About: Potent block of Cx36 and Cx50 gap junction channels by mefloquine

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About: Potent block of Cx36 and Cx50 gap junction channels by mefloquine Goto Sponge NotDistinct Permalink

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description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) scholarly article (en) artículu científicu espublizáu en 2004 (ast) наукова стаття, опублікована в серпні 2004 (uk) 2004年學術文章 (zh) مقالة علمية نشرت في 05 أغسطس 2004 (ar)
publication date	wds:Q37485123-3EDA6CB2-5079-439A-BB14-4D884E5BDFD5
publication date	2004-08-05 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37485123-61B22691-0B7A-4CBE-ABC8-02985952BD79
language of work or name	English
cites work	wds:Q37485123-116E088A-E99D-4273-94A7-D0BDF19CF47E wds:Q37485123-13EF0A56-D7D7-42B6-991E-B582429E6373 wds:Q37485123-18E275E8-B568-42D9-905E-78742F5A847D wds:Q37485123-1A569E5D-69AA-42AD-A52A-7CC2651A7D0F wds:Q37485123-1C1998A0-23E7-4F99-9BAE-E4305AC3D587 wds:Q37485123-2A612511-06BF-4D8D-ACBC-0695C138F6B0 wds:Q37485123-305C9448-2EC8-4CA6-BE0A-04E3CA935AEE wds:Q37485123-30B38349-07C3-448D-AAB9-E9D3563FF745 wds:Q37485123-31D13D4C-930B-4882-BBFC-94039DC84D37 wds:Q37485123-3A341A5A-0523-4CDC-9BB2-9A2DD6D08158 wds:Q37485123-3B5A2AE7-BE88-4DDA-925A-E89D075B7D54 wds:Q37485123-4D5EB661-5A79-44F5-A1FE-02C7D71BDD20 wds:Q37485123-56A83D2C-ADAF-4F14-A526-CA16C44F1716 wds:Q37485123-619BC992-AE90-4303-8854-4A9B15AC2541 wds:Q37485123-65915DC5-AD81-496C-A2F0-281E8AAFAFE1 wds:Q37485123-7DB4D630-9944-49CB-ABF7-EF8290E137FE wds:Q37485123-8549369C-471F-4EE5-855F-5D957A98E334 wds:Q37485123-869AD99D-169D-42EF-A9E3-0EC91BA33712 wds:Q37485123-86B0440C-72DE-484D-91CC-9732454C6046 wds:Q37485123-878D7D55-2C69-4299-B98B-110A05918FFE wds:Q37485123-88BAA15D-F211-41A3-AC8F-4E43511997D3 wds:Q37485123-A1F7202D-C0F5-4941-AEE7-D205F65114F1 wds:Q37485123-A414CB3D-1AA4-400C-9100-8936BE958335 wds:Q37485123-A4340D17-60B1-4793-B2B8-37F02D4CEFB8 wds:Q37485123-A50B25C7-A07C-40B8-995F-52A9B634BFCC wds:Q37485123-AE4F82A4-1A20-47E5-B819-1A4CA4E9A8FD wds:Q37485123-B48FAB8C-C71C-4E23-BEB5-2518637CDD01 wds:Q37485123-B62E4B83-F327-416D-9A3D-80A8C2DBDA48 wds:Q37485123-C471A1B2-E464-408C-9D50-8FC694D2AD01 wds:Q37485123-C54336DB-07CB-4EB1-A34E-0C12268248C9 wds:Q37485123-D88DF6B1-9CA6-4C36-BEBD-CE64D9CEDCB4 wds:Q37485123-EA3A88E6-DC73-4854-90A3-DF33FEB7D549 wds:Q37485123-F49C8764-52B0-4A1C-B767-94E2CD4E4F87 wds:Q37485123-F4B054CA-7D8E-4C00-B901-176F55881CAA wds:Q37485123-F6978CFB-BF02-4F8B-97C7-32FFD7E4441B
cites work	Connexin36 is essential for transmission of rod-mediated visual signals in the mammalian retina Heteromeric connexons in lens gap junction channels A network of fast-spiking cells in the neocortex connected by electrical synapses Mefloquine. A review of its antimalarial activity, pharmacokinetic properties and therapeutic efficacy Immunogold evidence that neuronal gap junctions in adult rat brain and spinal cord contain connexin-36 but not connexin-32 or connexin-43. Synchronous Activity of Inhibitory Networks in Neocortex Requires Electrical Synapses Containing Connexin36 Structural and functional diversity of connexin genes in the mouse and human genome Clinical pharmacokinetics of mefloquine Targeted ablation of connexin50 in mice results in microphthalmia and zonular pulverulent cataracts. Impaired electrical signaling disrupts gamma frequency oscillations in connexin 36-deficient mice Two networks of electrically coupled inhibitory neurons in neocortex Unique and redundant connexin contributions to lens development Selective impairment of hippocampal gamma oscillations in connexin-36 knock-out mouse in vivo. The spatial dimensions of electrically coupled networks of interneurons in the neocortex Rhythmicity without synchrony in the electrically uncoupled inferior olive. Quinine blocks specific gap junction channel subtypes Carbenoxolone Blockade of Neuronal Network Activity in Culture is not Mediated by an Action on Gap Junctions Gap-junction-mediated propagation and amplification of cell injury. Electrical synapses in the thalamic reticular nucleus. Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel Effects of mefloquine on cardiac contractility and electrical activity in vivo, in isolated cardiac preparations, and in single ventricular myocytes Prospects for rational development of pharmacological gap junction channel blockers Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36. Reduction of high-frequency network oscillations (ripples) and pathological network discharges in hippocampal slices from connexin 36-deficient mice Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents Genetic diseases and gene knockouts reveal diverse connexin functions. Gap junctions mediate bystander cell death in developing retina Array analysis of gene expression in connexin-43 null astrocytes. Protein processing in lens intercellular junctions: cleavage of MP70 to MP38 The antimalarial agent mefloquine inhibits ATP-sensitive K-channels Inhibition of volume-regulated and calcium-activated chloride channels by the antimalarial mefloquine Deformation of network connectivity in the inferior olive of connexin 36-deficient mice is compensated by morphological and electrophysiological changes at the single neuron level. Molecular and cytogenetic characterization of a Chinese hamster/human hybrid cell line containing a der (21)t(Ypter-->cenY::cen21-->21qter) chromosome Block of transient outward-type cloned cardiac K+ channel currents by quinidine. Interactions of the antimalarial drug mefloquine with the human cardiac potassium channels KvLQT1/minK and HERG.
author name string	wds:Q37485123-097BD2D4-2BA7-4631-A433-6C3E961081B0 wds:Q37485123-6F4CA5A3-EFF9-4F4A-B774-CB5B80342F75 wds:Q37485123-A66F38C7-90FE-4BDF-8E66-8A90BC1B0F58 wds:Q37485123-E8A4D1FC-240D-4F60-84AD-2FDEB93BC322
author name string	David C Spray Miduturu Srinivas Scott J Cruikshank Matthew Hopperstad

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