About: Lori L. Isom

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An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

American pharmacologist

Attributes	Values
rdf:type	Item
owl:sameAs	Lori L. Isom
description	forskare (sv) ikertzailea (eu) 연구원 (ko) 研究者 (ja) araştırmacı (tr) wetenschapper (nl) дослідниця (uk) изилдөөчү (ky) 研究者 (zh) հետազոտող (hy) American pharmacologist (en) farmacóloga estadounidense (es) عالمة صيدلية أمريكية (ar)
exact match	wds:Q37604605-C191F77F-A1FF-4D25-AA15-CE9BC5857EF7
exact match	https://scigraph.springernature.com/person.01175550164.92
rdfs:label	Lori L Isom (fr) Lori L Isom (nl) Lori L Isom (sl) Lori L. Isom (en) Lori L. Isom (es) Lori L. Isom (it)
skos:prefLabel	Lori L Isom (fr) Lori L Isom (nl) Lori L Isom (sl) Lori L. Isom (en) Lori L. Isom (es) Lori L. Isom (it)
name	Lori L Isom (fr) Lori L Isom (nl) Lori L Isom (sl) Lori L. Isom (en) Lori L. Isom (es) Lori L. Isom (it)
Scopus author ID	wds:Q37604605-D65EBC30-155C-4177-BB2A-201211DB39FE
Scopus author ID	7003393633
given name	wds:Q37604605-9148e5b0-459f-3deb-8d1f-42ea43a39a8e
given name	Lori
instance of	wds:Q37604605-6618B151-CF94-486E-82DA-3D5DED81FE52
instance of	Homo sapiens
Academic Tree ID	wds:Q37604605-B4834389-F8B8-495F-844A-8579AA927DB7
Google Knowledge Graph ID	wds:Q37604605-80767A3F-1591-43D0-A6BE-B667C64CA71E
Google Knowledge Graph ID	http://g.co/kg/g/11h1j7qtk1
Academic Tree ID	5894
Google Knowledge Graph ID	/g/11h1j7qtk1
skos:altLabel	Lori Isom (en)
occupation	wds:Q37604605-C006D4B1-7B36-437D-B613-B41765174372
employer	wds:Q37604605-224D899F-D7A2-42B2-A233-1B7F1AA8C269 wds:Q37604605-2A971765-0E26-4C71-A550-BDD854A4531E wds:Q37604605-E8F30F58-1075-4229-982A-5F0679CCB770
place of birth	wds:Q37604605-e6043492-4633-8764-e163-7683ee76b13a
sex or gender	wds:Q37604605-A712B65E-F288-4C04-8625-8A0BB8D5EFAA
educated at	wds:Q37604605-04e12537-7ba2-452e-a374-d67f64e8dcca wds:Q37604605-c1d8aec0-f695-4881-a322-775a9baeae52 wds:Q37604605-d3889bdc-aa6d-4795-8b7f-7c373572f0c9
family name	wds:Q37604605-3D139F52-1EC4-49A8-9C77-5DD17D7E84CD
occupation	researcher
employer	University of Washington University of Michigan University of Michigan Medical School
place of birth	Oshkosh
sex or gender	female organism
educated at	Vanderbilt University University of Washington Washington University in St. Louis
family name	Isom
ORCID iD	wds:Q37604605-F3E63A4E-A1D0-47D8-88CD-69E67FFB75BD
Dimensions author ID	wds:Q37604605-BF68B05D-7F6E-4B3E-8AA1-30AB72C1C7E6
ORCID iD	https://orcid.org/0000-0002-9479-6729
ORCID iD	0000-0002-9479-6729
Dimensions author ID	01175550164.92
is owl:sameAs of	Lori L. Isom
is about of	Lori L. Isom https://www.wikidata.org/wiki/Special:EntityData/Q37604605 Lori L. Isom
is author of	Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1 Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction Auxiliary subunits of voltage-gated ion channels Modulation of cardiac Na+ channel expression in Xenopus oocytes by beta 1 subunits. Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes Early painful diabetic neuropathy is associated with differential changes in tetrodotoxin-sensitive and -resistant sodium channels in dorsal root ganglion neurons in the rat. Contactin associates with Na+ channels and increases their functional expression Tenascin-R is a functional modulator of sodium channel beta subunits Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture Molecular determinants of Na+ channel function in the extracellular domain of the beta1 subunit. Na+ channel Scn1b gene regulates dorsal root ganglion nociceptor excitability in vivo Electrophysiology and beyond: multiple roles of Na+ channel β subunits in development and disease Differential control of clustering of the sodium channels Na(v)1.2 and Na(v)1.6 at developing CNS nodes of Ranvier Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel Voltage-gated Na+ channel beta1 subunit-mediated neurite outgrowth requires Fyn kinase and contributes to postnatal CNS development in vivo Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth Therapeutic potential for phenytoin: targeting Na(v)1.5 sodium channels to reduce migration and invasion in metastatic breast cancer. Abnormal neuronal patterning occurs during early postnatal brain development of Scn1b-null mice and precedes hyperexcitability. A novel adhesion molecule in human breast cancer cells: voltage-gated Na+ channel beta1 subunit.

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