About: Isocyanide-based multicomponent reactions in drug discovery

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scientific article published on 14 March 2008

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2008 (ast) наукова стаття, опублікована в березні 2008 (uk) مقالة علمية نشرت في 14 مارس 2008 (ar) scientific article published on 14 March 2008 (en)
publication date	wds:Q37099268-EFA308B2-A8B8-4300-A4BA-157BAA11F484
publication date	2008-03-14 00:00:00Z (xsd:dateTime)
author name string	wds:Q37099268-4FC33211-8B3E-4F6A-8E5F-08617254ED6C
author name string	Irini Akritopoulou-Zanze
rdfs:label	Isocyanide-based multicomponent reactions in drug discovery (en) Isocyanide-based multicomponent reactions in drug discovery (nl) Isocyanide-based multicomponent reactions in drug discovery (ast)
skos:prefLabel	Isocyanide-based multicomponent reactions in drug discovery (en) Isocyanide-based multicomponent reactions in drug discovery (nl) Isocyanide-based multicomponent reactions in drug discovery (ast)
name	Isocyanide-based multicomponent reactions in drug discovery (en) Isocyanide-based multicomponent reactions in drug discovery (nl) Isocyanide-based multicomponent reactions in drug discovery (ast)
title	wds:Q37099268-F0A9D5AE-306C-47F7-8EFB-BBF03F9CFA77
title	Isocyanide-based multicomponent reactions in drug discovery (en)
page(s)	wds:Q37099268-10EBDC39-0434-41AB-A07D-234998D7B696
page(s)	324-331
instance of	wds:Q37099268-A2A228F1-5FFC-4A7F-8B75-B45A56E0C00D wds:Q37099268-acbefc2c-3bc0-4d51-80b8-0c8bcb5efd51
instance of	review article scholarly article
main subject	wds:Q37099268-5016C45F-8561-4434-A798-52752DE00D75
main subject	drug discovery
PubMed ID	wds:Q37099268-CD94A422-612E-4FA8-98A3-C0E8259F3C74
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18312861
PubMed ID	18312861
published in	wds:Q37099268-1897A9B6-27EA-4718-B432-ADF0E9C2DB7F
published in	Current Opinion in Chemical Biology
issue	wds:Q37099268-E1AF58C2-AB80-423A-BF04-E35AF17EF787
volume	wds:Q37099268-8EBB46A2-2A7A-49F7-84D6-0892EAE95C42
issue	3
volume	12
DOI	wds:Q37099268-648C3E87-6334-4438-A913-8A77E4B30E38
DOI	http://dx.doi.org/10.1016/J.CBPA.2008.02.004
DOI	10.1016/J.CBPA.2008.02.004
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q37099268
is cites work of	Ugi/Robinson–Gabriel reactions directed toward the synthesis of 2,4,5-trisubstituted oxazoles Microfluidic platform for combinatorial synthesis in picolitre droplets Chemistry and biology of multicomponent reactions. Ugi-Smiles couplings: new entries to N-aryl carboxamide derivatives. Three-component asymmetric catalytic Ugi reaction--concinnity from diversity by substrate-mediated catalyst assembly. Hydrazine-mediated cyclization of Ugi products to synthesize novel 3-hydroxypyrazoles A conceptual framework for analysing and planning synthetic approaches to diverse lead-like scaffolds Catalyst-free sonosynthesis of highly substituted propanamide derivatives in water. One-pot synthesis of tetracyclic fused imidazo[1,2-a]pyridines via a three-component reaction Groebke-Blackburn-Bienaymé multicomponent reaction: emerging chemistry for drug discovery. A chemoselective Ugi-type reaction in water using TMSCN as a functional isonitrile equivalent: generation of heteroaromatic molecular diversity Novel, fast and efficient one-pot sonochemical synthesis of 2-aryl-1,3,4-oxadiazoles Synthesis of diverse nitrogen-enriched heterocyclic scaffolds using a suite of tunable one-pot multicomponent reactions Synthesis of polyheterocycles via multicomponent reactions. Multicomponent reactions in nucleoside chemistry. Highly stereoselective synthesis of natural-product-like hybrids by an organocatalytic/multicomponent reaction sequence. Organocatalytic asymmetric epoxidation and tandem epoxidation/Passerini reaction under eco-friendly reaction conditions. Combinatorial multicomponent access to natural-products-inspired peptidomimetics: discovery of selective inhibitors of microbial metallo-aminopeptidases. Efficient metal-free synthesis of various pyrido[2',1':2,3]imidazo- [4,5-b]quinolines An Ugi Reaction Incorporating a Redox-Neutral Amine C-H Functionalization Step Polycyclic compounds by Ugi-Pictet-Spengler sequence. The Pictet-Spengler Reaction Updates Its Habits Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer's disease therapy Synthesis of Imidazole-Based Medicinal Molecules Utilizing the van Leusen Imidazole Synthesis Synergy Effects in the Chemical Synthesis and Extensions of Multicomponent Reactions (MCRs)-The Low Energy Way to Ultra-Short Syntheses of Tailor-Made Molecules. Straightforward assembly of phenylimidazoquinoxalines via a one-pot two-step MCR process Multicomponent synthesis of dihydrobenzoxazepinones, bearing four diversity points, as potential α-helix mimics Hexafluoroisopropanol as the Acid Component in the Passerini Reaction: One-Pot Access to β-Amino Alcohols. The Catalytic Enantioselective Ugi Four-Component Reactions Exploiting the Divalent Nature of Isonitriles: a novel Pictet-Spengler Amidination process Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold Reaction of isocyanides with thiophenols and gem-diactivated olefins: a one-pot synthesis of substituted 2-aminopyrroles Synthesis of diversely substituted 2-(furan-3-yl)acetates from allenols through cascade carbonylations. A practical and efficient approach to imidazo[1,2-a]pyridine-fused isoquinolines through the post-GBB transformation strategy New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized. Synthesis of Novel Fluorene Bisamide Derivatives via Ugi Reaction and Evaluation their Biological Activity against Mycobacterium species Catalyst free, C-3 functionalization of imidazo[1,2-a]pyridines to rapidly access new chemical space for drug discovery efforts Gold Catalyzed Multicomponent Reactions beyond A³ Coupling One-pot synthesis of benzochromeno-pyrazole derivatives With unprotected amino acids to tetrazolo peptidomimetics. Recent Advances in the Reactions of 1,2-Allenic Ketones and α-Allenic Alcohols. Nucleophilic Isocyanation Stereoselective synthesis of N-aryl proline amides by biotransformation–Ugi-Smiles sequence Toward synthesis of third-generation spin-labeled podophyllotoxin derivatives using isocyanide multicomponent reactions 2-Nitrobenzyl Isocyanide as a Universal Convertible Isocyanide. High-throughput polymer screening in microreactors: boosting the Passerini three component reaction A Focused Library of NO-Donor Compounds with Potent Antiproliferative Activity Based on Green Multicomponent Reactions

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