About: Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein

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scientific article published on 15 July 2004

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2004 (ast) наукова стаття, опублікована в липні 2004 (uk) scientific article published on 15 July 2004 (en) مقالة علمية نشرت في 15 يوليو 2004 (ar)
publication date	wds:Q37491576-CCB1DC2F-0403-49AB-B929-DF8B866E3EE6
publication date	2004-07-15 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37491576-41C2F553-492F-4665-866B-CB2EC5C8A9C2
language of work or name	English
cites work	wds:Q37491576-15A76018-AB69-422E-B8E6-019C66C66A93 wds:Q37491576-236D12E3-87ED-438A-B003-EEDAF9ADBC76 wds:Q37491576-30312201-AFBC-4BF7-99CD-740E212C75F5 wds:Q37491576-34E7D404-9BAA-40F5-B509-8E09B6BE1F1A wds:Q37491576-39678AF6-28B3-4993-844A-AC0D67C02AD2 wds:Q37491576-41318127-6D54-44BD-B1D8-B1CED816E0B7 wds:Q37491576-45D1866D-CF78-4ED6-AA31-2532A9B467CA wds:Q37491576-48DC6466-4E4C-415D-9CF2-FA22A149BA71 wds:Q37491576-5B57B42E-84A7-48F5-97B0-1C75E70377C9 wds:Q37491576-5E3821C3-D82E-4696-A280-931428A6D8D2 wds:Q37491576-5FF2C36D-888A-49D5-BDE9-5063ACE666A7 wds:Q37491576-6D4D508E-C6D4-4BE1-ACC8-CD68B53F56AD wds:Q37491576-91ED7922-CFE7-41AF-842C-E825C5E9FB5F wds:Q37491576-946FFA0A-1E93-4FD6-AA34-766713FDFCD8 wds:Q37491576-9743C731-EC1D-40BA-971C-586848171DDA wds:Q37491576-9984893B-8123-4A40-8053-CF3B52102432 wds:Q37491576-9A419B91-1E05-4A32-974E-D1E1138F5833 wds:Q37491576-9B963FF4-9B9E-4491-91D9-BB75299580D2 wds:Q37491576-9BA803FF-5944-4229-B025-95212088F309 wds:Q37491576-A2431A9C-70AA-47E7-B877-2F4CB48BC4A2 wds:Q37491576-A6CAE50F-22D2-4507-B6F2-F1F40ED4C11F wds:Q37491576-ABB31786-512D-4108-A72A-C190ACD0FBB5 wds:Q37491576-C5A1718F-1B3F-4946-9D70-4D7A4D6BF721 wds:Q37491576-D625B2FB-2BA3-4477-B926-A67CB4C4974F wds:Q37491576-D7427602-5617-4712-A671-EA04555481C8 wds:Q37491576-DCBFEB88-C07A-4543-A3B0-BC70BB6D60BD wds:Q37491576-DE7CFE7E-B7E0-4DFE-B594-6B7D97E0EB41 wds:Q37491576-E618D94C-C43B-4934-A832-4A7E328B18D5 wds:Q37491576-ECF6D93B-B62A-47D3-981D-F75B699E67F8 wds:Q37491576-ED5A3CC3-F9C9-42C9-9F82-D25950B36772
cites work	Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination Simultaneous binding of two different drugs in the binding pocket of the human multidrug resistance P-glycoprotein AcrB multidrug efflux pump of Escherichia coli: composite substrate-binding cavity of exceptional flexibility generates its extremely wide substrate specificity Cation-pi interactions in structural biology Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization Evidence for simultaneous binding of dissimilar substrates by the Escherichia coli multidrug transporter MdfA. Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug resistant cells Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling Antibody multispecificity mediated by conformational diversity Improved methods for building protein models in electron density maps and the location of errors in these models 2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity Structural mechanisms of QacR induction and multidrug recognition Crystal structure of bacterial multidrug efflux transporter AcrB A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QacA. Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites The use of circular dichroism in the investigation of protein structure and function. Fast prediction and visualization of protein binding pockets with PASS. The Cationminus signpi Interaction Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p The secondary multidrug transporter LmrP contains multiple drug interaction sites. Bioenergetics of the staphylococcal multidrug export protein QacA. Identification of distinct binding sites for monovalent and divalent cations. The millennium bugs--the need for and development of new antibacterials Mutually co-operative interactions between modulators of P-glycoprotein Dual Catalytic Apparatus of the Thiamin Diphosphate Coenzyme: Acid−Base via the 1‘,4‘-Iminopyrimidine Tautomer along with Its Electrophilic Role
author name string	wds:Q37491576-5E36B182-F203-45EE-8879-88955FDE6F5F wds:Q37491576-713CAD91-B6CC-42AB-A791-40B835E36AE1 wds:Q37491576-EAD86006-58B3-4B23-AE7D-B549F9935205
author name string	Maria A Schumacher Richard G Brennan Marshall C Miller
rdfs:label	Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (en) Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (nl) Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (ast)
skos:prefLabel	Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (en) Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (nl) Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (ast)
name	Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (en) Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (nl) Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (ast)
title	wds:Q37491576-C6D690B8-6695-4220-8F6A-347D669E54CB
title	Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein (en)
page(s)	wds:Q37491576-941BDE7A-6686-4563-BBB2-DFC659696F5C
page(s)	2923-2930

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