About: Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo

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About: Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo Goto Sponge NotDistinct Permalink

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scientific article published on December 1996

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 1996 (ast) наукова стаття, опублікована в грудні 1996 (uk) مقالة علمية نشرت في ديسمبر 1996 (ar) scientific article published on December 1996 (en)
publication date	wds:Q37362126-D30FC485-3247-4B9F-8D5A-87E059192672
publication date	1996-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37362126-9530E63A-8485-49C2-9758-7697C49D51FC
language of work or name	English
cites work	wds:Q37362126-02F274CC-ED28-41D4-98B4-25930679457A wds:Q37362126-036B8C63-DF96-45FB-96EF-8DE02083A2F3 wds:Q37362126-037ADEE5-DF14-4FEB-8C6A-15385164422C wds:Q37362126-09B53494-6DE1-4C8B-88DB-240E96201F62 wds:Q37362126-3204D693-A948-4B5F-9C5D-5C6C6D836383 wds:Q37362126-35CB1E4A-07ED-41C2-84F1-4D310EFBBBEE wds:Q37362126-53536F93-DA19-421E-86A5-4629E5072D8C wds:Q37362126-56A4AC1B-6749-4333-A6F2-0604ED0CEA83 wds:Q37362126-5F634CE2-B2F0-432D-BEAE-5298F3459B11 wds:Q37362126-6435DC6D-22ED-4080-9C6F-A87FA581C9F6 wds:Q37362126-6867B70A-DB81-4603-8C96-95F43A7068E6 wds:Q37362126-69F38F48-9194-4356-A05B-42976D86D3DF wds:Q37362126-7525206A-533A-4F55-826D-3C1AC650AA94 wds:Q37362126-7E36D9C0-542F-4382-82A3-9D2D2059B9BB wds:Q37362126-8D7F7F44-16FA-4096-B709-AF2C99D1B299 wds:Q37362126-994C9034-8DD7-48CE-9663-7BAA3F863D40 wds:Q37362126-9CEB085A-D4DA-4FDA-AC60-F1E2A0817805 wds:Q37362126-9F5DCC71-C088-4616-8936-532A58625BD3 wds:Q37362126-A13C3AFC-21A2-4CF8-8526-46E88D0773FF wds:Q37362126-A38698A2-48D4-48ED-BEF8-9B8001489307 wds:Q37362126-AC2017E2-E1D1-40C0-911A-186EEBB2794F wds:Q37362126-ADAEC635-95DA-41B9-8641-AC12C6290939 wds:Q37362126-AE57EAC3-71D8-4FE8-8B33-5CC5D42B664B wds:Q37362126-B4AC4EB8-CA71-4DDD-8F48-E1910B130C06 wds:Q37362126-B98A24E5-CE85-41FD-BD91-5143081B99E8 wds:Q37362126-C4F53C02-35E4-4076-9FF0-152924A6C84D wds:Q37362126-C917720D-39D8-461C-839F-BDEE744C7318 wds:Q37362126-D38336DC-6C25-49D5-A089-F3261C5D68BC wds:Q37362126-DE24561E-0F34-437E-8959-5139DF54201E wds:Q37362126-E44F9561-C16E-47D8-992E-865716DBEBC9 wds:Q37362126-F2A8D0A7-4478-4772-B8F7-F6A190BC7A83 wds:Q37362126-F5E91EAD-D128-48AF-82DC-62E91D69B564
cites work	Increased production and immunohistochemical localization of transforming growth factor-beta in idiopathic pulmonary fibrosis. Extracellular matrix and the regulation of lung development and repair 1 Macrophage production of transforming growth factor beta and fibroblast collagen synthesis in chronic pulmonary inflammation Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis Relaxin binding in the rat heart atrium Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene Simple method of estimating severity of pulmonary fibrosis on a numerical scale Collagen concentration and rates of synthesis in idiopathic pulmonary fibrosis Bleomycin-induced pulmonary fibrosis. Effects of steroid on lung collagen metabolism Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts Relaxin alone and in conjunction with interferon-gamma decreases collagen synthesis by cultured human scleroderma fibroblasts Relaxin stimulates myometrial calcium-activated potassium channel activity via protein kinase A. Bleomycin-induced injury and metaplasia of alveolar type 2 cells. Relationship of cellular responses to drug presence in the lung Human relaxin decreases collagen accumulation in vivo in two rodent models of fibrosis Bleomycin-induced pulmonary fibrosis: Correlation of biochemical, physiological, and histological changes Influences of gamma interferon on synovial fibroblast-like cells. Ia induction and inhibition of collagen synthesis Utilization of the releaxed symphysis pubis of guinea pigs for clues to the mechanism of ovulation TGF-beta: problems and prospects The effects of oestradiol and relaxin on extensibility and collagen organisation of the pregnant rat cervix Production and function of murine macrophage inflammatory protein-1 alpha in bleomycin-induced lung injury Effects of relaxin on mast cells. In vitro and in vivo studies in rats and guinea pigs Relaxin stimulates interstitial collagenase activity in cultured uterine cervical cells from nonpregnant and pregnant but not immature guinea pigs; estradiol-17 beta restores relaxin's effect in immature cervical cells. Intratracheal versus intravenous administration of bleomycin in mice: acute effects New perspectives on basic mechanisms in lung disease. 1. Lung injury, inflammatory mediators, and fibroblast activation in fibrosing alveolitis Human relaxin increases cyclic AMP levels in cultured anterior pituitary cells The many faces of an increase in lung collagen Relaxin in human pregnancy serum measured with an homologous radioimmunoassay Cyclic AMP response to recombinant human relaxin by cultured human endometrial cells—A specific and high throughput in vitro bioassay Collagenase expression and endogenous activation in rabbit synovial fibroblasts stimulated by the calcium ionophore A23187. Prevention of bleomycin-induced fibrosing alveolitis with indomethacin: Stereological studies on rat lungs The effect of relaxin on tissue expansion Phorbol ester, prolactin, and relaxin cause translocation of protein kinase C from cytosol to membranes in human endometrial cells
author name string	wds:Q37362126-02EC5D61-7B5E-4EF1-A624-A279C4D051E2 wds:Q37362126-42A8F7A8-00C3-471B-AF72-A9BB674270FF wds:Q37362126-4ADD993F-AEFF-4669-B134-4AA0D9741A21 wds:Q37362126-5336AD3A-8672-4719-9FCA-9E1F387E8EB6 wds:Q37362126-80547D9E-6C92-4C25-A59D-9969C3C75263 wds:Q37362126-C17E3F20-F067-4DDF-90EC-E9243A03CEFF wds:Q37362126-DA61276C-4B8A-41FC-AD6C-466FAF3AB9D6
author name string	Amento EP Unemori EN Erikson ME Grove BH Pickford LB Piercy CE Salles AL
rdfs:label	Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo (en)

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