About: Integrase inhibitors: a novel class of antiretroviral agents

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scientific article published on 29 December 2009

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2009 (ast) наукова стаття, опублікована в грудні 2009 (uk) scientific article published on 29 December 2009 (en) مقالة علمية نشرت في 29 ديسمبر 2009 (ar)
publication date	wds:Q37664335-3089EF94-51DF-47AB-B208-112CEEB4BE5D
publication date	2009-12-29 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37664335-972BC979-58AB-49A5-8E8B-3AC89BDDB6C9
language of work or name	English
cites work	wds:Q37664335-1C35F05D-E5B1-4E26-BBDE-83CE345FE374 wds:Q37664335-202B5EFB-BFA8-486B-B449-4FAB82FA7B14 wds:Q37664335-27FDD3B9-96EB-4C90-999E-5D0893838346 wds:Q37664335-2BBAAFC7-DC6E-4BAA-BD14-D17ACFF87ED7 wds:Q37664335-2F411206-013E-4A89-8CE5-153898948079 wds:Q37664335-2F4F513A-6AF4-4AF7-BD6C-BA141D8BC27F wds:Q37664335-34969878-7AE1-404F-B77C-23A80E8EE97D wds:Q37664335-35DF5D18-2FD7-4E2D-8813-8A1E84498C9A wds:Q37664335-3AE30FD0-BCE8-4D45-B7F2-5D087F7AD657 wds:Q37664335-4E36C480-B615-4086-B220-82DF8C9059B9 wds:Q37664335-4FE1719F-6D38-4F9A-B533-6A429CC04F06 wds:Q37664335-53BF3600-DE6E-493B-AE66-0FEF8C7CA623 wds:Q37664335-63579FFD-332B-4E21-B235-685586EE9765 wds:Q37664335-6FA8E4D0-30EF-4CF3-A52B-A15B1450B9F9 wds:Q37664335-6FBF82E8-E71A-466B-83A2-10B83DFB4669 wds:Q37664335-6FD7479D-A2D5-44E1-95E1-AFD1A5B8CFFC wds:Q37664335-72B0D900-B71C-4028-AC0E-863BA540460A wds:Q37664335-7BADB0A7-EDBC-4466-BC3A-497FF9F02C8C wds:Q37664335-7D3EC8F1-5346-4C7C-98AE-F4F8A8A5E517 wds:Q37664335-8FCA73EF-F438-4A55-8A17-53A6F1DD6783 wds:Q37664335-B20CC456-B8B2-46CD-AA9F-26FD20CF0351 wds:Q37664335-B4E8316D-298B-4BA1-BE5B-539F7D89D10B wds:Q37664335-C754C1A4-A8EB-4F98-98BA-05A90D63F2A7 wds:Q37664335-CE394619-20F5-481D-9C11-55D6BC9F86BB wds:Q37664335-D3A43BAA-7165-4BA9-9065-F7F109BB6A86 wds:Q37664335-D555D204-BB7D-43A7-AEC9-E789F4644623 wds:Q37664335-EA48FE44-B91D-413C-B09F-0F71084BA25F wds:Q37664335-F8EC2EE2-AA61-4A34-B903-84D9B4EC07F2 wds:Q37664335-F97F9F1A-04D7-49C2-A31F-01A4A3295F6E wds:Q37664335-FDE11D11-1BB9-4387-93D2-80E759B9A623
cites work	Rapid and durable antiretroviral effect of the HIV-1 Integrase inhibitor raltegravir as part of combination therapy in treatment-naive patients with HIV-1 infection: results of a 48-week controlled study Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection Integrase inhibitors to treat HIV/AIDS. Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection Decay characteristics of HIV-1-infected compartments during combination therapy Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV outpatient study. Raltegravir with optimized background therapy for resistant HIV-1 infection Determining the antiviral activity of tenofovir disoproxil fumarate in treatment-naive chronically HIV-1-infected individuals Repair of gaps in retroviral DNA integration intermediates Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial Structure and function of HIV-1 integrase Antiretroviral therapy with the integrase inhibitor raltegravir alters decay kinetics of HIV, significantly reducing the second phase Outcomes of multidrug-resistant patients switched from enfuvirtide to raltegravir within a virologically suppressive regimen Lack of a pharmacokinetic effect of raltegravir on midazolam: in vitro/in vivo correlation Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro Metabolism and disposition in humans of raltegravir (MK-0518), an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme Minimal effects of ritonavir and efavirenz on the pharmacokinetics of raltegravir Minimal pharmacokinetic interaction between the human immunodeficiency virus nonnucleoside reverse transcriptase inhibitor etravirine and the integrase inhibitor raltegravir in healthy subjects Etravirine-raltegravir, a marked interaction in HIV-1-infected patients: about four cases Effect of ritonavir-boosted tipranavir or darunavir on the steady-state pharmacokinetics of elvitegravir Pharmacokinetics of raltegravir in individuals with UGT1A1 polymorphisms Effects of omeprazole on plasma levels of raltegravir Dose-response of ritonavir on hepatic CYP3A activity and elvitegravir oral exposure Safety, tolerability, and pharmacokinetics of raltegravir after single and multiple doses in healthy subjects. Lack of a significant drug interaction between raltegravir and tenofovir. Lack of a clinically important effect of moderate hepatic insufficiency and severe renal insufficiency on raltegravir pharmacokinetics Emerging pharmacology: inhibitors of human immunodeficiency virus integration
author name string	wds:Q37664335-D8510E7C-22DB-46F6-BE0A-D593F1FEF96E wds:Q37664335-DC795522-8D4C-4D33-847C-1CD34BC1F518
author name string	Kathleen E Squires Jason J Schafer
rdfs:label	Integrase inhibitors: a novel class of antiretroviral agents (en) Integrase inhibitors: a novel class of antiretroviral agents (nl) Integrase inhibitors: a novel class of antiretroviral agents (ast)
skos:prefLabel	Integrase inhibitors: a novel class of antiretroviral agents (en) Integrase inhibitors: a novel class of antiretroviral agents (nl) Integrase inhibitors: a novel class of antiretroviral agents (ast)
name	Integrase inhibitors: a novel class of antiretroviral agents (en) Integrase inhibitors: a novel class of antiretroviral agents (nl) Integrase inhibitors: a novel class of antiretroviral agents (ast)
title	wds:Q37664335-DCF4F6D7-9C8C-4D4A-A8ED-79C269BDCAA1
title	Integrase inhibitors: a novel class of antiretroviral agents (en)
page(s)	wds:Q37664335-FF307CE7-4AB0-428B-BB5E-CF7D18F6BB7B
page(s)	145-156
instance of	wds:Q37664335-035787d9-872c-476a-b827-a9071166a231 wds:Q37664335-CA618AF9-A8C5-407A-8318-C15F7A13E412

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