About: Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist

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About: Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist Goto Sponge NotDistinct Permalink

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scientific article published on 30 July 2013

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2013 (ast) наукова стаття, опублікована в липні 2013 (uk) scientific article published on 30 July 2013 (en) مقالة علمية نشرت في 30 يوليو 2013 (ar)
publication date	wds:Q37230805-CB7285EA-2867-4DE4-8476-30AADD73AB7C
publication date	2013-07-30 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37230805-8DFA8FF7-F315-459F-8431-734D1B627722
language of work or name	English
cites work	wds:Q37230805-0227B323-E3DD-4759-979B-5C77D3C68486 wds:Q37230805-19CE6699-BB2D-4692-97AC-D94912022C2A wds:Q37230805-1A7F60C8-6F9B-4EE7-92E3-FE7FAB16F1C7 wds:Q37230805-1AEB6FA0-1D07-4B69-BBB9-D2EE7C01483E wds:Q37230805-27EBED65-F0A6-49E3-8B94-7728867AB163 wds:Q37230805-2AD3B232-38D9-4861-9B07-DA9B338FCB29 wds:Q37230805-2CF2E000-95D8-4B8B-AF2A-35638F60B9C3 wds:Q37230805-4AADBB1B-BF13-4669-AE0E-04AA150B2DCD wds:Q37230805-67E17D35-5C52-4461-BE89-E6C5F49CC08A wds:Q37230805-69B657EC-7835-46AC-86BB-04A08B8A37D6 wds:Q37230805-6B45FEA3-CA26-4297-89FE-52BCDEE0A0D4 wds:Q37230805-6C779524-96E6-4004-87B5-7A8D3646715D wds:Q37230805-896A0EAA-56F1-4A6D-8C1E-B1392103C46C wds:Q37230805-92085FE0-0434-464F-B3B5-B091195D0A78 wds:Q37230805-9C3E1B1B-841D-4E3B-8DA0-B56878184D43 wds:Q37230805-A225E19B-A7FF-46DF-B4D4-1221D33D6663 wds:Q37230805-B61BFDF3-9BDB-4362-B8AE-441A8539E40C wds:Q37230805-BFD4820F-CE1B-4E76-941D-68F7777B4B9C wds:Q37230805-C4CCDDEE-180F-4E35-9F9B-81AA9FBCB9B8 wds:Q37230805-C5B6E091-9CEF-46D1-A6FE-960401749317 wds:Q37230805-CBCECB5E-A071-46A0-A476-4FF4D03279E9 wds:Q37230805-D6035C42-0136-459E-88E2-B1150780194B wds:Q37230805-E2DE88A7-640D-4610-9D01-2C1A692CE979 wds:Q37230805-E6318436-1EEC-4773-A873-E3668BB0092E wds:Q37230805-EBF2C355-8EE0-48A2-AB7A-B808024DCC7B wds:Q37230805-ED595536-327D-4EA1-BD73-BDEA7D64F4A0 wds:Q37230805-EF1456BE-6AE5-4213-8AE4-60834DE939F3 wds:Q37230805-F3690788-3244-4843-A2A3-641B74501927 wds:Q37230805-FA5F788C-4C58-4DDD-8317-830FD1705E6D
cites work	Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor Corneal avascularity is due to soluble VEGF receptor-1 Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice Signal transduction by vascular endothelial growth factor receptors Inhibitors of the biosynthesis and processing of N-linked oligosaccharide chains Perturbation of vesicular traffic with the carboxylic ionophore monensin A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is up-regulated in hypoxia and preeclampsia Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium Intronic polyadenylation signal sequences and alternate splicing generate human soluble Flt1 variants and regulate the abundance of soluble Flt1 in the placenta. Regulated intramembrane proteolysis: signaling pathways and biological functions Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1 Membrane fixation of vascular endothelial growth factor receptor 1 ligand-binding domain is important for vasculogenesis and angiogenesis in mice VEGF-receptor signal transduction Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation Local guidance of emerging vessel sprouts requires soluble Flt-1 γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells. Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis. Local retention versus systemic release of soluble VEGF receptor-1 are mediated by heparin-binding and regulated by heparanase. Heparin Strongly Induces Soluble Fms-Like Tyrosine Kinase 1 Release In Vivo and In Vitro—Brief Report Identification of ligand-induced proteolytic cleavage and ectodomain shedding of VEGFR-1/FLT1 in leukemic cancer cells Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Alternate processing of Flt1 transcripts is directed by conserved cis-elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation. Alternative Splicing of Vascular Endothelial Growth Factor (VEGF)-R1 (FLT-1) pre-mRNA Is Important for the Regulation of VEGF Activity A novel intracellular isoform of VEGFR-1 activates Src and promotes cell invasion in MDA-MB-231 breast cancer cells Secretion of soluble vascular endothelial growth factor receptor 1 (sVEGFR1/sFlt1) requires Arf1, Arf6, and Rab11 GTPases
author name string	wds:Q37230805-901A6B9E-1E9C-4CFA-8B43-4ABDF8D491A4 wds:Q37230805-DF879D72-8B6D-4301-8D44-F3F03D7D4437
author name string	Nandita S Raikwar Kang Z Liu
rdfs:label	Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist (en) Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist (ast) Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist. (nl)
skos:prefLabel	Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist (en) Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist (ast) Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist. (nl)
name	Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist (en) Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist (ast) Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist. (nl)
author	wds:Q37230805-415B6444-7330-4FAC-8E7F-1C2A460D7FD0
author	Christie Thomas
title	wds:Q37230805-82731AAB-EA41-4893-AE91-685D0ECEEDFD
title	Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist (en)
page(s)	wds:Q37230805-2CDD9AFC-F01C-462C-9CCC-2BCFF39C4C97
page(s)	2578-2587
instance of	wds:Q37230805-E53BCE8A-271C-4361-8AC5-08D6619DCC39
instance of	scholarly article

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