About: A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine.

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About: A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. Goto Sponge NotDistinct Permalink

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scientific article published on 14 May 2008

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rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2008 (ast) наукова стаття, опублікована в травні 2008 (uk) scientific article published on 14 May 2008 (en) مقالة علمية نشرت في 14 مايو 2008 (ar)
publication date	wds:Q37241136-525A39E6-7A06-4BB9-9124-2E49DD483C35
publication date	2008-05-14 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37241136-3FEEBE3E-B8D1-4DC4-B9F6-B1942CCAD124
language of work or name	English
cites work	wds:Q37241136-00B9EB11-3807-4F7B-8088-24D38203677B wds:Q37241136-042583D7-1EEE-4D42-84AA-CCBEF0FB69C5 wds:Q37241136-058C3AA1-FDE3-4BDC-9C74-C8A37A5490A9 wds:Q37241136-18C0062A-A81D-47A5-A2D9-1B02A9319989 wds:Q37241136-1B41C3D6-844C-43C7-B7A6-53A804A6743C wds:Q37241136-214E7251-F51B-4B4F-B394-35E51E37D582 wds:Q37241136-220BAB4C-B323-4E74-8D24-499006DAF529 wds:Q37241136-2261E785-B751-4E53-97FE-7B08A5FCFDAB wds:Q37241136-2B2A66FF-681C-428F-9A2B-DBC9719634EB wds:Q37241136-3D432364-BBA1-4F30-A424-957AB1176825 wds:Q37241136-427CEDA0-C2BA-412E-B5DA-364BE198FBD3 wds:Q37241136-476CD16E-D1C9-473F-8F15-805FABE02514 wds:Q37241136-584B8C8F-1E65-4990-AB5B-853EB6B7590C wds:Q37241136-59BABCAC-4C87-48A7-8890-E812C9F24747 wds:Q37241136-61A93074-1C25-4514-9CE2-E6F1D485C84C wds:Q37241136-62522454-89B6-471B-9163-7FCF74D7A8F3 wds:Q37241136-6BE3F8F2-E23F-43D9-81E3-E68663D93641 wds:Q37241136-73988C51-3D90-421A-9DFC-39D0F7F1F04B wds:Q37241136-79D4EE9E-AC78-47CE-BC68-F65CE9CD9702 wds:Q37241136-907E7068-0503-4D5C-9992-5383C388121A wds:Q37241136-98D4DB41-8480-45B9-B2BC-C1B51286E951 wds:Q37241136-A3020B7D-B57F-4FB9-BA0A-2DADFBFA6B95 wds:Q37241136-A7D7BD7C-AAD0-4C97-A74C-B67632987920 wds:Q37241136-B2AA358F-6A75-40BC-AAE6-880ABFA514D7 wds:Q37241136-C25E2E0F-FCF9-485E-B3E5-A3CB83C246AD wds:Q37241136-DA3A01CD-EF41-4D05-A09A-01AFDB2DE6FC wds:Q37241136-EC4BD91F-F24E-4C69-844F-936142DAE68B wds:Q37241136-ED43C060-DFC7-41B1-8E12-E868E7542209 wds:Q37241136-EF2ED447-1462-44B0-8668-99B82377AE52 wds:Q37241136-FA0E82DD-57DA-4E87-9E73-A0D53F3B187C wds:Q37241136-FA328D90-1755-45D3-A6C8-47D599FE85DC wds:Q37241136-FCE73EFE-0D23-424B-BBCD-D72996FEAB48
cites work	Influenza virus M2 protein has ion channel activity The closed state of a H+ channel helical bundle combining precise orientational and distance restraints from solid state NMR The M2 channel of influenza A virus: a molecular dynamics study Molecular dynamics simulation of proton transport through the influenza A virus M2 channel Exploring models of the influenza A M2 channel: MD simulations in a phospholipid bilayer Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide Proton transport through influenza A virus M2 protein reconstituted in vesicles Experimentally based orientational refinement of membrane protein models: A structure for the Influenza A M2 H+ channel Influenza A virus M2 ion channel protein: a structure-function analysis HOLE: a program for the analysis of the pore dimensions of ion channel structural models Histidines, heart of the hydrogen ion channel from influenza A virus: toward an understanding of conductance and proton selectivity. The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus Structural characteristics of the M2 protein of influenza A viruses: evidence that it forms a tetrameric channel Cu(II) inhibition of the proton translocation machinery of the influenza A virus M2 protein Influenza virus M2 protein: a molecular modelling study of the ion channel. Neutron diffraction reveals the site of amantadine blockade in the influenza A M2 ion channel. Structure and mechanism of the M2 proton channel of influenza A virus Solid-state NMR and MD simulations of the antiviral drug amantadine solubilized in DMPC bilayers Structural basis for the function and inhibition of an influenza virus proton channel The gate of the influenza virus M2 proton channel is formed by a single tryptophan residue Activation of the M2 ion channel of influenza virus: a role for the transmembrane domain histidine residue A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes Backbone Structure of the Amantadine-Blocked Trans-Membrane Domain M2 Proton Channel from Influenza A Virus Transmembrane domain of M2 protein from influenza A virus studied by solid-state (15)N polarization inversion spin exchange at magic angle NMR The M2 proton channels of influenza A and B viruses Proton transport behavior through the influenza A M2 channel: insights from molecular simulation Structure and dynamics of a proton wire: a theoretical study of H+ translocation along the single-file water chain in the gramicidin A channel Sequence determinants of a transmembrane proton channel: an inverse relationship between stability and function A computational study of the closed and open states of the influenza a M2 proton channel How pH opens a H+ channel: the gating mechanism of influenza A M2. A novel method of resistance for influenza against a channel-blocking antiviral drug.
author name string	wds:Q37241136-5406BD0A-B6BC-41E9-AD30-696F224748AC wds:Q37241136-6C70B603-F454-4F51-A25E-8604C2859B3C
author name string	Timothy A Cross Myunggi Yi
rdfs:label	A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. (en) A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. (nl) A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. (ast)
skos:prefLabel	A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. (en) A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. (nl) A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. (ast)
name	A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. (en) A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. (nl) A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. (ast)
author	wds:Q37241136-DCEAB233-431E-4DCC-8A61-A4BF66E05990
author	Huan-Xiang Zhou

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