About: The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane

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About: The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane Goto Sponge NotDistinct Permalink

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scientific article published on November 1, 1992

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rdf:type	Item
description	article científic (ca) article scientific (oc) articol științific (ro) artigo científico (gl) artikulong pang-agham (tl) scienca artikolo (eo) teaduslik artikkel (et) tieteellinen artikkeli (fi) tudományos cikk (hu) vitenskapelig artikkel (nb) vitskapeleg artikkel (nn) επιστημονικό άρθρο (el) мақолаи илмӣ (tg) מאמר מדעי (he) სამეცნიერო სტატია (ka) บทความทางวิทยาศาสตร์ (th) artikel ilmiah (id) naučni članak (sr-el) мақолаи илмӣ (tg-cyrl) سائنسی مضمون (ur) مقالهٔ علمی (fa) artículu científicu espublizáu en 1992 (ast) maqolai ilmiy (tg-latn) 1992 nî ê lūn-bûn (nan) 1992年の学術論文 (ja) 1992年学术文章 (zh-cn) 1992年学术文章 (zh-sg) 1992年学术文章 (zh-hans) 1992年学术文章 (wuu) 1992年学术文章 (zh-my) 1992年學術文章 (zh) 1992年學術文章 (zh-hk) 1992年學術文章 (zh-tw) 1992年學術文章 (zh-hant) 1992年學術文章 (yue) 1992年學術文章 (zh-mo) 1992년 논문 (ko) ১৯৯২-এ প্রকাশিত বৈজ্ঞানিক নিবন্ধ (bn) 1992 թվականի նոյեմբերին հրատարակված գիտական հոդված (hy) 1992 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած (hyw) bài báo khoa học xuất bản ngày 1 tháng 11, 1992 (vi) научна статия, публикувана на 1 ноември 1992 г. (bg) vetenskaplig artikel publicerad den 1 november 1992 (sv) 1 Kasım 1992'de yayımlanmış bilimsel makale (tr) научни чланак објављен 1. новембар 1992. (sr) научни чланак објављен 1. новембар 1992. (sr-ec) videnskabelig artikel offentliggjort den 1. november 1992 (da) wetenschappelijk artikel gepubliceerd op 1 november 1992 (nl) article scientifique publié le 1 novembre 1992 (fr) articolo scientifico pubblicato il 1 novembre 1992 (it) artikull shkencor i botuar më 1 nëntor 1992 (sq) artykuł naukowy opublikowany 1 listopada 1992 (pl) scientific article published on 1 November 1992 (en-gb) scientific article published on November 1, 1992 (en) artículo científico publicado el 1 de noviembre de 1992 (es) vedecký článok publikovaný 1. novembra 1992 (sk) vědecký článek publikovaný 1. listopadu 1992 (cs) mokslinis straipsnis, publikuotas 1992 m. lapkričio 1 d. (lt) znanstveni članek objavljen 1. november 1992 (sl) artigo científico publicado em 1 de novembro de 1992 (pt) artigo científico publicado em 1 de novembro de 1992 (pt-br) im 1. November 1992 veröffentlichter wissenschaftlicher Artikel (de) научная статья опубликованная 1 ноября 1992 г. (ru) наукова стаття, опублікована 1 листопада 1992 (uk) مقالة علمية نشرت في نوفمبر 1992 (ar)
publication date	wds:Q35161112-4044A1A4-60E7-47D9-972B-D9CD33724DEB
publication date	1992-11-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q35161112-F34A99E0-5BB6-4447-9A47-7D16860E897A
language of work or name	English
cites work	wds:Q35161112-084F1350-8736-4A9A-9098-015C4F3D3436 wds:Q35161112-6676722C-4DB5-487D-A3BA-0587613A21F9 wds:Q35161112-68ECBF63-7C51-4F90-BA2D-5B8CA18CB816 wds:Q35161112-6DF06DFF-E251-4BD4-9F72-83A8323E96D2 wds:Q35161112-90F3B698-1725-4E6A-AF87-77810ECBC2BE wds:Q35161112-9E95D62E-F286-4BE4-A2C1-50B54504562F wds:Q35161112-A8B4B907-2EA8-418A-930F-CA6A6183CA9A wds:Q35161112-CC8E99AE-33BA-459B-944D-FDCFDBB51BCD wds:Q35161112-D8D72CD2-FDEA-4E34-8245-F8AFA07D8A7A wds:Q35161112-DD9BBE4D-20D3-45C2-8DE7-4AECB1D35F30
cites work	The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction. DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity Differences defined by bone marrow transplantation suggest that lpr and gld are mutations of genes encoding an interacting pair of molecules Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice Tolerance-related V beta clonal deletions in normal CD4-8-, TCR-alpha/beta + and abnormal lpr and gld cell populations
author name string	wds:Q35161112-9C464700-BDB2-404C-8960-DBA80752F278 wds:Q35161112-9E402353-5E02-4844-85A7-4A00E3B71D06
author name string	P. L. Cohen R. A. Eisenberg
rdfs:label	The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane (en) The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane (nl) The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane (ast)
skos:prefLabel	The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane (en) The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane (nl) The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane (ast)

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