogenesis through activation of nuclear signaling proteins Mitochondrial and skeletal muscle health with advancing age Cellular metabolism and disease: what do metabolic outliers teach us? Role of nutrient-sensing signals in the pathogenesis of diabetic nephropathy Renal protective effects of resveratrol Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA. Emerging beneficial roles of sirtuins in heart failure. SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.

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