About: Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation

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About: Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation Goto Sponge NotDistinct Permalink

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description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) scholarly article (en) artículu científicu espublizáu en 2004 (ast) наукова стаття, опублікована в липні 2004 (uk) 2004年學術文章 (zh) مقالة علمية نشرت في 26 يوليو 2004 (ar)
publication date	wds:Q37512992-25EB51F2-9584-4D53-83F9-59D0C8087177
publication date	2004-07-26 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37512992-7CD3964F-6B41-4ADB-AAF3-351C1C5CC726
language of work or name	English
cites work	wds:Q37512992-0178C8C6-24D8-45F7-95EB-2E0B0BDE588A wds:Q37512992-039A10E0-C590-49DA-957A-529A3F100860 wds:Q37512992-0445C938-E181-4872-A652-60A1683A7BBB wds:Q37512992-1578F6C5-D047-4643-A9A3-C67ACD9AB22E wds:Q37512992-1EAC61F0-904E-4DC2-8BE5-8285650E502B wds:Q37512992-244FD554-3190-41D1-8566-E6434EACD73D wds:Q37512992-24D08002-08C1-48B9-AE8A-4CDD2F38151B wds:Q37512992-40948A90-94AC-424C-9A16-728F0522BC80 wds:Q37512992-50BA23F1-101B-4118-ADA9-E9129315C8A0 wds:Q37512992-526419B8-EE65-4D97-8CC7-10AA54079455 wds:Q37512992-5389A2AA-11EB-483A-B3A6-021B563A5F91 wds:Q37512992-56D090CE-FFE1-47BC-8881-F21E0947434A wds:Q37512992-5B28023B-699C-430D-A11F-39603096DB64 wds:Q37512992-601D10C4-6D96-419F-8C4B-A37B026AE6B5 wds:Q37512992-612B0C77-2EA3-48E5-9852-924AA6776593 wds:Q37512992-68C21E45-4F4B-4A3F-8F7B-C49EAAB560E4 wds:Q37512992-6C2E4541-F5DB-4028-AE1F-AD4458C00A31 wds:Q37512992-6D218F34-93D2-4C5A-AF99-A291AE7C9D21 wds:Q37512992-6E5F20EB-C659-4674-B3B9-B76E58DCED03 wds:Q37512992-7D331E11-2E02-42E4-A682-756E6152C169 wds:Q37512992-80DBBE86-D5FC-44FB-916C-AB4499E58B6F wds:Q37512992-8E3B60F3-BFCE-4777-B0E5-DDEABA2A907F wds:Q37512992-979D3CC0-A001-44A0-AF73-2F242707EDE8 wds:Q37512992-A141FA07-12EA-4662-BECB-A77997640EAE wds:Q37512992-A26386FD-62B7-4F68-848A-7A6680F9EED6 wds:Q37512992-A7E2974A-118C-4DBE-AE52-781B6F1958BC wds:Q37512992-BEE3095F-9488-45D6-83FF-4037EA96A636 wds:Q37512992-C80E85B7-5CD4-44EB-A758-8BDA6FDB9B4B wds:Q37512992-D6FECDDD-F8AC-4BD0-82FC-20BDC82FE2C2 wds:Q37512992-DB26AE65-C455-4B43-A144-319D8CB26E6E wds:Q37512992-F6379D6C-F5BC-45A9-AD29-E37E5E4F9014
cites work	Platelet glycoprotein IIb-IIIa-like proteins mediate endothelial cell attachment to adhesive proteins and the extracellular matrix. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand Integrin structure Insights into integrin-ligand binding and activation from the first crystal structure. Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation Integrins: bidirectional, allosteric signaling machines Integrin activation and structural rearrangement MOLMOL: a program for display and analysis of macromolecular structures Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA. The ligand recognition specificity of beta3 integrins Integrin structure: new twists and turns in dynamic cell adhesion A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography Crystal structure of the extracellular segment of integrin alpha Vbeta3 Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3). Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GPIIb/IIIa antibody in a canine preparation Integrin activation takes shape A Cys374Tyr homozygous mutation of platelet glycoprotein IIIa (beta 3) in a Chinese patient with Glanzmann's thrombasthenia Activation affects access to the platelet receptor for adhesive glycoproteins A comparative analysis of cDNA-derived sequences for rat and mouse beta 3 integrins (GPIIIA) with their human counterpart Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3. Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding Immobilized Arg-Gly-Asp (RGD) peptides of varying lengths as structural probes of the platelet glycoprotein IIb/IIIa receptor Studies on the binding of an alloimmune and two murine monoclonal antibodies to the platelet glycoprotein IIb-IIIa complex receptor DNA sequence of the canine platelet beta3 gene from cDNA: comparison of canine and mouse beta3 to segments that encode alloantigenic sites and functional domains of beta3 in human beings A polymorphic microsatellite located on pig chromosome band 12p11-2/3p13, within the 3'-UTR of the ITGB3 gene. Glycoprotein IIb/IIIa inhibitors: current indications and future prospects 7E3 F(ab')2, an effective antagonist of rat alphaIIbbeta3 and alphavbeta3, blocks in vivo thrombus formation and in vitro angiogenesis
author name string	wds:Q37512992-01FD9287-A189-497C-A457-7AB84D28B58E wds:Q37512992-5EA83C07-1714-42C1-A306-C4BA2A80171C wds:Q37512992-AD768F65-C749-442B-97B4-704BC99FF67F wds:Q37512992-C2238B36-1418-4085-AFDC-C1D2368E5B32 wds:Q37512992-C8C59090-12FD-4BF6-BC1F-36371C7C487F wds:Q37512992-C932D174-0424-446A-BDD5-4A69A2916699 wds:Q37512992-E4F8FE94-6E49-431B-AD50-F753F9A7DBB4
author name string	Timothy A Springer Junichi Takagi Barry S Coller Deborah L French Jian Ruan Beau Mitchell JiHong Li
rdfs:label	Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation (en) Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation (nl)

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