About: Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo

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About: Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo Goto Sponge NotDistinct Permalink

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scientific article published on February 2003

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2003 (ast) наукова стаття, опублікована в лютому 2003 (uk) مقالة علمية نشرت في فبراير 2003 (ar) scientific article published on February 2003 (en)
publication date	wds:Q37354988-21D1C134-12A1-4438-B364-1CB3890EB9BC
publication date	2003-02-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37354988-72051452-8DF1-4D5E-BF11-0C876A6FF532
language of work or name	English
exact match	wds:Q37354988-4EE6278B-2700-4205-A490-E90FA96FFC5A
exact match	https://scigraph.springernature.com/pub.10.1038/sj.bjc.6600719
cites work	wds:Q37354988-0BD20825-A7FE-4886-8BBF-E8FE0A85F9F8 wds:Q37354988-1771347E-B751-4E1E-A5FF-20EE9DB08201 wds:Q37354988-2540B33E-0A8C-4FAD-AD44-406F45F33F54 wds:Q37354988-2F6B0887-AF67-4789-92C1-80986536DF57 wds:Q37354988-33A7D28D-A8F2-4A65-93BC-AB41FDE07A11 wds:Q37354988-3BA34B7B-FE70-4D47-BF3F-3B4FDC79A353 wds:Q37354988-3CB3AB17-23D6-4A30-B939-86441EC4048D wds:Q37354988-49028BB6-6012-4AB6-AD30-7E350B2F45F7 wds:Q37354988-4D0FA8DB-4A64-4C5B-8064-738D4BD7D3CE wds:Q37354988-521279E4-C6AD-42A9-80E4-2733D43DBD82 wds:Q37354988-55484C1B-1EFB-407C-A9E0-CE643D5533A6 wds:Q37354988-5CB8493F-A3B7-464B-B1F5-3509ABD01E18 wds:Q37354988-5FBC2A58-D038-4ECE-B0C4-03659F62FA12 wds:Q37354988-634C5F45-1076-4BAA-BA53-D1FC3D11443E wds:Q37354988-640FE5F1-6469-4ADC-9F71-9FD05600C678 wds:Q37354988-8FF6C9C2-7890-4B35-98CB-F7F6A7C22A2D wds:Q37354988-94D6DC5E-B05D-4A67-8336-BA04979C1F2C wds:Q37354988-99EEB6B7-3844-4015-93E9-7EC80953C008 wds:Q37354988-AE721007-ED45-4690-B767-83319F8B988A wds:Q37354988-BC29F71F-7795-484D-B7F8-DD3040801767 wds:Q37354988-BE9D1D77-0A97-477A-AC47-7C52CAB80E6D wds:Q37354988-D66998DF-6860-472A-8358-DFEF10FCE2AF wds:Q37354988-EA7D3C44-0ABE-4ACB-86EB-C254D02CCE88 wds:Q37354988-FD6807A4-CA82-4E3B-98B2-5D7E8C7AF530 wds:Q37354988-FEE80A41-B48C-46C3-AEDA-83811FFE6A86
cites work	Influence of 2-(4-aminophenyl)benzothiazoles on growth of human ovarian carcinoma cells in vitro and in vivo Studies of the murine DDB1 and DDB2 genes Human damage-specific DNA-binding protein p48. Characterization of XPE mutations and regulation following UV irradiation. Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts. Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1. Recombinant human cytochrome P450 1B1 expression in Escherichia coli Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner Antitumor benzothiazoles. 8. Synthesis, metabolic formation, and biological properties of the C- and N-oxidation products of antitumor 2-(4-aminophenyl)benzothiazoles Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles Antitumor benzothiazoles. 16. Synthesis and pharmaceutical properties of antitumor 2-(4-aminophenyl)benzothiazole amino acid prodrugs Antitumor benzothiazoles. 7. Synthesis of 2-(4-acylaminophenyl)benzothiazoles and investigations into the role of acetylation in the antitumor activities of the parent amines Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1. 2-(4-Aminophenyl)benzothiazoles: novel agents with selective profiles of in vitro anti-tumour activity Evaluation of tamoxifen and alpha-hydroxytamoxifen 32P-post-labelled DNA adducts by the development of a novel automated on-line solid-phase extraction HPLC method. Investigation of the formation and accumulation of liver DNA adducts in mice chronically exposed to tamoxifen. Enhanced sensitivity of 32P-postlabeling analysis of aromatic carcinogen:DNA adducts. In vitro evaluation of amino acid prodrugs of novel antitumour 2-(4-amino-3-methylphenyl)benzothiazoles. Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles. Mechanisms of acquired resistance to 2-(4-aminophenyl)benzothiazole (CJM 126, NSC 34445) Role of Cyp1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells The 1992 Bernard B. Brodie Award Lecture. Bioactivation and detoxication of toxic and carcinogenic chemicals. Induction of CYP1A1 in tumor cells by the antitumor agent 2-[4-amino-3-methylphenyl]-5-fluoro-benzothiazole: a potential surrogate marker for patient sensitivity.
author name string	wds:Q37354988-08616513-A8FB-47E6-9714-BB049AFB1E58 wds:Q37354988-2C2D85F4-15F6-42E4-A08F-597980A1FAB4 wds:Q37354988-39813FB1-F008-4910-A8D9-816C053C280C wds:Q37354988-797B06D3-9318-4271-B46B-3E204C38EE36 wds:Q37354988-81AF0707-4130-447C-ADE7-0CD292F74F0B wds:Q37354988-8CB54612-204C-463B-A779-4D970EF547C0 wds:Q37354988-A000202F-D3B5-4914-B302-B4FDABC8D0C2 wds:Q37354988-C73AA2FF-88AB-431D-8042-E608F4478575 wds:Q37354988-C861A5A2-F836-4791-862D-B9072BF6F4A6 wds:Q37354988-FF5E80F3-E018-40CE-B45C-E1595C0EB1B4
author name string	J A Double M C Bibby C-O Leong M F G Stevens P B Farmer E A Martin T D Bradshaw P A Cooper M Gaskell R T Heydon
rdfs:label	Antitumour 2- (nl) Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo (en) Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo (ast)
skos:prefLabel	Antitumour 2- (nl) Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo (en) Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo (ast)
name	Antitumour 2- (nl)

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