About: Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

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About: Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity Goto Sponge NotDistinct Permalink

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scientific article (publication date: 1995)

Attributes	Values
rdf:type	Item
description	artículu científicu espublizáu en 1995 (ast) مقالة علمية (نشرت عام 1995) (ar) наукова стаття, опублікована в 1995 (uk) 1995 թուականին հրատարակուած գիտական յօդուած (hyw) 1995 թվականին հրատարակված գիտական հոդված (hy) wetenschappelijk artikel (gepubliceerd in 1995) (nl) article scientifique publié en 1995 (fr) scientific article (publication date: 1995) (en) im Januar 1995 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q29619700-467AFD15-5C9D-4017-A977-56D9818B17C0
publication date	1995-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q29619700-A63AE453-89FD-42F8-9061-11D589F38F7D
language of work or name	English
author name string	wds:Q29619700-45CEC933-BE46-4BBA-8179-FEB4364D0A5B
OpenCitations bibliographic resource ID	wds:Q29619700-30673D39-0B14-40C8-80D9-1B3E86F775D4
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/1166137
author name string	Trinchieri G
OpenCitations bibliographic resource ID	1166137
rdfs:label	Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity (en) Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity (ast)
skos:prefLabel	Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity (en) Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity (ast)
name	Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity (en) Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity (ast)
title	wds:Q29619700-79291A08-57D4-4E3F-AC1D-94432435C3FD
title	Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity (en)
page(s)	wds:Q29619700-023504A5-7795-49ED-B870-119AC50382F1
page(s)	251-76
instance of	wds:Q29619700-D50C4760-BD88-4304-8C69-D2C7107A4ACC wds:Q29619700-c548d30e-ea4d-4b52-8547-91becafe0eb6
instance of	review article scholarly article
main subject	wds:Q29619700-fa146484-fd51-4420-98fe-765d9beb4f4d
main subject	interleukins
PubMed ID	wds:Q29619700-76BF21AB-EDA9-4B64-929B-5F8BEFD901EE
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7612223
PubMed ID	7612223
published in	wds:Q29619700-78342174-C221-411C-9821-1DA14EAA55A8
published in	Annual Review of Immunology
volume	wds:Q29619700-0FE89F59-5D89-40E5-94FE-84506C504127
volume	13
DOI	wds:Q29619700-F1CD80FC-8693-4FA4-AC49-A4A2736F0185
DOI	http://dx.doi.org/10.1146/ANNUREV.IY.13.040195.001343
DOI	10.1146/ANNUREV.IY.13.040195.001343
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q29619700
is cites work of	Anti-inflammatory activity of myricetin from Diospyros lotus through suppression of NF-κB and STAT1 activation and Nrf2-mediated HO-1 induction in lipopolysaccharide-stimulated RAW264.7 macrophages The host response to Leishmania infection. Defective NK cell activity and Th1 response in IL-18-deficient mice Regulation of interferon-gamma production by IL-12 and IL-18. Hepatitis C virus genotype 1b core protein does not exert immunomodulatory effects on virus-induced cellular immunity IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells Transcript imaging of the development of human T helper cells using oligonucleotide arrays Involvement of receptor-interacting protein 2 in innate and adaptive immune responses Distinct requirements for the naturally occurring splice forms Stat4alpha and Stat4beta in IL-12 responses Multiple interleukin-18 injections promote both mouse Th1 and Th2 responses after sublethal Escherichia coli infection. The role of PI3K in immune cells CXC chemokine ligand (CXCL) 9 and CXCL10 are antagonistic costimulation molecules during the priming of alloreactive T cell effectors Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases Suppression of phagocytic and bactericidal functions of rat alveolar macrophages by the organic component of diesel exhaust particles Baculovirus-derived human immunodeficiency virus type 1 virus-like particles activate dendritic cells and induce ex vivo T-cell responses. Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node. Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12. Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphoma. Multiple sclerosis is associated with high levels of circulating dendritic cells secreting pro-inflammatory cytokines Tumor-associated macrophages: a molecular perspective Intracellular antimicrobial activity in the absence of interferon-gamma: effect of interleukin-12 in experimental visceral leishmaniasis in interferon-gamma gene-disrupted mice Differential expression of inducible nitric oxide synthase and IL-12 between peritoneal and splenic macrophages stimulated with LPS plus IFN-gamma is associated with the activation of extracellular signal-related kinase Cytokines in asthma Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease. [Production of Th1/Th2 cytokines and nitric oxide in Behçet's uveitis and idiopathic uveitis] Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion Dendritic cells. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity NO-aspirin protects from T cell–mediated liver injury by inhibiting caspase-dependent processing of Th1-like cytokines Antrum- and corpus mucosa-infiltrating CD4(+) lymphocytes in Helicobacter pylori gastritis display a Th1 phenotype. Immunomodulatory cytokines as therapeutic agents for melanoma Interleukin 12 and innate molecules for enhanced mucosal immunity Early IL-12 p70, but not p40, production by splenic macrophages correlates with host resistance to blood-stage Plasmodium chabaudi AS malaria. Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response Novel strategies for the prevention and treatment of Candida infections: the potential of immunotherapy Mechanisms of stimulation of the immune response by aluminum adjuvants Free IL-12p40 monomer is a polyfunctional adaptor for generating novel IL-12-like heterodimers extracellularly Early life T cell responses to pneumococcal conjugates increase with age and determine the polysaccharide-specific antibody response and protective efficacy. Partial impairment of cytokine responses in Tyk2-deficient mice Suppression of lymphoma and epithelial malignancies effected by interferon gamma Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription Cyclophilin C-associated protein: a normal secreted glycoprotein that down-modulates endotoxin and proinflammatory responses in vivo Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells Inherited interleukin 12 deficiency in a child with bacille Calmette-Guérin and Salmonella enteritidis disseminated infection Anti-inflammatory cytokines in asthma and allergy: interleukin-10, interleukin-12, interferon-gamma Intranasal immunization with recombinant Lactococcus lactis secreting murine interleukin-12 enhances antigen-specific Th1 cytokine production. VIP and PACAP inhibit IL-12 production in LPS-stimulated macrophages. Subsequent effect on IFNgamma synthesis by T cells High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10. In-situ tumor vaccination: Bringing the fight to the tumor Combined allogeneic tumor cell vaccination and systemic interleukin 12 prevents mammary carcinogenesis in HER-2/neu transgenic mice Effect of interleukin 12 on tumor induction by 3-methylcholanthrene

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