About: Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function

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About: Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function Goto Sponge NotDistinct Permalink

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scientific article published on August 1996

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 1996 (ast) 1996年學術文章 (zh) наукова стаття, опублікована в серпні 1996 (uk) مقالة علمية نشرت في أغسطس 1996 (ar) scientific article published on August 1996 (en)
publication date	wds:Q37385909-C24C56ED-064F-4A91-9D9C-B0236F7B79CA
publication date	1996-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37385909-5A0D277A-C5FF-4CF3-9000-835EE0CCF4DC
language of work or name	English
cites work	wds:Q37385909-0F796953-D95F-4CD2-B31E-D41F81A705DD wds:Q37385909-136C07DA-4D57-407C-BD71-3457ADB40858 wds:Q37385909-25B3107A-95C6-48BB-BEF7-C783E6E7C20D wds:Q37385909-2BAA934D-2EA8-4CED-A777-F720655A749A wds:Q37385909-52A744D6-86D2-4C1A-9AD4-2050EE5A717F wds:Q37385909-5B99367A-C999-4109-A954-E96DC2129B37 wds:Q37385909-5FA0D4D8-E8DF-4651-A8CF-EB58CB4E1C12 wds:Q37385909-676A401D-B127-46CB-89C6-097599D99F21 wds:Q37385909-6803CD40-51C6-4792-826D-56F228E41FB3 wds:Q37385909-6A185DF2-5FE6-4FB0-9C28-CE640A3F6BC8 wds:Q37385909-70736EF7-29D1-4B76-9827-F360C69A8630 wds:Q37385909-72DB6C18-9411-456F-B0A7-D549C5529361 wds:Q37385909-7846FBDC-E4CF-4E79-B252-E89F36DBB14A wds:Q37385909-792DFA14-2491-4ABB-BC05-BBAB93EDCB65 wds:Q37385909-7E3035D3-C614-4E44-890A-FC8D90AA8C9C wds:Q37385909-85C49F0C-A13D-482B-996B-DD10AC59D545 wds:Q37385909-90274180-0397-4C43-B88A-255D9025BD9E wds:Q37385909-96630DFB-4ACF-4F49-A8B9-AB857813752C wds:Q37385909-99AA50A7-E51D-4C91-BA3A-EE79EC73A739 wds:Q37385909-9B4E0BD9-5955-4527-965B-C60EC8F1410A wds:Q37385909-9D760168-6740-43AA-A17F-CCD9EBCB684B wds:Q37385909-9D7AAAA2-54AC-43B5-A783-84D646300E68 wds:Q37385909-A600091E-D94A-457D-93C0-F887D2D0FA9F wds:Q37385909-B41C4ACA-5366-4E90-AEED-DA81386833F1 wds:Q37385909-B4F67FD1-E9F9-41B7-9340-FDEA0C186A71 wds:Q37385909-C8AD0066-5F4A-480A-9876-573A307D141C wds:Q37385909-CD00EBA9-B370-41C2-823C-933C13C18975 wds:Q37385909-E554DB4E-B53F-4468-A8E2-128FF18DAD93 wds:Q37385909-E8E6409F-4FCC-492C-86D2-1030D52B2504 wds:Q37385909-EBC6BD41-BE0E-49C5-A986-7C5AD43D8F93 wds:Q37385909-EDFE4009-062D-4DC0-8D9D-AFBE6281058C wds:Q37385909-FC31CE5E-8996-44BC-B8DE-9B1B7B47DC55 wds:Q37385909-FDC57531-3700-4193-82FF-53DAAE4D1A9B wds:Q37385909-FE1561B6-24B3-4617-97A3-64AD517B7C10
cites work	Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen. Functional recognition of in vivo processed self antigen Limited capacity for tolerization of CD4+ T cells specific for a pancreatic beta cell neo-antigen. Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction. Expression of two T cell receptor α chains on the surface of normal murine T cells Expression of two T cell receptor alpha chains: dual receptor T cells T cells with dual antigen specificity in T cell receptor transgenic mice rejecting allografts Positive and negative selection of an antigen receptor on T cells in transgenic mice. Molecular mimicry and autoimmune disease Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes Mouse T-cell receptor variable gene segment families High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice B cells solicit their own help from T cells. T cells with two functional antigen-specific receptors Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen Autoimmune diseases: the failure of self tolerance The JAM test. A simple assay for DNA fragmentation and cell death Each of the two productive T cell receptor alpha-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an alpha chain which can contribute to the constitution of a surface-expressed alpha beta dimer. Infection breaks T-cell tolerance. Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor Exclusion and inclusion of α and β T cell receptor alleles Following a diabetogenic T cell from genesis through pathogenesis Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity Self-nonself discrimination by T cells Peripheral tolerance as a multi-step mechanism Preferential positive selection of V alpha 2+ CD8+ T cells in mouse strains expressing both H-2k and T cell receptor V alpha a haplotypes: determination with a V alpha 2-specific monoclonal antibody. Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice Dual T cell receptor alpha chain T cells in autoimmunity Induction of tolerance to self MHC class I molecules expressed under the control of milk protein or beta-globin gene promoters Allelic exclusion of alpha chains in TCRs Clonal deletion of specific thymocytes by an immunoglobulin idiotype.
author name string	wds:Q37385909-0587E7D8-6B6E-4A85-88E9-D285440DDBBC wds:Q37385909-183E12F2-8912-4EBA-B6AB-91E98434353C wds:Q37385909-EBC20BCF-39D9-47DD-805C-CBEBEF45E381 wds:Q37385909-FD9FBCD6-59A9-4A6E-BFB4-E8B03B334BA0
author name string	Weiss S Mellor A Stockinger B Zal T
rdfs:label	Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function (en) Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function (nl)

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