About: Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer

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About: Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer Goto Sponge NotDistinct Permalink

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scientific article published on 28 April 2010

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2010 (ast) наукова стаття, опублікована у квітні 2010 (uk) مقالة علمية نشرت في 28 أبريل 2010 (ar) scientific article published on 28 April 2010 (en)
publication date	wds:Q37760267-4F1F5C20-BB2F-4BA7-BF14-BE7B94DF65AE
publication date	2010-04-28 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37760267-AE8FF7A1-1D60-4B85-9ECF-45528D104A5A
language of work or name	English
cites work	wds:Q37760267-667F4999-B2EF-4EAB-9993-9FEE726BD8E0 wds:Q37760267-9B530744-B8F9-4913-A888-1779D9C8D051
cites work	Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily 5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue
author name string	wds:Q37760267-1BD02FD9-62E6-412B-8493-DD861AA33772 wds:Q37760267-29E0F3EB-528F-48C6-B6B1-F4B1572DF587
author name string	B Samuelsson O Rådmark
rdfs:label	Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (en) Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (nl) Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (ast)
skos:prefLabel	Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (en) Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (nl) Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (ast)
name	Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (en) Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (nl) Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (ast)
title	wds:Q37760267-D3A4CCAA-9416-4251-9CD7-1182C481455A
title	Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer (en)
page(s)	wds:Q37760267-887DD5B0-3C72-49AE-B729-92BD6C382846
page(s)	5-14
instance of	wds:Q37760267-7b680ddd-0cea-4c91-95ae-9809db2b8c7c wds:Q37760267-C9BCF0F5-5883-4489-8715-F4ED070EB169
instance of	review article scholarly article
main subject	wds:Q37760267-339119B7-FA66-496C-8209-85DC92159F0E
main subject	prostaglandin E2
PubMed ID	wds:Q37760267-D9BEC6E7-97C3-4C3A-A117-397148493627
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20497297
PubMed ID	20497297
published in	wds:Q37760267-3841A448-D474-436D-B1AB-44CF98B9A1F9
published in	Journal of Internal Medicine
issue	wds:Q37760267-3A137455-BDC9-4D71-89FE-110C5207F5B4
volume	wds:Q37760267-1D23C2F1-775B-4D02-BCEE-C3D3214A6B78
issue	1
volume	268
DOI	wds:Q37760267-F8C05F06-0636-4D1D-B6E2-4BBD70141F88
DOI	http://dx.doi.org/10.1111/J.1365-2796.2010.02246.X
DOI	10.1111/J.1365-2796.2010.02246.X
ResearchGate publication ID	wds:Q37760267-660984E3-1E98-41C3-8C6B-8092F66F994A
ResearchGate publication ID	44625368
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q37760267
is cites work of	Identification and development of mPGES-1 inhibitors: where we are at? Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorum Discovery of depsides and depsidones from lichen as potent inhibitors of microsomal prostaglandin E2 synthase-1 using pharmacophore models Prostaglandin E2 and T cells: friends or foes? Crystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamily Discovery of novel, non-acidic mPGES-1 inhibitors by virtual screening with a multistep protocol Pharmacological inhibition of microsomal prostaglandin E synthase-1 suppresses epidermal growth factor receptor-mediated tumor growth and angiogenesis Polyunsaturated fatty acid metabolism in prostate cancer Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity Cardiovascular biology of microsomal prostaglandin E synthase-1. Role of COX-2/mPGES-1/prostaglandin E2 cascade in kidney injury Molecular pharmacological profile of a novel thiazolinone-based direct and selective 5-lipoxygenase inhibitor Sex differences in prostaglandin biosynthesis in neutrophils during acute inflammation Non-steroid anti-inflammatory drugs, prostaglandins, and cancer Tetra- and pentacyclic triterpene acids from the ancient anti-inflammatory remedy frankincense as inhibitors of microsomal prostaglandin E(2) synthase-1 Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1. CRISPR/Cas9-based liver-derived reporter cells for screening of mPGES-1 inhibitors Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors Potential Antifungal Targets against a Candida Biofilm Based on an Enzyme in the Arachidonic Acid Cascade-A Review Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs.
is cites work of	wds:Q35667896-84360AB3-27F6-4C69-80A2-F6BCF8B93C90 wds:Q24629893-1043D83C-2BA4-4C6A-8DE4-B8C5D67E1B79 wds:Q41774015-B236E07D-845A-4131-98A4-A3CBDF5EDC09 wds:Q64080713-58AF56DA-3A17-40C3-904E-A71182FCD776 wds:Q89543340-69753952-E7A3-41AF-9045-CF20AFDBA659 wds:Q35097808-36C1C3B3-2561-4523-9AC1-122BC0D93B14 wds:Q28481397-8A1629F4-F7A5-45BD-BA47-8366DA9BD308 wds:Q35607129-2A657CAA-561A-48B0-9BB4-77DF56638580 wds:Q36472921-8A7A4D73-7335-4FAD-A006-3433B48D05A8 wds:Q55380925-7CA0E178-9A2B-4C78-9F96-B3DE488DDD75 wds:Q27676541-963C8588-83E1-482B-960C-C2682EBD1187 wds:Q27021151-EF1A02F7-BF91-496A-B7E6-32F428CC7640 wds:Q33812699-A731D5AB-D380-4D8B-977F-56E3315BDCBB wds:Q35150989-DFD0B528-C9B9-4109-8020-A0CCCBAD197A wds:Q34056458-205DD832-DC2D-41F5-AA85-FF981A69C226

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