About: A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice

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About: A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice Goto Sponge NotDistinct Permalink

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scientific article published on 19 August 2009

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rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2009 (ast) наукова стаття, опублікована в серпні 2009 (uk) scientific article published on 19 August 2009 (en) مقالة علمية نشرت في 19 أغسطس 2009 (ar)
publication date	wds:Q37410786-139954BC-9105-4D97-8307-A2BE1B95D2AB
publication date	2009-08-19 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37410786-B86E4611-233E-40E0-AFD9-4B4D247D7153
language of work or name	English
cites work	wds:Q37410786-04C5E318-E117-4B39-A88D-DB128EDE901B wds:Q37410786-1C91913D-72FF-4E21-9C7A-A5CBCCF2F420 wds:Q37410786-20170126-B0D4-43C6-82C0-DA73F91F7671 wds:Q37410786-275587DF-5B5F-425E-9B96-100F70B47BB0 wds:Q37410786-30DD0459-9740-4039-980A-4BAECFAAB57F wds:Q37410786-3607E30F-C134-403A-B6A6-3E363720D89F wds:Q37410786-3C5B227F-1B65-474F-82C7-99476A9BD22A wds:Q37410786-3E589CA0-7E07-4664-A9C2-E88C465079CA wds:Q37410786-42071B88-F35C-4A8A-AB49-A54F68F35E01 wds:Q37410786-440D5A82-4D08-467A-95B9-E172862C28CF wds:Q37410786-46EF8872-2443-40B8-A127-6324E7CFC5F4 wds:Q37410786-501FB7A9-AB0B-4AEA-85BD-B5B67572B5FD wds:Q37410786-56F76AC0-B4E3-4DBF-8EBD-74058491A03B wds:Q37410786-5D5AB2F1-A69C-4D0F-A146-5B5F3CC0F5ED wds:Q37410786-68F2CDAF-95F4-4767-A21C-0FDEB502D6CF wds:Q37410786-6ED63831-D386-4384-AE1C-CDFD826BA332 wds:Q37410786-6F71E45A-11D0-48CA-B900-D9A21412A429 wds:Q37410786-7150D722-BA4B-40AD-8F5A-F7A1D2205368 wds:Q37410786-787C7218-DF92-41C9-B541-EAA4884A4FDF wds:Q37410786-83292F17-9CBB-4498-A85C-F5D60F27351E wds:Q37410786-85031100-82D4-44B7-9A85-4757CD40E62A wds:Q37410786-98CCEC69-A976-4D8D-9704-59AF7946D8A0 wds:Q37410786-99F0774B-69B5-4101-83A8-9EAFAA88D152 wds:Q37410786-B9CD0C15-2E5C-467A-99E3-6A61F8726C79 wds:Q37410786-C3CF123C-AE81-4EE4-BEF2-C8012D629DB9 wds:Q37410786-D4BDC139-BCA4-485E-9752-8024FC57D6B9 wds:Q37410786-D9CF8D75-5365-47C0-819E-F408952075FF wds:Q37410786-DA594538-9370-4D8E-987F-D04F871E174B wds:Q37410786-F7809224-6E65-4492-B18B-C269C29914B2
cites work	A mouse model for the evaluation of pathogenesis and immunity to influenza A (H5N1) viruses isolated from humans An inhibitory activity in human cells restricts the function of an avian-like influenza virus polymerase. Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus. Depletion of lymphocytes and diminished cytokine production in mice infected with a highly virulent influenza A (H5N1) virus isolated from humans The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus Imaging of germinal center selection events during affinity maturation NKp46 and NKG2D recognition of infected dendritic cells is necessary for NK cell activation in the human response to influenza infection. A pandemic warning? Minimum information about a microarray experiment (MIAME)-toward standards for microarray data Utilization of pulse oximetry for the study of the inhibitory effects of antiviral agents on influenza virus in mice Germinal-center organization and cellular dynamics A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host. Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence H5-type influenza virus hemagglutinin is functionally recognized by the natural killer-activating receptor NKp44. Influenza virus infection augments NK cell inhibition through reorganization of major histocompatibility complex class I proteins Biological heterogeneity, including systemic replication in mice, of H5N1 influenza A virus isolates from humans in Hong Kong Evaluation of replication and pathogenicity of avian influenza a H7 subtype viruses in a mouse model Distinct pathogenesis of hong kong-origin H5N1 viruses in mice compared to that of other highly pathogenic H5 avian influenza viruses Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus Molecular correlates of influenza A H5N1 virus pathogenesis in mice Molecular changes in the polymerase genes (PA and PB1) associated with high pathogenicity of H5N1 influenza virus in mallard ducks The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04.
author name string	wds:Q37410786-A2B223B7-8DF4-47A6-83DA-5DFC142BE36F wds:Q37410786-BCF462EC-9C9F-4C30-B888-B601A5B6F45E wds:Q37410786-C2AAD27B-50FD-4738-80CA-5723699C7F44 wds:Q37410786-D73E832B-255C-441D-AC52-FE622B7F27FD wds:Q37410786-D8BFEBEC-0ED0-4055-A1C6-84D71DF21F9C wds:Q37410786-E78A6575-C589-4BD3-BE5D-634EFB33E092 wds:Q37410786-FFD39880-A29E-4671-98D9-D33728138D25
author name string	Victoria Carter Jerrold M Ward Sean Proll Jamie L Fornek Laura Gillim-Ross Celia Santos Lily I Cheng
rdfs:label	A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice. (nl) A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice (en) A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice (ast)
skos:prefLabel	A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice. (nl) A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice (en) A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice (ast)
name	A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice. (nl)

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